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UC.PT

Coimbra Laser Lab

LaserLab Training School 2017

Training School on Laser Applications for Biology and Biomolecular Systems: an authentic hands-on experience

3-7 July 2017, Coimbra, Portugal

The Training School on Laser Applications for Biology and Biomolecular Systems is focused on the application of laser-based techniques to biologically relevant molecules and systems. A selected number of significant lectures on the School field of application will be given by renowned invited scientists. Spectroscopic, time-resolved and microscopy techniques will be presented and available for selected hands-on experiments by the targeted users from the Biology, Medicinal Chemistry, Pharmacy and Medical community. Students with background in Physics or Chemistry with the objective of studying biomolecular systems are also welcomed.

Training course description to download

Objectives

Contribute for an integrating view of experimental laser-based methods applied to Biomolecular sciences;

Improve the awareness on safety and responsible use of laser sources in Biomolecular sciences;

Present cutting-edge laser-based techniques and applications:

Train young researchers on laser based tools with application in relevant Biology and Biomolecular systems.

Sponsors

Laserlab Europe, Newport, Spectra-Physics, MTBrandão, VisualSonics, iThera-Medical, Sarspec, ADLaser, Luzitin and LaserLeap

Venue

Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal

University of Coimbra, founded in 1290, was recently recognized as a world heritage by UNESCO. Over the centuries Roman, Visigoths, Moors and Christians lived in the city of Coimbra. The present-day character of the city is the legacy of the great epochs of the European and Moors culture. Coimbra’s architecture combines Roman (aqueduct and cryptoporticus), Gothic (Santa Clara-a-Velha Monastery), Renaissance (Santa Cruz Monastery) and Baroque (Joanina Library) styles. Walking around the Old Town you can feel surrounded by history from tempestuous time. For many centuries the former Portuguese capital has had thriving intellectual and cultural life – for that it remains to be called Lusitanian Athens. The city would be never the same without its students proudly wearing their traditional clothes, and keeping cultural tradition alive through the ages. Coimbra pampers inhabitants and visitors with living tradition, great weather and delicious vine and food.

Travel information to download

Duration

One week: 3-7 July 2017; Lectures and demonstrations: 2 days; Hands-on training: 3 days

Target audience

The Training School on Laser Applications for Biology and Biomolecular Systems is designed to enthral and educate new laser users from the Biology, Pharmacy and Medical scientific communities with limited knowledge and experience in laser-based research, but with high potential for effective use of laser-based science and technology and laser facilities, namely in the Biomedical diagnosis and treatment field. The study of relevant Biomolecules and Biocompatible molecules by spectroscopic, time-resolved and microscopy techniques covered in the School is aimed to enhance the knowledge and understanding young graduate, PhD and post-doctoral students of Biology, Biochemistry, Medicinal Chemistry, Pharmacy and related Medical fields. We wish to demonstrate that the knowledge of laser-based techniques and methods can help in their specific studies and fields of knowledge. Chemistry and Physical sciences young researchers are also welcomed.

Lecturers

Peter Hamm (Zurich, CH)

Tony Parker (CTFC-CLF, UK)

Goreti Sales (ISEP/IPP, Portugal)

Luis G. Arnaut (CLL, Portugal)

Margarida C. Pires (UL, Portugal)

Steven Ford (Munich, Germany)

Programme

Scientific topics

Laser safety

Time-resolved spectroscopy and imaging to study structure-function relationships in biological systems

Biocompatible molecules for treatment and diagnostic

Spectroscopic analysis of biological samples

Ultrafast IR transient absorption of relevant biological molecules

Light interaction with biological tissues

In-vivo Photoacoustic imaging

Training topics

Biomolecules and biocompatible compounds spectroscopic characterization

Steady-state spectroscopy: Absorption, fluorescence, IR and Raman spectroscopy.

Time-resolved spectroscopy: Transient absorption (fs up to ms), Single photon counting, Singlet oxygen phosphorescence, Photoacoustic calorimetry.

Data Analysis: Convolution, Fitting functions, Statistics, Data treatment

Imaging/Diagnostic: Photoacoustic tomography, Multiphoton microscopy, Raman mapping, Spatially Offset Raman Spectroscopy

Therapy: Photodynamic therapy

Lab work and School format

Technical aspects, instrumentation and hands-on experiments on time resolved transient absorption spectroscopy, single photon counting, singlet oxygen phosphorescence, photoacoustic calorimetry and IR spectroscopy will be done. Imaging techniques of multiphoton microscopy and Raman mapping will be reviewed. Demonstration sessions include the use of laser characterization instruments, Spatially Offset Raman Spectroscopy and sensors for selective recognition of biomolecules. In the interactive “Results analysis” sessions we will explore data analysis using state-of-the-art methodologies and deconvolution methods and use non-proprietary software.

Preliminary Timetable to download

Scholarships application and registration

The school is free of charge for the selected attendees (scholarships cover the cost of the school, accommodation in shared rooms and several meals). Lab work may be limited to about 20 attendees. Scholarships recipients may have to arrange and pay for their own travel costs to the event, although a number of travel grants will be available for early registrations. The deadline for receiving scholarship application forms is 1 March 2017 and all applicants will be informed of the decision on awarding them a scholarship by 15 March 2017. The decision of the project organizing committee panel will be final. The deadline for confirmation is 24 March 2017. Applications for attendance and scholarship should include the progress status of PhD or post-doc project (in years) and present and near future research topics (fill and send the Application Form to download).

Training School organizing committee

Carlos Serpa, serpasoa@ci.uc.pt

Igor Reva

Fábio Schaberle

João Pina

Documents to download