· António N, Elvas L, Goncalves L, Providencia LA. Cardiac resynchronization therapy in the elderly: A realistic option for an increasing population? International Journal of Cardiology 2012;155(1):49-51.

· Balça-Silva J, Neves SS, Gonçalves AC, Abrantes AM, Casalta-Lopes J, Botelho MF, Sarmento-Ribeiro AB, Silva HC. Effect of miR-34b Overexpression on the Radiosensitivity of Non-small Cell Lung Cancer Cell Lines. Anticancer Research . 2012, 32(5):1603-9.

· Bandello F, Cunha-Vaz JG, Chong NV, Lang GE, Massin P, Mitchell P, Porta M, Prunte C, Schlingemann R, Schmidt-Erfurth U. New approaches for the treatment of diabetic macular oedema: recommendations by an expert panel. Eye 2012; 26(4): 485-493.

· Baptista S, Bento AR, Goncalves J, Bernardino L, Summavielle T, Lobo A, Fontes Ribeiro C, Malva JO, Agasse F, Silva AP. Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures. Neuropharmacology 2012; 62 (7): 2413-2423.

· Bejarano E, Girao H, Yuste A, Patel B, Marques C, Spray DC, Pereira P, Cuervo AM. Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner. Molecular Biology of the Cell 2012; 23 (11): 2156-2169.

· Bernardino I, Mouga S, Almeida J, van Asselen M, Oliveira G, Castelo-Branco M. A Direct Comparison of Local-Global Integration in Autism and other Developmental Disorders: Implications for the Central Coherence Hypothesis. Plos One 2012; 7 (6) : Article Number: e39351 .

· Brito AF, Abrantes AM, Pinto-Costa C, Gomes AR, Mamede AC, Casalta-Lopes J, Gonçalves AC, Sarmento-Ribeiro AB, Tralhão JG, Botelho MF. Hepatocellular Carcinoma and Chemotherapy: The Role of p53. Chemotherapy. 2012 Dec 21;58(5):381-386.

· Carvalheiro T, Velada I, Valado A, Mendes F, Martinho A, Antonio N,Goncalves L, Providencia L, Pais ML, Paiva A. Phenotypic and functional alterations on inflammatory peripheral blood cells after acute myocardial infarction. Journal of Cardiovascular Translational Research 2012; 5 (3): 309-320. 

· Castilho AF, Aveleira CA, Leal EC, Simoes NF, Fernandes CR, Meirinhos RI, Baptista FI, Ambrosio AF. Heme Oxygenase-1 Protects Retinal Endothelial Cells against High Glucose- and Oxidative/Nitrosative Stress-Induced Toxicity. Plos One 2012; 7 (8):

· Castilho AF, Liberal JT, Baptista FI, Gaspar JM, Carvalho AL, Ambrosio AF. Elevated glucose concentration changes the contente and cellular localization of AMPA receptors on the retina but not in the hippocampus. Neuroscience 2012; 219: 23-32.

· Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A. Erythroid Disturbances Before and After Treatment of Portuguese Psoriasis Vulgaris Patients A Cross-Sectional and Longitudinal Study. American Journal of Clinical Dermatology 2012; 13 (1): 37-47.

· Coelho-Santos V, Goncalves J, Fontes-Ribeiro C, Silva AP. Prevention of methamphetamine-induced microglial cell death by TNF-alpha and IL-6 through activation of the JAK-STAT pathway. Journal of Neuroinflammation. 2012; 9: Article Number: 103.

· Cortez V, Santana M, Marques AP, Mota A, Rosmaninho-Salgado J, Cavadas C. Regulation of catecholamine release in human adrenal chromaffin cells by beta-adrenoceptors. Neurochemistry International 2012; 60 (4): 387-393. 

· Costa CB, Casalta-Lopes J, Andrade C, Moreira D, Oliveira A, Gonçalves AC, Alves V, Silva T, Dourado M, Nascimento-Costa JM, Sarmento-Ribeiro AB. Farnesyltransferase inhibitors: molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition. Anticancer Research. 2012; 32(3):831-8.

· Costa E, Coimbra J, Catarino C, Ribeiro S, Reis F, Nascimento H, Fernandes J, Miranda V, Faria MD, Belo L, Santos-Silva A. Major Determinants of BMP-2 Serum Levels in Hemodialysis Patients. Renal Failure 2012; 34 (10): 1355-1358.

· Costa GN, Vindeirinho J, Cavadas C, Ambrosio AF, Santos PF. Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose. Molecular and Cellular Neuroscience 2012; 50 (1): 113-123.

· Cotovio P, Neves M, Santos L, Macario F, Alves R, Mota A. Conversion to Everolimus in Kidney Transplant Recipients: To Believe or Not Believe? Transplantation Proceedings 2012; 44 (10): 2966-2970. 

· Curvo-Semedo L, Portilha MA, Ruivo C, Borrego M, Leite JS, Caseiro-Alves F. Usefulness of Perfusion CT to Assess Response to Neoadjuvant Combined Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer. Academic Radiology 2012; 19 (2): 203-213.

· Curvo-Semedo L, Lambregts DMJ, Maas M, Beets GL, Caseiro-Alves F, Beets-Tan RGH. Diffusion-weighted MRI in rectal cancer: Apparent diffusion coefficient as a potential noninvasive marker of tumor aggressiveness. Journal of Magnetic Resonance Imaging 2012; 35 (6): 1365-1371. 

· Direito B, Teixeira C, Ribeiro B, Castelo-Branco M, Sales F, Dourado A. Modeling epileptic brain states using EEG spectral analysis and topographic mapping. Journal of Neuroscience Methods 2012; 210 (2): 220-229.

· Donato P, Coelho P, Santos C, Bernardes A, Caseiro-Alves F. Correspondence between left ventricular 17 myocardial segments and coronary anatomy obtained by multi-detector computed tomography: an ex vivo contribution. Surgical and Radiologic Anatomy 2012; 34 (9): 805-810.

· Fernandes JC, Sereno J, Garrido P, Parada B, Cunha MFX, Reis F, Pintado ME, Santos-Silva A. Inhibition of Bladder Tumor Growth by Chitooligosaccharides in an Experimental Carcinogenesis Model. Marine Drugs 2012; 10 (2): 2661-2675.

· Ferreira A, Morgado AM, Silva JS. A Method for Corneal Nerves Automatic Segmentation and Morphometric Analysis, Computer Methods and Programs in Biomedicine 2012;107: 53–60. 

· Ferreira JF, Lobo J, Bessière P, Castelo-Branco M, Dias J. A Bayesian Framework for Active Artificial Perception . IEEE Trans Syst Man Cybern B Cybern. 2012 Sep 21. [Epub ahead of print]

· Ferreira MM, Botelho MF, Carvalho L, Silva MR, Oliveiros B, Carrilho EV. Evaluation of dentin formed in autogenous tooth transplantation in the dog: a comparison between one- and two-stage surgical techniques. Dental Traumatology 2012;28(2):97-100. 

· Ferreira S, Dormehl I, Botelho MF. Radiopharmaceuticals for bone metastasis therapy and beyond: a voyage from the past to the present and a look to the future. Cancer Biotherapy and Radiopharmaceuticals. 2012, 27(9):535-51. 

· Franqueira N, Cachulo ML, Pires I, Fonseca P, Marques I, Figueira J, Silva R. Long-Term Follow-Up of Myopic Choroidal Neovascularization Treated with Ranibizumab. Ophthalmologica 2012; 227 (1): 39-44.

· Goncalves A, Leal E, Paiva A, Teixeira Lemos E, Teixeira F, Ribeiro CF, Reis F, Ambrosio AF, Fernandes R. Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model. Diabetes Obesity & Metabolism 2012; 14 (5): 454-463.

· Goncalves J, Baptista F, Olesen MV, Fontes-Ribeiro C, Malva JO, Woldbye DP, Silva AP. Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment. Journal of Neurochemistry 2012; 123 (6): 1041-1053. 

· Graewe B, de Weerd P, Farivar R, Castelo Branco M. Stimulus dependency of object-evoked responses in human visual cortex: an inverse problem for category specificity. Plos One 2012; 7 (2): Article Number: e30727 .

· Lemos R, Figueiredo P, Santana I, Simoes MR, Castelo-Branco M. Temporal integration of 3D coherent motion cues defining visual objects of unknown orientation is impaired in amnestic mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer’s Disease 2012; 28 (4): 885-896.

· de Lemos ET, Oliveira J, Pinheiro JP, Reis F. Regular Physical Exercise as a Strategy to Improve Antioxidant and Anti-Inflammatory Status: Benefits in Type 2 Diabetes Mellitus. Oxidative Medicine and Cellular Longevity 2012; Article Number 741545.

· Mamede AC, Carvalho MJ, Abrantes AM, Laranjo M, Maia CJ, Botelho MF. Amniotic membrane: from structure and functions to clinical applications. Cell and Tissue Research. 2012 ;349 (2): 447-458. 

· Mamede AC, Pires AS, Abrantes AM, Tavares SD, Gonçalves AC, Casalta-Lopes JE, Sarmento-Ribeiro AB, Maia JM, Botelho MF . Cytotoxicity of Ascorbic Acid in a Human Colorectal Adenocarcinoma Cell Line (WiDr): In Vitro and In Vivo Studies. Nutrition and Cancer. 2012, 64(7):1049-57. 

· Martins-Branco D, Esteves AR, Santos D, Arduino DM, Swerdlow RH, Oliveira CR, Januario C, Cardoso SM. Ubiquitin proteasome system in Parkinson's disease: A keeper or a witness? Experimental Neurology 2012; 238 (2): 89-99.

· Matafome P, Santos-Silva D, Crisostomo J, Rodrigues T, Rodrigues L, Sena CM, Pereira P, Seica R. Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity. Archives of Physiology and Biochemistry 2012; 118 (2): 58-68.

· Moura C, Gano L, Mendes F, Raposinho PD, Abrantes AM, Botelho MF, Santos I, Paulo A. 99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation. European Journal of Medicinal Chemistry 2012; 50: 350-60.

· Parada B, Reis F, Pinto A, Sereno J, Xavier-Cunha M, Neto P. Rocha-Pereira P, Mota A, Figueiredo A, Teixeira F. Chemopreventive Efficacy of Atorvastatin against Nitrosamine-Induced Rat Bladder Cancer: Antioxidant, Anti-Proliferative and Anti-Inflammatory Properties. International Journal of Molecular Sciences 2012; 13 (7): 8482-8499.

· Pereira FC, Cunha Oliveira T, Viana SD, Travassos AS, Nunes S, Silva C, Prediger RD, Rego AC, Ali SF, Ribeiro CAF. Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice.

· Perrault I, Hanein S, Zanlonghi X, Serre V, Nocouleau M, Defoort-Delhemmes S, Delphin N, Fares-Taie L, Gerber S, Xerri O, EdelsonC, Goldenberg A, Duncombe A, Le Meur G, Hamel C, Silva E, Nitschke P, Calvas P, Munnich A, Roche O, Dollfus H, Kaplan J, Rozet JM. Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy. Nature Genetics 2012; 44 (9): 975-977.

· Perrault I, Saunier S, Hanein S, Filhol E, Bizet AA, Collins F, Salih MAM, Gerber S, Delphin N, Bigot K, Orssaud C, Silva E, et al. Mainzer-Saldino Syndrome Is a Ciliopathy Caused by IFT140 Mutations. American Journal of Human Genetics 2012; 90 (5): 864-870.

· Pires AL, Pinho M, Sena CM, Seica R, Leite-Moreira AF. Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide. American Journal of Physiology – Heart and Circulatory Physiology 2012; 302 (5): H1131-H1137

· Pires G, Nunes U, Castelo-Branco M. Comparison of a row-column speller vs. a novel lateral single-character speller: Assessment of BCI for severe motor disabled patients. Clinical Neurophysiology 2012; 123 (6): 1168-1181.

· Portugal CC, da Encarnacao, TG, Socodato R, Moreira SR, Brudzewsky D, Ambrosio AF, Paes-de-Carvalho R. Nitric Oxide Modulates Sodium Vitamin C Transporter 2 (SVCT-2) Protein Expression via Protein Kinase G (PKG) and Nuclear Factor-kappa B (NF-kappa B). Journal of Biological Chemistry 2012; 287 (6): 3860-3872.

· Prasov L, Masud T, Khalig S, Mehdi SQ, Abid A, Oliver ER, Silva ED, Lewanda A, Brodsky MC, Borchert M, Kelberman D, Sowden JC, Dattani MT, Glaser T. ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous. Human Molecular Genetics 2012; 21 (16): 3681-3694

· Priolli DG, Abrantes AM, Neves S, Batista JN, Cardinalli IA, Botelho MF. A novel model of distal colon cancer in athymic mice. Acta Cir Bras. 2012, 27(6):355-60.

· Ribeiro MJ, Violante MI, Bernardino I, Ramos F, Saraiva J, Reviriego P, Upadhyaya M, Silva ED, Castelo-Branco M. Abnormal Achromatic and Chromatic Contrast Sensitivity in Neurofibromatosis Type 1. Investigative Ophthalmologyl and Visual Sciences 2012; 53 (1): 287-293.

· Ribeiro S, Faria MD, Mascarenhas-Melo F, Freitas I, Mendonca MI, Nascimento H, Rocha-Pereira P, Miranda V, Mendonca D, Quintanilha A, Belo L, Costa E, Reis F, Santos-Silva A. Main Determinants of PON1 Activity in Hemodialysis Patients. American Journal of Nephrology 2012; 36 (4): 317-323.

· Santana MM, Chung KF, Vukicevic V, Rosmaninh-Salgado J, Kanczkowski W, Cortez V, Hackmann K, Bastos CA, Mota A, Schrock E, Bornstein SR, Cavadas C, Ehrhart-Bornstein M. Isolation, Characterization, and Differentiation of Progenitor Cells from Human Adult Adrenal Medulla. Stem Cells Translational Medicine 2012; 1 (11): 783-791.

· Santiago I, Loureiro R, Curvo-Semedo L, Marques C, Tardaguila F, Matos C, Caseiro-Alves F. Congenital Cystic Lesions of the Biliary Tree. American Journal of Roentgenology 2012; 198 (4): 825-835. 

· Schitine C, Xapelli S, Agasse F, Sarda-Arroyo L, Silva AP, De Melo Reis RAD, de Mello FG, Malva JO. Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures. European Journal of Neuroscience. 2012; 35(11): 1672-1683.

· Sena CM, Matafome P, Crisostomo J, Rodrigues L, Fernandes R, Pereira P, Seica RM. Methylglyoxal promotes oxidative stress and endothelial dysfunction. Pharmacological Research 2012; 65 (5): 497-506. 

· Serra AC, Rocha Gonsalves AM, Laranjo M, Abrantes AM, Gonçalves AC, Sarmento-Ribeiro AB, Botelho MF. Synthesis of new 2-galactosylthiazolidine-4-carboxylic acid amides. Antitumor evaluation against melanoma and breast cancer cells. European Journal of Medicinal Chemistry.2012; 53:398-402. 

· Silva R. Myopic Maculopathy: A Review. Ophthalmologica 2012; 228 (4): 197-213.

· Silva S, Ribeiro CAF. Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in Human Cerebral Blood Vessels: Pharmacological Demonstration of the 5-HT1B Receptor Functionality Loss. Pharmacology 2012; 89 (1-2): 29-36.

· Socodato R, Santiago FN, Portugal CC, Domingues AF, Santiago AR, Relvas JB, Ambrosio AF, Paes-de-Carvalho R. Calcium-permeable alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion. Journal of Biological Chemistry 2012; 287 (46): 38680-38694.

· Tralhão JG, Abrantes AM, Hoti E, Cardoso D, Figueirinha R, Botelho MF, Castro-Sousa F. Hepatic extraction fraction: interest of its quantification in patients with hepatic tumours. Hepatogastroenterology. 2012, 59(117):1507-11.

· Tralhao JG, Hoti E, Oliveiros B, Botelho MF, Sousa FC. Study of Perioperative Liver Function by Dynamic Monitoring of ICG-Clearance. Hepatogastroenterology. 2012, 59(116):1179-83.

· van Asselen M, Almeida I, Julio F, Januario C, Campos EB, Simoes M, Castelo-Branco M. Implicit Contextual Learning in Prodromal and Early Stage Huntington's Disease Patients. Journal of the International Neuropsychological Society 2012; 18 (4): 689-696.

· Violante I, Ribeiro MJ, Cunha G, Bernardino I, Duarte JV, Ramos F, Saraiva J, Silva E, Castelo-Branco M. Abnormal Brain Activation in Neurofibromatosis Type 1: A Link between Visual Processing and the Default Mode Network. Plos One 2012; 7 (6): Article Number: e38785.