Phenotypes to Genotypes of Ageing and Degenerative Disease

Coordinator: Paulo Pereira


The RP2 programme aims at an integrated multidisciplinary approach covering various aspects from early genetic mechanisms of age-related diseases and intermediate mechanisms of age-related cell damage, ending up in development of improved means to characterize and validate complex phenotypes such as of age-related retinal degeneration. This programme includes 3 sub-programmes:

Phenotyping, identification of risk markers and testing emerging therapies

(Coordinator: José Cunha-Vaz)

Genotypes to phenotypes: molecular mechanism of degeneration and design of new therapies

(Coordinator: Paulo Pereira)

Functional Studies of Drug Action at Systems Level

(Coordinator: Frederico Teixeira)

Understanding and treating diabetes and diabetic endothelial dysfunction

(Coordinator: Raquel Seiça)