Joana Gonçalves

Joana Gonçalves

In 2005, I got my B. Sc. degree in Biology in Faculty of Sciences and Technology of University of Coimbra. From 2005 to 2007, I was in Institute of Molecular Pathology and Immunology at the University of Porto (IPATIMUP) with a Fellowship of Initiation to Scientific Research.

In 2008, I started my PhD in Bioscience (Faculty of Sciences and Technology, University of Coimbra). This project aimed to disclose the role of pro-inflammatory cytokines and neuropeptide Y in methamphetamine-induced hippocampal dysfunction (SFRH/BD/35893/2007) and was held in Laboratory of Pharmacology and Experimental Therapeutic (Group D) under supervision of Doctor Ana Paula Silva. During my PhD, I developed same work in Laboratory of Neuropsychiatry, Rigshospitalet University Hospital, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark. More recently, I was granted with FEBS Short-Term Fellowship from Federation of the Societies of Biochemistry and Molecular Biology to spent 2 months in Laboratory of Psychobiology of Drug Addiction, Department of Psychobiology, Faculty of Psychology of UNED, Madrid, Spain.

Since June 2012, I have a Pos-Doc Fellow in a project entitled “Centro-07-ST24-FEDER-002005 - From molecules to man: novel diagnostic imaging tools in neurological and psychiatric disorders”, under supervision of Professor Miguel Castelo-Branco (Group B).

Scientific Interest:

Neuroscience; Neuropharmacology; Neuropathology; Neuroimaging; Neurofibromatosis type 1; Drug of abuse

5 Keys Publications:

  • Gonçalves J, Baptista S, Olesen MV, Ribeiro CF, Malva JO, Woldbye DP and Silva AP (2012) Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment. J Neurochem, 123(6):1041-53.
  • Gonçalves J, Ribeiro CF, Malva JO and Silva AP (2012) Protective role of neuropeptide Y Y2 receptors in cell death and microglial response following methamphetamine injury. Eur J Neurosci, 36(9):3173-3183.
  • Coelho-Santos V*, Gonçalves J*, Ribeiro CF and Silva AP (2012) Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK/STAT pathway. J Neuroinflammation, 9(1):103. (* These authors contributed equally to this work)
  • Gonçalves J, Baptista S, Martins T, Milhazes N, Borges F, Fontes Ribeiro CA, Malva JO and Silva AP (2010) Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin. Eur. J. Neurosci., 31(2):315-26.
  • Gonçalves J, Martins T, Ferreira R, Milhazes N, Borges F, Fontes Ribeiro CA, Malva JO, Macedo TR and Silva AP (2008) Methamphetamine-induced early increase of IL-6 and TNF-α mRNA expression in the mice brain. Ann. N.Y. Acad. Sci. 1139, 103-111.
Phone Number:+ 351 239 488510
ICNAS Building
Email: jgoncalves@fmed.uc.pt

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