Ana Cristina Aguiar dos Santos
Academic Record:
Graduation as Technologist of Diagnosis and Therapeutics in Pathology, Cytology and Tanatology, Coimbra Health Technology College June, 1985.
Graduation in Biology, Science Faculty, University of Coimbra (FCTUC), September, 1988.
Master degree in Cellular Biology, FCTUC, May, 1993.
PhD in Medical Sciences, Medical School, University of Coimbra (FMUC), October, 2002.
Present Professional and Scientific Activities:
Auxiliary Researcher, Medical School, University of Coimbra, from October 2002 to current date; Professor of Introduction to Nuclear Chemistry and Radiopharmacy of the Integrated Masters in Biomedical Engeneering of the FCTUC/FMUC, since 2005/06.
Other positions: Professor of Biophysics and Biochemistry of the Nurse’s College of Coimbra since 1989, Supervisor of Master and Degree students from the FCTUC and Piaget Institute since 2005/06.
Scientific Interest:
Biophysics, Liposome production with potential clinical application, Biodistribution and pharmacokinetics studies of radiopharmaceuticals in experimental animal models, Macrphage and fibroblast criopreservation bank, Citotoxicity and adhesion testing of biomaterials, Labelling of new compounds for nuclear medicine imaging and therapy. Cellular Biology, Radiopharmacy and Pharmacology, Radiochemistry, Tumour models, in vitro binding assays.
5 Keys Publications:
- F.
Caseiro Alves, Paulo Donato, A. Dean Sherry, Atif Zaheer, Shanrong Zhang,
Angelo Josue M. Lubag, Matthew E. Merrit, Robert E. Lenkinski, John V.
Frangioni, Maria Neves, M. Isabel Machado Prata, A.C. Santos, João J. P. de
Lima, Carlos F.G.C. Geraldes (2003). Silencing of Phosphonate-Gadolinium
Magnetic Resonance Imaging Contrast by Hydroxyapatite Binding.Investigative Radiology
38, 12.
- Lanthanide (III) Complexes of DOTA-Glycoconjugates: a potential new class of
lectin-mediated medical imaging agents. JP André, CFGC Geraldes, JA
Martins, AE Merbach, MIM Prata, AC Santos, JJP Lima, E Toth. Chem Eur J, 10,
5804-5816, 2004.
-M. C. Oliveira, M. Videira, A. Almeida, L. Gano, M. Watanabe, T. Thiemann,
A.C. Santos, F. Botelho, C. Oliveira "Synthesis and biodistribution
studies of two novel radioiodinated areno-annelated
estra-1,3,5(10),16-tetraene-3-ols as promising estrogen receptor
radioligands", Journal of Labelled Compounds and Radiopharmaceuticals,
2006, 49,559-569.
- Oliveira MC, Videira M, Almeida A, Gano L, Watanabe M, Thiemann T, Santos AC,
Botelgo MF, Oliveira C. Auger emitters in radiotherapy: novel estrogen receptor
radioligands, The Quarterly Journal of Nuclear Medicine and Molecular Imaging,
2006, 50, 48-49.
- J.B. Livramento, C. Weidensteiner, M.I.M. Prata, P.R. Allegrini, C.F.G.C.
Geraldes, L. Helm, R. Kneuer, A.E. Merbach, A.C. Santos, P. Schmidt, É. Tóth,
First in vivo MRI assessment of a self-assembled metallostar compound endowed
with a remarkable high field relaxivity, Contrast Media Mol. Imaging, 1, 30-39
(2006)
Phone Number:+351 239 480 240
Email: cristina@ibili.uc.pt