Chemical Process Engineering and Forest Products Research Centre

António Guiomar

António Guiomar

António Jorge R. F. Guiomar

Auxiliary Researcher at the Department of Life Sciences, University of Coimbra

PhD, University of Leeds (UK), 1997

MSc by Research, University of Leeds (UK), 1989

BSc in Biochemistry, University of Coimbra, 1987

E-mail address
Teaching activities

Course unit "Biomaterials", belonging to the MSc in Biochemistry and to the MSc in Cellular and Molecular Biology

Couse unit "Biochemistry Laboratory Introduction", belonging to the BSc in Biochemsitry

Research group
Computing, Statistics & Materials (CEM)
Research interests

Controlled drug release

Hemocompatibility of materials

Self-assembled monolayers (SAMs) of alkanethiols on gold

Attachment of biomolecules to surfaces

Surface modification and characterization

Funded research projects

StereoStrat - Sterilization of clinically active hydrogels: looking for efficient strategies, PTDC/CTMBIO/
3640/2014 (F.C.T.); Partner

SurfLenses - Surface modifications to control drug release from therapeutic ophthalmic lenses, M-Era.net Transnational Call 2012 - 2014-2016; Partner

NanoBioCats – Novel nanostructured polymeric materials for concurrent biocatalysis and separation, PTDC/CTM-POL/112289/2009 (F.C.T.) - 2011-2014; Partner

Nanochemistry of magnetic/luminescent composites for in vitro medical diagnosis applications, PTDC/QUI/67712/2006 (F.C.T.) - 2008-2010; Partner

Development of new polyurea/polyurethane-based membranes for blood oxygenators - POCTI/FCB/47661/2002 (F.C.T.) - 2002-2006; Partner

Key publications

A. F. R. Pimenta, A. P. Vieira, R. Colaço, B. Saramago, M. H. Gil, P. Coimbra, P. Alves, D. Bozukova, T. R. Correia, I. J. Correia, A. J. Guiomar, A. P. Serro, “Controlled release of moxifloxacin from intraocular lenses modified by Ar plasma-assisted grafting with AMPS or SBMA: an in vitro study”, Colloids Surf. B, Biointerfaces, 156, 95-103 (2017)

H. P. Filipe, D. Bozukova, A. Pimenta, A. P. Vieira, P. Alves, P. Coimbra, A. J. Guiomar, M. H. Gil, J. L. G. Mata, A. P. Serro, “Surface modification of intraocular lenses towards controlled drug delivery”, Acta Ophthalmol., 93, S255, ABS15-0561 [Abstracts from the 2015 European Association for Vision and Eye Research Conference] (2015)

T. R. Silva, D. P. Rodrigues, J. M. S. Rocha, M. H. Gil, S. C. S. Pinto, J. A. Lopes-da-Silva and A. J. Guiomar, “Immobilization of trypsin onto poly(ethylene terephthalate)/poly(lactic acid) nonwoven nanofiber mats”, Biochem. Eng. J., 104, 48-56 (2015)

P. C. Pinheiro, C. T. Sousa, J. P. Araújo, A. J. Guiomar e T. Trindade, “Functionalization of nickel nanowires with a fluorophore aiming at new probes for multimodal bioanalysis”, J. Colloid Interface Sci., 410, 21−26 (2013)

M. C. Besteiro, A. J. Guiomar, C. A. Gonçalves, V. A. Bairos, M. N. de Pinho e M. H. Gil, “Characterization and in vitro hemocompatibility of bi-soft segment, polycaprolactone-based poly(ester urethane urea) membranes”, J. Biomed. Mater. Res. 93A, 954-964 (2010)

A. L. Daniel-da-Silva, S. Fateixa, A. J. Guiomar, B. F. O. Costa, N. J. O. Silva, T. Trindade, B. J. Goodfellow e A. M. Gil, "Biofunctionalized magnetic hydrogel nanospheres of magnetite and k-carrageenan", Nanotechnology, 20, 355602 (2009)

M. A. Martins, M. C. Neves, A. C. C. Esteves, P. I. Girginova, A. J. Guiomar, V. S. Amaral e T. Trindade, “Biofunctionalized ferromagnetic CoPt3/polymer nanocomposites”, Nanotechnology, 18, 215609 (2007)

D. P. Queiroz, I. M. Pinto, M. C. F. Besteiro, A. F. M. Silva, M. H. Gil, A. J. Guiomar e M. N. de Pinho, "Surface and Hemocompatibility Studies of Bi-Soft Segment Polyurethane Membranes", Int. J. Artif. Organs, 29, 866-872 (2006)

A. J. Guiomar, J. T. Guthrie e S. D. Evans, “Use of Mixed Self-Assembled Monolayers in a Study of the Effect of the Micro-Environment on Immobilized Glucose Oxidase”, Langmuir, 15, 1198–1207 (1999)

A. Alcantara, M. H. Gil, A. J. Guiomar, M. Belmonte, M. C. Sobral, C. Torres e J. V. Sinisterra, “Organic Reactions Catalysed by Insolubilised Enzymes. Part III. Synthesis of Peptides Catalyzed by alpha-Chymotrypsin Immobilised on Graft Copolymers”, J. Mol. Catal., 101, 255–265 (1995)

Theses supervision

Helga Marina Paiva, Implementation of na antibiotic controlled release system in commercial soft contact lenses, MSc thesis (Biochemistry), Universidade de Coimbra (2017; unfinished). Supervisor.

Carlos André Videira Ramos (2013), Study of the effect of surface hydrophilicity in blood plasma coagulation, employing self-assembled monolayers of alkanethiols on gold, BSc Thesis, Universidade de Coimbra, 2013

Teresa Raquel Ferreira da Silva, Covalent immobilization of trypsin onto polymeric nanofibers prepared by electrospinning, MSc thesis (Chemical Engineering), Universidade de Coimbra (2014). Co-supervision with Jorge M. S. Rocha (UC)

Mónica Cristina Faria Besteiro (2012). Development of hemocompatible polyurethane-polyurea membranes for use in blood oxygenators, PhD Thesis, Instituto Superior Técnico. Co-supervision with M. Norberta de Pinho (IST)

Mónica Cristina Faria Besteiro (2007). Preparation and characterization of polyurethane-polyurea membranes for extracorporeal blood oxigenation devices, MSc Thesis, Universidade de Coimbra, 2007; Co-supervision with M. Helena Gil (FCTUC)

Other information

ORCID ID: 0000-0002-1372-5954

Projecto de divulgação de ciência: “My first contact with Science”, PcC170 (Call “Pais com a Ciência”, Ciência Viva, 2012) - 2013; coordinator of activities in the Materials area

For a full list of publications please see http://apps.uc.pt/mypage/staff/aguiomar/en