Cândida G. Silva
Cândida G. Silva currently
holds a post-doctoral fellowship in the project "Ibercivis.pt – A volunteer computing platform for the Iberian
Peninsula", financed by UMIC - Agência para
a Sociedade do Conhecimento IP.
After completing a degree in
Mathematics and Computer Sciences at the University of Minho (2003), she pursued
post-graduated studies at the University of Lisbon in the area of
Bioinformatics (2004). She received her Ph.D. degree in 2010, in the area of
Chemistry, specialty Biology Chemistry, from the University of Coimbra. The
work leading to her doctoral thesis involved management and mining of data
originated from molecular dynamics protein unfolding simulations, bridging two
scientific domains: computational biology and information technology.
Her
research interests focus on machine learning, data mining, drug discovery, citizen science, e-
science, volunteer computing and data warehousing.
Selected Publications
- Silva, C.G., Simões, C.J.V., Carreiras, P., Brito, R.M.M. (2016) "Enhancing Scoring Performance of Docking-Based Virtual Screening Through Machine Learning". Current Bioinformatics 11 (4), pp. 408-420.
- Rodrigues, J.R.,
Simões, C.J.V., Silva, C.G., Brito, R.M.M. (2010) "Potentially amyloidogenic
conformational intermediates populate the unfolding landscape of transthyretin:
insights from molecular dynamics simulations", Protein Sci. 19(2),
202-219.
- Swain, M., Silva,
C.G., Loureiro-Ferreira, N., Ostropytskyy, V., Brito, J., Riche, O., Stahl, F.,
Dubitzky, W., and Brito, R.M.M. (2010). "P-found: Grid-enabling distributed
repositories of protein folding and unfolding simulations for data mining". Futur. Gener.
Comp. Syst. 26(3), 424-433.
- Ferreira, P.G., Silva, C.G., Azevedo, P.J., Brito, R.M.M (2008) "Spatial
Clustering of Molecular Dynamics Trajectories in Protein Unfolding
Simulations", Lecture Notes in Bioinformatics, vol. 5488, pp. 156-166, Springer-Verlag.
- Ferreira, P.G., Silva, C.G., Brito, R.M.M., Azevedo, P.J. (2007) "A
Closer Look on Protein Unfolding Simulations through Hierarchical
Clustering", Proceedings of the 2007 IEEE Symposium on Computational
Intelligence in Bioinformatics and Computational Biology,
CIBCB’07, Honolulu, Hawai, pp. 461-468.
- Silva, C.G., Ostropytskyy, V., Loureiro-Ferreira, N., Berrar, D.,
Dubitzky, W., Brito, R.M.M. (2006) "P-found: The Protein Folding and
Unfolding Simulation Repository", Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB’06, Toronto, Canadá, pp. 101-108.
