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Faculdade de Medicina

Publicações Científicas


2 Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.
Lips ES, Cornelisse LN, Toonen RF, Min JL, Hultman CM, the International Schizophrenia Consortium (para a FMUC – António Macedo), Holmans PA, O’Donovan MC, Purcell SM, Smit AB, Verhage M, Sullivan PF, Visscher PM, Posthuma D.
Molecular Psychiatry; 17: 996–1006, 2012.
99m Tc in the evaluation of microleakage of composite resin restorations with SonicFill™ . An in vitro experimental model.
Carrilho E, Abrantes M, Casalta-Lopes J, Botelho F, Paula A, Ambrósio P, Marco CM, Rebelo D, Marques J, Polido M, Ferreira MM
Open Journal of Stomatology 2012; 2: 340-347
99m Tc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation.
Moura C, Gano L, Mendes F, Raposinho PD, Abrantes AM, Botelho MF, Santos I, Paulo A.
Eur J Med Chem. 2012 Apr;50:350-60. doi: 10.1016/j.ejmech.2012.02.014. Epub 2012 Feb 14
β(1,3)-glucan synthase complex from Alternaria infectoria, a rare dematiaceous human pathogen.
Anjos J, Fernandes C, Silva BM, Quintas C, Abrunheiro A, Gow NA, Gonçalves T.
Med Mycol. 2012 Oct;50(7):716-25. 


A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia
  Middleton F, Carvalho C, Morley C, Fanous A, Conti D, Knowles JA, Ferreira CP, Macedo A, Azevedo MH, Pato CN, Stone JL, Ruderfer DM, Ferreira MA, Purcell SM, Stone JL, Chambert K, Ruderfer DM, Kuruvilla F, Gabriel SB, Ardlie K,et al.

Daly MJ, Scolnick EM, Sklar P. J Med Genet. 2012 Feb;49(2):96-103.

Abnormal achromatic and chromatic contrast sensitivity in neurofibromatosis type 1.
Ribeiro MJ, Violante IR, Bernardino I, Ramos F, Saraiva J, Reviriego P, Upadhyaya M, Silva ED, Castelo-Branco M.

Invest Ophthalmol Vis Sci. 2012 Jan 25;53:287-93.

Abnormal Brain Activation in Neurofibromatosis Type 1: A Link between Visual Processing and the Default Mode Network. Violante IR, Ribeiro MJ, Cunha G, Bernardino I, Duarte JV, Ramos F, Saraiva J, Silva E, Castelo-Branco M.PLoS One. 2012;7:e38785. Epub 2012 Jun 18.
Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naïve T cells in dendritic cell clustering.
Chen Y, Adams E, Regateiro FS, Vaux DJ, Betz AG, Andersen KG, Waldmann H, Howie D.
Eur J Immunol. 2012 Jun;42(6):1436-48. doi: 10.1002/eji.201142207.
Acute myocardial Infarction: Historical notes.
Teixeira R, Gonçalves L, Gersh B.
Int J Cardiol. 2013 Jan 19. doi:pii: S0167-5273(12)01695-6.
Adenosine A(2A) receptors modulate glutamate uptake in cultured astrocytes and gliosomes.
Matos M, Augusto E, Santos-Rodrigues AD, Schwarzschild MA, Chen JF, Cunha RA, Agostinho P.
Glia. 2012 May;60(5):702-16. doi: 10.1002/glia.22290. Epub 2012 Feb 1. PubMed PMID: 22298379.
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs.
Bousquet J, Schünemann HJ, Samolinski B, Demoly P, Todo-Bom A, World Health Organization Collaborating Center for Asthma and Rhinitis.
J Allergy Clin Immunol. 2012 Nov;130(5):1049-62.
Alzheimer’s disease and diabetes: an integrative view of the role of mitochondria, oxidative stress, and insulin.
Moreira PI.J
Alzheimers Dis. 2012;30:S199-S215.
Alzheimer disease as a vascular disorder: Where do mitochondria fit?
Correia SC, Santos RX, Cardoso S, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI.
Exp Gerontol. 2013;47:878-86.
Amniotic membrane: from structure and functions to clinical applications.
Mamede AC, Carvalho MJ, Abrantes AM, Laranjo M, Maia CJ, Botelho MF.
Cell Tissue Res. 2012 Aug;349(2):447-58. doi: 10.1007/s00441-012-1424-6. Epub 2012 May 18. Review.
PMID: 22592624 [PubMed - indexed for MEDLINE]
Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.
Mota SI, Ferreira IL, Pereira C, Oliveira CR, Rego AC.
Curr Alzheimer Res. 2012 May 21. [Epub ahead of print]
Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.
Ferreira IL, Bajouco LM, Mota SI, Auberson YP, Oliveira CR, Rego AC.Cell Calcium. 2012 Feb;51(2):95-106.PMID: 22177709.
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.
Costa R.O., Ferreiro E., Martins I., Santana I., Cardoso S.M., Oliveira C.R., Pereira C.M.
(2012) Neurobiol Aging 33:824.e5-824.e16.
An interdisciplinary debate initiated by the European Society of Cardiology Working Group on Valvular.
Naber CK, Prendergast B, Thomas M, Vahanian A, Iung B, Rosenhek R, Tornos P, Otto CM, Antunes MJ, Kappetein P, Lange R, Wendler O.
EuroIntervention. 2012;7:1257-74.
Analysis of Cell Cycle and Replication of Mouse Macrophages after In Vivo and In Vitro Cryptococcus neoformans Infection Using Laser Scanning Cytometry
Carolina Coelho, Lydia Tesfa, Jinghang Zhang, Johanna Rivera, Teresa Gonçalves and Arturo Casadevall.
Infect. Immun. 2012, 80(4):1467. DOI: 10.1128/IAI.06332-11. Published Ahead of Print 17 January 2012.
Androgen responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile.
Vaz CV, Alves MG, Marques R, Moreira PI, Oliveira PF, Maia CJ, Socorro S.
Int J Biochem Cell Biol. 2012;44:2077-84.
Apoptosis deregulation influences chemoresistance to azaguanine in human leukemic cell lines. Sarmento-Ribeiro AB, Dourado M, Paiva A, Freitas A, Silva T, Regateiro F, Oliveira CR.
Cancer Invest 2012, Jun; 30(5): 331-342.
A novel model of distal colon cancer in athymic mice.
Priolli DG, Abrantes AM, Neves S, Batista JN, Cardinalli IA, Botelho MF.
Acta Cir Bras. 2012 Jun;27(6):355-60.
PMID: 22666751 [PubMed - in process]
Aortic stenosis in octogenarians and other high-risk groups: what can surgical valve replacement offer?
Antunes MJ.
Eur J Cardiothorac Surg. 2012;42:940-1.
Aortic valve surgery in patients who had undergone surgical myocardial revascularization.
Paupério GS, Pinto CS, Antunes PE, Antunes MJ.
Eur J Cardiothorac Surg. 2012;42:826-31.
A possible role for oxidation stress in lymphoid leukaemias and therapeutic failure.
Sarmento-Ribeiro AB, Proença MT, Sousa I, Pereira A, Guedes F, Teixeira A, Oliveira CR.
Leuk Res 2012, Apr; 36: 1041–1048.
A potential mechanism for the pathogenesis of psoriasis vulgaris.
Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
Int J Dermatol. 2012 Apr 18. doi: 10.1111/j.1365-4632.2011.05249.x. [Epub ahead of print] PubMed PMID: 22512275.
Applications of Tandem Mass Spectrometry (LC-MSMS) in estimating the post-mortem interval using the biochemistry of the vitreous humour.
Lendoiro E, Cordeiro C, Rodríguez-Calvo MS, Vieira DN, Suárez-Peñaranda JM, López-Rivadulla M, Muñoz-Barús JI.
Forensic Sci Int. 2012 Nov 30;223(1-3):160-4.
Astrocytic Adenosine A2A Receptors Control the Amyloid-β Peptide-Induced Decrease of Glutamate Uptake.
Matos M, Augusto E, Machado NJ, Dos Santos-Rodrigues A, Cunha RA, Agostinho P.
J Alzheimers Dis. 2012 Jan 1;31(3):555-67. PubMed PMID: 22647260.
Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner.
Bejarano E, Girao H, Yuste A, Patel B, Marques C, Spray DC, Pereira P, Cuervo AM.
Mol Biol Cell. 2012 Jun;23(11):2156-69.


Beat-to-beat systolic time-interval measurement from heart sounds and ECG.
Paiva RP, Carvalho P, Couceiro R, Henriques J, Antunes MJ, Quintal I, Muehlsteff J.
Physiol Meas 2012:33;177-94
Beta thalassemia major due to acquired uniparental disomy in a previously healthy adolescent.
Bento C, Maia TM, Milosevic JD, Carreira IM, Kralovics R, Ribeiro ML. Haematologica. 2012 Aug 8. [Epub ahead of print].
Biodistribution of lipid nanoparticles: a comparative study of pulmonary versus intravenous administration in rats.
Videira MA, Santos AC, Botelho MF.
Curr Radiopharm. 2012 Apr;5(2):158-65. Review.
PMID: 22280113 [PubMed - indexed for MEDLINE]
Blockade of adenosine A2A receptors prevents interleukin-1b-induced exacerbation of neuronal toxicity through a p38 MAPK pathway.
Simões, A.P., Duarte, J.A., Agasse, F., Canas, P.M., Tomé, A.R., Agostinho, P., Cunha, R.A. (2012)
Journal of Neuroinflammation 9, 204.


Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ mice.
Duarte JM, Agostinho PM, Carvalho RA, Cunha RA.
PLoS One. 2012;7(4):e21899. Epub 2012 Apr 13. PubMed PMID: 22514596; PubMed Central PMCID: PMC3326010.
Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder.
Pandolfo P, Machado NJ, Köfalvi A, Takahashi RN, Cunha RA.
Eur Neuropsychopharmacol. 2012 May 4. [Epub ahead of print] PubMed PMID: 22561003.
Calcium-permeable AMPA Receptors trigger neuronal NOS activation to promote nerve cell death in a Src kinase-dependent fashion.
R. Socodato, F. N. Santiago, C. C. Portugal, A. F. Domingues, A. R. Santiago, J. B. Relvas, A.F. Ambrósio, R. Paes-de-Carvalho.
J Biol Chem. 2012 Sep 19. [Epub ahead of print].
Can Biofluids Metabolic Profiling Help to Improve Healthcare during Pregnancy?
Gonçalo Graça, Sílvia O. Diaz, Joana Pinto, António S. Barros, Iola F. Duarte, Brian J. Goodfellow, Eulália Galhano, Cristina Pita, Maria do Céu Almeida, Isabel M. Carreira  and Ana M. Gil.
Spectroscopy: An International Journal  Volume 27 (2012), Issue 5-6, Pages 515-523.
Cardiac angiosarcoma in a pregnant woman: a case report and review of the literature.
Saraiva F, Antunes M, Providência LA.
Acta Cardiol. 2012 Dec;67(6):727-31.
Cardiac resynchronization therapy in the elderly: a realistic option for an increasing population?
António N, Elvas L, Gonçalves L, Providência LA.
Int J Cardiol. 2012 Feb 23;155(1):49-51
Cardiac troponin I: Prothrombotic risk marker in non-valvular atrial fibrillation.
Providência R, Paiva L, Faustino A, Botelho A, Trigo J, Casalta-Lopes J, Nascimento J, Leitão-Marques AM.
Int J Cardiol. 2012 Feb 19. [Epub ahead of print]
PMID: 22353438 [PubMed - as supplied by publisher]
CB1 receptor activation inhibits neuronal and astrocytic intermediary metabolism in the rat hippocampus.
Duarte, J.M., Ferreira, S.G., Carvalho, R.A., Cunha, R.A., Köfalvi, A. (2012)
Neurochemistry International 60, 1-8. 
Cerebral creatine deficiency syndromes.
Malheiro R, Diogo L, Garcia P, Fineza I, Oliveira G.
Acta Med Port. 2012 Nov-Dec;25(6):389-98.
Chemopreventive Efficacy of Atorvastatin against Nitrosamine-Induced Rat Bladder Cancer: Antioxidant, Anti-Proliferative and Anti-Inflammatory Properties.
Parada B, Reis F, Pinto A, Sereno J, Xavier-Cunha M, Neto P, Rocha-Pereira P, Mota A, Figueiredo A, Teixeira F.
Int J Mol Sci. 2012;13(7):8482-99.
Children’s Eating Attitudes Test: Psychometric Characteristics in a Portuguese Adolescent Sample.
Bento C, Pereira AT, Saraiva J, Marques M, Soares MJ, Bos S, Valente J, Azevedo MH, Macedo A ().
Revista de Psiquiatria Clínica 2012, 39(6): 189-93.
Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties.
Soares MI, Brito AF, Laranjo M, Paixão JA, Botelho MF, Pinho E Melo TM.
Eur J Med Chem. 2012 Nov 30;60C:254-262. doi: 10.1016/j.ejmech.2012.11.036. [Epub ahead of print]
PMID: 23313634 [PubMed - as supplied by publisher]
Churg-Strauss syndrome: case series.
Alfaro TM, Duarte C, Monteiro R, Simão A, Calretas S, Nascimento Costa JM.
Rev Port Pneumol. 2012 Mar;18(2):86-92. Epub 2012 Jan 11. English, Portuguese. PMID: 22240164
Celebrating the 10th anniversary of the portuguese cardiology data collection center: a reflexion on its past, present, and future.
Gonçalves LM, Seabra-Gomes R.
Rev Port Cardiol. 2012 Dec;31(12):763-768.
Cytotoxicity of ascorbic acid in a human colorectal adenocarcinoma cell line (WiDr): in vitro and in vivo studies.
Mamede AC, Pires AS, Abrantes AM, Tavares SD, Gonçalves AC, Casalta-Lopes JE, Sarmento-Ribeiro AB, Maia JM, Botelho MF.
Nutr Cancer. 2012;64(7):1049-57.
Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis.
Canhão H, Rodrigues AM, Mourão AF, Martins F, Santos MJ, Canas-Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araújo D, Silva C, Santos H, Duarte C, da Silva JA, Pimentel-Santos FM, Branco JC, Karlson EW, Fonseca JE, Solomon DH.
Rheumatology. 2012; 51: 2020-6.
Colangiocarcinoma Intra-hepático
Francisco Castro Sousa, Edgar Tavares Silva, José Guilherme Tralhão, Beatriz Costa, Mónica Martins, Marco Serôdio, Ricardo Martins 
Revista Portuguesa de Cirurgia (212) (23):33-42.
Compromised mitochondrial complex II in models of Machado-Joseph disease.
Laço MN, Oliveira CR, Paulson HL, Rego AC.Biochim Biophys Acta. 2012 Feb;1822(2):139-49.
Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose.
G.N. Costa, J. Vindeirinho, C. Cavadas, A.F. Ambrósio and P.F. Santos.
Mol Cell Neurosci. 2012, 50:113-123.
CoReumaPt Protocol: The Portuguese Cohort of Rheumatic Diseases.
Laires PA, Canhão H, Araújo D, Fonseca JE, Machado P, Mourão AF, Ramiro S, Romeu JC, Santos MJ, Silva I, Silva JA, Sousa E, Tavares V, Gouveia N, Branco JC.
Acta Reumatológica Portuguesa 2012; 37: 18-24.
Critical region in 2q31.2q32.3 deletion syndrome: Report of two phenotypically distinct patients, one with an additional deletion in alagille syndrome region.
Ferreira SI, Matoso E, Venâncio M, Saraiva J, Melo JB, Carreira IM. Mol Cytogenet. 2012 May 2;5:25. [Epub ahead of print]
Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration. Biochim Biophys Acta.
Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido A, Santos MS, Oliveira CR, Moreira PI.
2013 Jan 10. doi:pii: S0925-4439(13)00012-4. 10.1016/j.bbadis.2013.01.008
Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α.
Correia SC, Santos RX, Cardoso SM, Santos MS, Oliveira CR, Moreira PI.
Neurobiol Dis. 2012;45:206-218.
Cytotoxicity of ascorbic acid in a human colorectal adenocarcinoma cell line (WiDr): in vitro and in vivo studies.
Mamede AC, Pires AS, Abrantes AM, Tavares SD, Gonçalves AC, Casalta-Lopes JE, Sarmento-Ribeiro AB, Maia JM, Botelho MF.
Nutr Cancer. 2012;64(7):1049-57. doi: 10.1080/01635581.2012.713539. Epub 2012 Sep 13.
PMID: 22974001 [PubMed - in process]


Defects In Profile Rotary Nickel-Titanium Files After Clinical Use
M. M. Ferreira, H. D. Ferreira, B. Oliveiros, E. Carrilho
ENDO-Endodontic Practice Today. 2012:6(2):113-117.
Dexmedetomidine: current role in anesthesia and intensive care. Rev Bras Anestesiol.
Afonso J, Reis F.
2012 Jan-Feb;62(1):118-33. Review Article. PubMed PMID: 22248773.
Diabetes and Medicinal Plants in Portugal.
Ferreira F, Peixoto F, Seiça R, Santos MS.
In: Natural Product: Research Review. Ed.VK Gupta, Daya Publishing House, New Delhi, 2012 (Vol 1): 1-39.
Diabetes mellitus: new challenges and innovative therapies.
Sena C, Bento C, Pereira P, Marques F, Seiça R. In: New Strategies to Advance Pre/Diabetes Care: Integrative Aproach by PPPM. Ed.Mahmood Mozaffari, EPMA/Springer Book-Series, 2012.
Differential contribution of the guanylyl cyclase-cyclic GMP-protein kinase G pathway to the proliferation of neural stem cells stimulated by nitric oxide.
B.P. Carreira, M.I. Morte, A.S. Lourenço, A.I. Santos, A. Inácio, A.F. Ambrósio, C.M. Carvalho and I.M. Araújo. 
Neurosignals 2012 Feb 23 [Epub ahead of print]
Diffusion-weighted imaging of the liver: usefulness of ADC values in the differential diagnosis of focal lesions and effect of ROI methods on ADC measurements.
Filipe JP, Curvo-Semedo L, Casalta-Lopes J, Marques MC, Caseiro-Alves F.
MAGMA. 2012 Oct 6. [Epub ahead of print]
PMID: 23053714 [PubMed - as supplied by publisher]
Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice.
Pereira FC, Cunha-Oliveira T, Viana SD, Travassos AS, Nunes S, Silva C, Prediger RD, Rego AC, Ali SF, Ribeiro CA.
Neurotoxicol Teratol. 2012 Sep;34(5):522-9.
Distrofia muscular de emery-dreifuss: um caso clínico.
Saraiva F, Rodrigues D, Andrade H, Negrão L, Gonçalves L, Marinho A, Providência LA.
Rev Port Cardiol. 2012.


Editorial: Radiopharmaceuticals: pre-clinical evaluation.
Botelho MF.
Curr Radiopharm. 2012 Apr;5(2):76-8. No abstract available.
Effect of calcium hydroxide as intracanal medication on the apical sealing ability of MTA: an in vitro apexification model.
Tânia Afonso; Maria Lusitana Moura Pega; André Luiz Michelotto; Ana Margarida Abrantes; Bárbara Oliveiros; Eunice Virgínia Carrilho; Filomena Botelho; Manuel Marques Ferreira.
J Health Sci Inst. 2012;30(4):318-22
Effect of miR-34b overexpression on the radiosensitivity of non-small cell lung cancer cell lines.
Balça-Silva J, Sousa Neves S, Gonçalves AC, Abrantes AM, Casalta-Lopes J, Botelho MF, Sarmento-Ribeiro AB, Silva HC.
Anticancer Res. 2012 May;32(5):1603-9.
Epidemiology of Perinatal Depression in Portugal: Categorical and Dimensional Approach.
Maia BR, Marques M, Bos S, Pereira AT, Soares MJ, Valente J, Macedo A, Azevedo MHP.
Acta Médica Portuguesa; 24(S2): 443-448, 2012.
Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat.
J. Martins, M. Castelo-Branco, A. Batista, B. Oliveiros, A.R. Santiago, J. Galvão, E. Fernandes, F. Carvalho, C. Cavadas and A.F. Ambrósio.
PLoS One. 2011;6(12):e29583. Epub 2011 Dec 27.
Effect of miR-34b Overexpression on the Radiosensitivity of Non-small Cell Lung Cancer Cell Lines
Balça-Silva J, Neves SS, Gonçalves AC, Abrantes AM, Casalta-Lopes J, Botelho MF, Sarmento-Ribeiro AB, Silva HC. Anticancer Res 2012;32:1603-1609.
Elevated glucose concentration changes the content and cellular localization of AMPA receptors in the retina but not in the hippocampus.
A. F. Castilho, J. T. Liberal, F. I. Baptista, J. M. Gas
par, A. L. Carvalho, A.F. Ambrósio.
Neuroscience. 2012, 219:23-32.
Endoplasmic reticulum stress: a new playER in tauopathies.
Ferreiro E., Pereira C. (2012).
J Pathol 226:687-92 (invited commentary)
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers. Costa RO, Lacor PN, Ferreira IL, Resende R, Auberson YP, Klein WL, Oliveira CR, Rego AC, Pereira CM. Aging Cell. 2012 Jun 18. doi: 10.1111/j.1474-9726.2012.00848.x. [Epub ahead of print]
Epidemiology of Perinatal Depression in Portugal: Categorical and Dimensional Approach.
Maia BR, Marques M, Bos S, Pereira AT, Soares MJ, Valente J, Macedo A, Azevedo MHP.
Acta Médica Portuguesa; 24(S2): 443-448, 2012
Epigenetic regulation of BACE1 in Alzheimer’s disease patients and in transgenic mice.
Marques S.C.F., Lemos R., Ferreiro E., Martins M., de Mendonça A., Santana I., Outeiro T.F., Pereira CMF.2012 Sep 18;220:256-66. Epub 2012 Jun 21.(in press) Neuroscience.
Erythroid disturbances before and after treatment of Portuguese psoriasis vulgaris patients: a cross-sectional and longitudinal study.
Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
Am J Clin Dermatol. 2012 Feb 1;13(1):37-47. PubMed PMID: 21888450.
ESC Working Group on Valvular Heart Disease Position Paper: assessing the risk of interventions in patients with valvular heart disease.
Rosenhek R, Iung B, Tornos P, Antunes MJ, Prendergast BD, Otto CM, Kappetein AP, Stepinska J, Kaden JJ, Naber CK, Acartürk E, Gohlke-Bärwolf C.
Eur Heart J. 2012;33:822-8,
Estrogen receptor ligands for targeting breast tumours: a brief outlook on radioiodination strategies.
Oliveira MC, Neto C, Gano L, Marques F, Santos I, Thiemann T, Santos AC, Botelho F, Oliveira CF.
Curr Radiopharm. 2012 Apr;5(2):124-41. Review.
PMID: 22280114 [PubMed - indexed for MEDLINE]
Evaluation of an anorganic bovine-derived mineral with P-15 hydrogel bone graft: preliminary study in a rabbit cranial bone model.
Matos S, Guerra F, Krauser JT, Figueiredo H, Marcelino JP, Sanz M.
Evaluation of Dentin Formed In Autogenous Tooth Transplantation In Dog: A Comparision Between One And Two-Stage Surgical Techniques
Ferreira MM, Botelho MF, Carvalho L, Oliveiros B, Carrilho EVP
Dental Traumatology. 2012; 28:97-100.
Exercise-induced pulmonary hypertension in scleroderma patients: a common finding but with elusive pathophysiology.
Baptista R, Serra S, Martins R, Salvador MJ, Castro G, Gomes M, Santos L, Monteiro P, da Silva JA, Pêgo M. Echocardiography. 2012 Dec 18. doi: 10.1111/echo.12063 


Farnesyltransferase inhibitors: molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition.
4. Costa CB, Casalta-Lopes J, Andrade C, Moreira D, Oliveira A, Gonçalves AC, Alves V, Silva T, Dourado M, Nascimento-Costa JM, Sarmento-Ribeiro AB.
Anticancer Res 2012 Mar; 32(3): 831-838.
Forensic evidence against torture.
Vieira DN.
Torture. 2012;22 Suppl 1:1-4.
Foxp3 expression is required for the induction of therapeutic tissue tolerance.
Regateiro FS, Chen Y, Kendal AR, Hilbrands R, Adams E, Cobbold SP, Ma J, Andersen KG, Betz AG, Zhang M, Madhiwalla S, Roberts B, Waldmann H, Nolan KF, Howie D.
J Immunol. 2012 Oct 15;189(8):3947-56. doi: 10.4049/jimmunol.1200449. Epub 2012 Sep 17.
Functional characterization of peripheral blood dendritic cells and monocytes in systemic lupus erythematosus.
Henriques A, Inês L, Carvalheiro T, Couto M, Andrade A, Pedreiro S, Laranjeira P, Morgado JM, Pais ML, da Silva JAP, Paiva A. Rheumatology International 2012; 32:863-9.
Functional interaction between presynaptic α6β2-containing nicotinic and adenosine A<sub>2A</sub> receptors in the control of dopamine release in the rat striatum.
Garção P, Szabó EC, Wopereis S, Castro AA, Tomé AR, Prediger RD, Cunha RA, Agostinho P, Köfalvi A.
Br J Pharmacol. 2013 (in press)
Functional parcellation of the operculo-insular cortex in perceptual decision making: an fMRI study.
Rebola J, Castelhano J, Ferreira C, Castelo-Branco M.
Neuropsychologia. 2012;50(14):3693-70


Genetic Overlap of Schizophrenia and Bipolar Disorder in a High-Density Linkage Survey in the Portuguese Island Population.
Ayman H. Fanous, Frank A. Middleton, Karen Gentile, Richard L. Amdur, Brion S. Maher, Zhongming Zhao, Jingchun Sun, Helena Medeiros, Celia Carvalho, Susana R. Ferreira, Antonio Macedo, James A. Knowles, Maria H. Azevedo, Michele T. Pato, and Carlos N. Pato.
(2012).AMERICAN JOURNAL OF MEDICAL GENETICS, PART B: Neuropsychiatric Genetics, Volume 159B, Issue 4, Pages 383-391.
Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?
Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Williams S.
Int J Alzheimers Dis. 2012;2012:276803.
Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).
Vahanian A, Alfieri O, Andreotti F, Antunes MJ, et al.
Eur Heart J 2012;33:2451-2496


Heme oxygenase-1 protects retinal endothelial cells against high glucose- and oxidative/nitrosative stress-induced toxicityPLoS One.
A. F. Castilho, C. A. Aveleira, E. C. Leal, N. F. Simões, C. R. Fernandes, R. I. Meirinhos, F. I. Baptista, A.F. Ambrósio.
2012;7(8):e42428. Epub 2012 Aug 3.
Hemoglobina: um mero valor analítico ou um poderoso preditor de risco em doentes com sindromes coronárias agudas?
Ferreira M, António N, Gonçalves F, Monteiro P, Gonçalves L, Freitas M, Providência LA.
Rev Port Cardiol. 2012 31;2:121-131. (Com Editorial).
Hepatic extraction fraction: interest of its quantification in patients with hepatic tumours.
Tralhão JG, Abrantes AM, Hoti E, Cardoso D, Figueirinha R, Botelho MF, Castro-Sousa F.
Hepatogastroenterology. 2012 Jul-Aug;59(117):1507-11. doi: 10.5754/hge10074.
Hepatocellular Carcinoma and Chemotherapy: The Role of p53.
Brito AF, Abrantes AM, Pinto-Costa C, Gomes AR, Mamede AC, Casalta-Lopes J, Gonçalves AC, Sarmento-Ribeiro AB, Tralhão JG, Botelho MF.
Chemotherapy. 2012 Dec 21;58(5):381-386. [Epub ahead of print]
High resolution melting: improvements in the genetic diagnosis of hypertrophic cardiomyopathy in a Portuguese cohort. 
Santos S, Marques V, Pires M, Silveira L, Oliveira H, Lança V, Brito D, Madeira H, Esteves JF, Freitas A, Carreira IM, Gaspar IM, Monteiro C, Fernandes AR.
BMC Med Genet 2012; 13:17.
Human periprostatic adipose tissue promotes prostate cancer aggressiveness in vitro.
Ribeiro R, Monteiro C, Cunha V, Oliveira MJ, Freitas M, Fraga A, Príncipe P, Lobato C, Lobo F, Morais A, Silva V, Sanches-Magalhães J, Oliveira J, Pina F, Mota-Pinto A, Lopes C, Medeiros R. J Exp Clin Cancer Res. 2012 Apr 2;31(1):32.


Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance.
Cardoso S, Santos RX, Correia SC, Carvalho C, Santos MS, Baldeiras I, Oliveira CR, Moreira PI.
Neurobiol Dis. 2013;49:1-12.
Insulin in central nervous system: more than just a peripheral hormone. Duarte AI, Moreira PI, Oliveira CR.
J Aging Res 2012;2012:384017.
Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer’s disease and diabetes interrelation.
Correia SC, Santos RX, Carvalho C, Cardoso S, Candeias E, Santos MS, Oliveira CR, Moreira PI.
Brain Res. 2012;1441:64-78.
Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial derived nitric oxide.
Pires A, Pinho M, Sena CM, Seiça R, Leite-Moreia A.
Am J Physiol Heart Circ Physiol, 2012; 302: H1131-H1137.
Intracardiac aorto-right atrial tunnel.
Pancas R, Coutinho GF, Antunes MJ.
Eur J Cardiothorac Surg. 2012;42:376.
Inv21p12q22del21q22 and intellectual disability.
Oliveira R, Dória S, Madureira C, Lima V, Almeida C, Pinho MJ, Ramalho C, Matoso E, Barros A, Carreira IM, Moura CP.
Gene 2013, 15;517(1):120-4.


Juvenile polyposis of infancy in a child with deletion of BMPR1A and PTEN genes: Surgical approach.
Oliveira PH, Cunha C, Almeida, Ferreira R, Maia S, Saraiva JM, Lopes MF.
J Pediatr Surg 2013;48:E33–E37


Left atrial reservoir phase – deformation analysis.
Teixeira R, Vieira M, Gonçalves L.
Eur Heart J Cardiovasc Imaging. 2012. Doi:10.1093/ehjci/jes316
Limas Endodônticas: Esterilizar Ou Descartar?
Ferreira MM, Michelotto ALC, Alexandre AR, Morganho R, Carrilho EVP.
Endod. 2012; Jan-Mar 2(1):46-51.
Liver hepcidin mRNA expression is inappropriately low in alcoholic patients compared with healthy controls Costa-Matos L, Batista P, Monteiro N, Simões M, Egas C, Pereira J, Pinho H, Santos N, Ribeiro J, Cipriano MA, Henriques P, Girão F, Rodrigues A, Carvalho A.
Eur J Gastroenterol Hepatol. 2012 Oct;24(10):1158-65.


Main determinants of PON1 activity in hemodialysis patients.
Ribeiro S, do Sameiro Faria M, Mascarenhas-Melo F, Freitas I, Mendonça MI, Nascimento H, Rocha-Pereira P, Miranda V, Mendonça D, Quintanilha A, Belo L, Costa E, Reis F, Santos-Silva A.
Am J Nephrol. 2012;36(4):317-23.
Maxillary overlay removable partial dentures for the restoration of worn teeth.
Fonseca J, Nicolau P, Daher T.
Inside Dental Technology, January 2012, Pages 2-10.
Mean pulmonary arterial pressure after percutaneous mitral valvuloplasty predicts long-term adverse outcomes.
Jorge E, Baptista R, Faria H, Calisto J, Matos V, Gonçalves L, Monteiro P, Providência LA.
Rev Port Cardiol. 2012;31(1):19-25.
Mechanism of inhibition of mitochondrial ATP synthase by 17β-Estradiol. 
Moreno AJ, Moreira PI, Custódio JB, Santos MS. 
J Bioenerg Biomembr. 2012 Dec 29.
Mediastinal masses: case séries.
Monteiro R, Alfaro TM, Correia L, Simão A, Cordeiro CR, Carvalho A, Costa JN.
Acta Med Port. 2011 Nov;24(6):899-904. Epub 2012 Feb 20. Portuguese. PMID: 22713183.
Metabolic alterations induced by sucrose intake and Alzheimer’s disease promote similar brain mitochondrial abnormalities.
Carvalho C, Cardoso S, Correia SC, Santos RX, Santos MS, Baldeiras I, Oliveira CR, Moreira PI.
Diabetes. 2012;61:1234-1242.
Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.
Gonçalves J, Baptista S, Olesen MV, Fontes-Ribeiro C, Malva JO, Woldbye DP, Silva AP.
J Neurochem. 2012 Dec;123(6):1041-53
Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells.
T. Martins, T. Burgoyne, B. A. Kenny, N. Hudson, C. E. Futter, A.F. Ambrósio, A P. Silva, J. Greenwood, P. Turowski.
Neuropharmacology. 2012 Sep 1. [Epub ahead of print].
Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity.
Matafome P, Santos-Silva D, Crisóstomo J, Rodrigues T, Rodrigues L, Sena C, Pereira P, Seiça R.
Arch Physiol Biochem, 2012; 118: 58-68.
Methylglyoxal promotes oxidative stress and endothelial dysfunction.
Sena C, Matafome P, Crisóstomo J, Rodrigues L, Fernandes R, Pereira P, Seiça R.
Pharmacol Res, 2012; 2012: 497-506.
Methylglyoxal, obesity and diabetes.
Matafome P, Sena C, Seiça R.
Endocrine, 2012. [Epub ahead of print].
Microbial quality and yeast population dynamics in cracked green table olives’ fermentations.
Alves Maria, Gonçalves Teresa, Quintas Célia.
Food Control 23 (2012) 363-368.
Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease.
Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. 
Curr Alzheimer Res. 2012 Oct 9.
Mitochondrial-and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.
Ferreiro E., Baldeiras I., Ferreira I., Costa R.O., Rego A.C., Pereira C., Oliveira C.R. (in press).
Int J Cell Biol. (review) Int J Cell Biol. 2012;2012:735206. Epub 2012 Jun 4.
Mitochondrial DNA 8993T>G mutation in a child with OTC deficiency and Leigh syn drome- an unexpected association.
Henriques M, Diogo L, Garcia P, Pratas J, Simões M, Grazina M (2012).J Child Neurol. 2012 Jan 12. [Epub ahead of print].
Mitochondrial Respiratory Chain: Biochemical Analysis and Criterion for Deficiency in Diagnosis. In Mitochondrial disorders: Methods and Protocols.
Grazina M (2012). Edited by Lee-Jun C. Wong.
Chap 6. Humana Press. New York. Methods Mol Biol; 837:73-91.
Multivariate pattern analysis reveals subtle brain anomalies relevant to the cognitive phenotype in neurofibromatosis type 1.
Duarte JV, Ribeiro MJ, Violante IR, Cunha G, Silva E, Castelo-Branco M.
Hum Brain Mapp. 2012 Sep 11


Nanoparticles, nanotechnology and pulmonary nanotoxicology.
A.J. Ferreira, J. Cemlyn-Jones, C. Robalo Cordeiro
Centre of Pneumology, Coimbra University Medical School, Coimbra, Portugal
Received 9 April 2012; accepted 25 September 2012
Neonatal liver failure due to deoxyguanosine kinase deficiency.
Nobre S, Grazina M, Silva F, Gonçalves I, Garcia P, Veiga C, Cipriano A, Diogo L. 2012.
BMJ Case Rep. Apr 2; DOI: 10.1136/bcr.12.2011.5317.
Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.
Baptista S, Bento AR, Gonçalves J, Bernardino L, Summavielle T, Lobo A, Fontes-Ribeiro C, Malva JO, Agasse F, Silva AP.
Neuropharmacology. 2012 Jun;62(7):2413-23. Epub 2012 Feb 22.
Nitric oxide modulates sodium vitamin C transporter 2 (SVCT-2) expression via protein kinase G (PKG) and nuclear factor-κB (NF-κB).
C.C. Portugal, T.G. Encarnacao, R. Socodato, S.R. Moreira, D. Brudzewsky, A.F. Ambrósio and R. Paes-de-Carvalho.
J Biol Chem. 2012, 287:3860-3872.
Nonketotic hyperglycinemia – a cause of encephalopathy in children.
Veríssimo C, Garcia P, Simões M, Robalo C, Henriques R, Diogo L, Grazina M (2012).
J Child Neurol; 27(8):1059 - 1061. DOI 10.1177/0883073811431015.
Non-syndromic Sensorineural Prelingual Deafness: The Importance of Genetic Counseling in Demystifying Parents’ Beliefs About the Cause of Their Children’s Deafness.
Rodrigues F, Paneque M, Reis C, Venâncio M, Sequeiros J, Saraiva J.
J Genet Counsel DOI 10.1007/s10897-012-9565-z
Nuclear and mitochondrial DNA oxidation in Alzheimer disease.
Santos RX, Correia SS, Zhu X, Lee HG, Petersen RB, Nunomura A, Perry G, Smith MA, Moreira PI.
Free Radic Res. 2012;46:565-756.


Organizing pneumonia due to actinomycosis: an undescribed association.

Alfaro TM, Bernardo J, Garcia H, Alves F, Carvalho L, Caseiro Alves F, Robalo Cordeiro C. Respiration. 2011;81(5):433-6. Epub 2010 Nov 5. PMID: 21051872.

Outcomes of choledochal cysts with or without intrahepatic involvement in children after extrahepatic cyst excision and Roux-en-Y hepaticojejunostomy.
Congo K, Lopes MF, Oliveira PH, Matos H, Basso S, Reis A.Ann Hepatol. 2012 Jul;11(4):536-43.
Overlap between asthma and COPD.
Alfaro TM, Freitas SD, Cordeiro CR.J Bras Pneumol. 2012 Dec;38(6):813-816. English, Portuguese. No abstract available. PMID: 23288131
Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase.
Freitas M, Baldeiras I, Proença T, Alves V, Mota-Pinto A, Sarmento-Ribeiro A. FEBS Open Bio 2012;2:119–128.


Pharmacogenetics in Latin American populations: regulatory aspects, application to herbal medicine, cardiovascular and psychiatric disorders.
Rodeiro I, Remírez-Figueredo, García-Mesa M, Dorado P, LLerena A, and CEIBA.
FP Consortium of the Ibero-American Network of Pharmacogenetics and Pharmacogenomics RIBEF (2012).
Drug Metab Drug Interact. 2012;27(1):57-60. DOI: 10.1515/dmdi-2012-0006.34.
Phenotypic and functional alterations on inflammatory peripheral blood cells after acute myocardial infarction.
Carvalheiro T, Velada I, Valado A, Mendes F, Martinho A, António N, Gonçalves L, Providência LA, Pais ML, Paiva A. J Cardiovasc Trans Res 2012; 5(3):309-20
Portuguese validation of the Children’s Eating Attitudes Test.
Teixeira MCB, Pereira ATF, Saraiva JM, Marques M, Soares MJ, Bos SC, Valente J, Azevedo MHP, Macedo AJF. Rev Psiq Clin 2012;39:189-193
Presynaptic CB(1) cannabinoid receptors control frontocorticalserotonin and glutamate release - Species differences.
Ferreira SG, Teixeira FM, Garção P, Agostinho P, Ledent C, Cortes L, Mackie K,Köfalvi A. Neurochem Int. 2012 Jul;61(2):219-26. Epub 2012 May 17. PubMed PMID: 22609378; PubMed Central PMCID: PMC3408788.
Prevalence of asthma in Portugal - The Portuguese National Asthma Survey.
Sa-Sousa A, Morais-Almeida M, Azevedo LF, Carvalho R, Jacinto T, Todo-Bom A, Loureiro C, Bugalho-Almeida A, Bousquet J, Fonseca JA.
Clin Transl Allergy. 2012 Aug 29;2(1):15.
Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathway.
Coelho-Santos V, Gonçalves J, Fontes-Ribeiro C, Silva AP.J Neuroinflammation. 2012 Jul 6;9:103.
Progressive changes in pneumococcal carriage in children attending daycare in Portugal after 6 years of gradual conjugate vaccine introduction show falls in most residual vaccine serotypes but no net replacement or trends in diversity.
Rodrigues F, Foster D, Caramelo F, Serranho P, Gonçalves G, Januário L, Finn A. Vaccine. 2012 Jun 6;30(26):3951-6. doi: 10.1016/j.vaccine.2012.03.058. Epub 2012 Apr 3
Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model.
Gonçalves A, Leal E, Paiva A, Teixeira Lemos E, Teixeira F, Ribeiro CF, Reis F, Ambrósio AF, Fernandes R.
Diabetes Obes Metab. 2012 May;14(5):454-63.
doi: 10.1111/j.1463-1326.2011.01548.x. Epub 2012 Jan 6. PubMed PMID: 22151893.
Protective Y Y(2) receptors in cell death and microglial response role of neuropeptide following methamphetamine injury.
Gonçalves J, Ribeiro CF, Malva JO, Silva AP.Eur J Neurosci. 2012 Jul 17. doi: 10.1111/j.1460-9568.2012.08232.x. [Epub ahead of print]
Pseudophasic cystoid macular edema.
Lobo C.
Ophthalmologica. 2012;227(2):61-7. doi: 10.1159/000331277. Epub 2011 Sep 15. Review.
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Pulmonary dissection during diagnostic pulmonary angiography.
Baptista R, Castro G, da Silva AM, Providência LA.
Rev Port Cardiol. 2012 Jun;31(6):465.


Radiopharmaceuticals for bone metastasis therapy and beyond: a voyage from the past to the present and a look to the future.
Ferreira S, Dormehl I, Botelho MF. Cancer Biother Radiopharm. 2012 Nov;27(9):535-51. doi: 10.1089/cbr.2012.1258. Epub 2012 Oct 17. PMID: 23075374 [PubMed - in process]
Radiolabelling of ascorbic acid: a new clue to clarify its action as an anticancer agent?
Mamede AC, Abrantes AM, Pires AS, Tavares SD, Serra ME, Maia JM, Botelho MF. Curr Radiopharm. 2012 Apr;5(2):106-12. PMID: 22280108 [PubMed - indexed for MEDLINE]
Rare Anatomical Variation of Absence of the Sciatic Nerve: Completely Substituted by the Tibial and Common Fibular Nerve.
Coelho P, Melo C, Bernardes A.
Acta Med Port. 2013 May-Jun,26(3):283-286
Recommendation to include methylisothiazolinone in the European baseline patch test series - on behalf of the European Society of Contact Dermatitis and the European
Environmental and Contact Dermatitis Research Group Bruze, M, Engfeldt, M, Goncalo, M, Goossens, A
Contact Dermatitis, 69 (5):263-270
Recto-anal manometric characteristics of type 2 diabetic patients who have sensation of incomplete defecation.
Jorge JX, Borges CI, Panão EA, Delgado FJ, Simões MA, Coelho AC, Silva AL, Almeida CC.
J Diabetes Complications. 2013 Jan 8.
Reduced elastogenesis: a clue to the arteriosclerosis and emphysematous changes in Schimke immuno-osseous dysplasia?
Morimoto M, Yu Z, Stenzel P, Clewing JM, Najafian B, Mayfield C, Hendson G, Weinkauf JG, Gormley AK, Parham DM, Ponniah U, André JL, Asakura Y, Basiratnia M, Bogdanovi 263 R, Bokenkamp A, Bonneau D, Buck A, Charrow J, Cochat P, Cordeiro I, Deschenes G, Fenkçi MS, Frange P, Fründ S, Fryssira H, Guillen-Navarro E, Keller K, Kirmani S, Kobelka C, Lamfers P, Levtchenko E, Lewis DB, Massella L, McLeod DR, Milford DV, Nobili F, Saraiva JM, Semerci CN, Shoemaker L, Staji 263 NA, Stein A, Taha D, Wand D, Zonana J, Lücke T, Boerkoel CF 3rd.
Orphanet J Rare Dis. 2012;7:70.
Reduction of methylglyoxal-induced glycation by pyridoxamine improves adipose tissue microvascular lesions.
Rodrigues T, Matafome P, Santos-Silva D, Sena C, Seiça R.
J Diabetes Res. 2013;2013:690650.
Regular Physical Exercise as a Strategy to Improve Antioxidant and Anti-Inflammatory Status: Benefits in Type 2 DiabetesMellitus.
Teixeira-Lemos E, Oliveira J, Páscoa-Pinheiro J, Reis F.
Oxidative Med & Cellular Longevity 2012; 2012: 741545, 15 pages. Review Article.
Relationships Between Rhinitis Symptoms, Respiratory Viral Infections and
Nasopharyngeal Colonization With Streptococcus pneumoniae, Haemophilus
influenzae and Staphylococcus aureus in Children Attending Daycare.

Rodrigues F, Foster D, Nicoli E, Trotter C, Vipond B, Muir P, Gonçalves G, Januário L, Finn A.
Pediatr Infect Dis J. 2013;32(3):227-232.
Response to Yusuf and Watson.
Miguel AI, Henriques F, Azevedo LF, Loureiro AJ, Maberley DA.
Eye . 2013 (in press)
Rest myocardial perfusion imaging: a valuable tool in ED.
Ferreira MJ, Cunha MJ, Albuquerque A, Moreira AP, Costa G, Lima J, Pego M.
Am J Emerg Med. 2013 Oct 22
Retinal gene therapy with a large MYO7A cDNA using adeno-associated virus.
Lopes VS, Boye SE, Louie CM, Boye S, Dyka F, Chiodo V, Fofo H, Hauswirth WW, Williams DS.
Gene Ther. 2013 Jan 24. doi: 10.1038/gt.2013.3.
Retinol and retinyl palmitate in foetal lung mice: sexual dimorphism.
Carvalho O, Gonçalves C.
Crit Care Res Pract. 2013;2013:760305. doi: 10.1155/2013/760305. Epub 2013 Jan 13.
Reverse myocardial effects of intermedin in pressure overloaded rats: role of endothelial nitric oxide synthase activity.
Pires A, Pinho M, Alves B, Pinho S, Sena CM, Seiça R, Leite-Moreia A.
J Physiol, 2012 [Epub ahead of print]
Revisiting Thyroid Hormones in Schizophrenia.
Nadine Correia Santos, Patrício Costa, Dina Ruano, António Macedo, Maria João Soares, José Valente, Ana Telma Pereira, Maria Helena Azevedo and Joana Almeida Palha (2012).Journal of Thyroid Research; Volume 2012, Article ID 569147, 1-15.
Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study
do Sameiro-Faria M, Ribeiro S, Costa E, Mendonca D, Teixeira L, Rocha-Pereira P, Fernandes J, Nascimento H, Kohlova M, Reis F, Amado L, Bronze-da-Rocha E, Miranda V, Quintanilha A, Belo L, Santos-Silva A.
Disease markers, 791-798, 10.1155/2013/518945 2013
Rupture of splenic angiosarcoma: a rare cause of spontaneous. haemoperitoneum. Alexandrino H, Julião MJ, Tralhão JG, Castro-Sousa F
BMJ case rep 2013. Dói:10.1136/br-2013-009748


Severe tricuspid regurgitation after traumatic papillary muscle rupture.
Correia PM, Coutinho GF, Antunes MJ.
Eur J Cardiothorac Surg. 2012 May;41:e128.
Sex selection and assisted reproduction technologies.
Silvestre M.
Lex Med. 2012, 9(17):157-163.
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.
Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhão JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L.
Sci Signal. 2011 Nov 15;4(199).
Short forms of the postpartum depression screening scale: as accurate as the original form.
Pereira AT, Bos S, Marques M, Maia B, Soares M., Valente J, AP, Nogueira V, Azevedo MH, Macedo A.
Archives of Women’s Mental Health 2013,16(1):67-77. Factor de impacto: 2.057 (ISI – Journal Citation Report)
Socio-demographic characteristics and quality of life of elderly patients with hypertension who live in Portugal: a community pharmacy study
Silva ES, Ribeiro O, Ponciano E, Caramona M
International Journal of Clinical Pharmacy, 35 (6):1276-1277, Dec 2013
Study of perioperative liver function by dynamic monitoring of ICG-clearance.
Tralhao JG, Hoti E, Oliveiros B, Botelho MF, Sousa FC.
Hepatogastroenterology. 2012 Jun;59(116):1179-83. doi: 10.5754/hge09726.
Synthesis of new 2-galactosylthiazolidine-4-carboxylic acid amides. Antitumor evaluation against melanoma and breast cancer cells.
Serra AC, Rocha Gonsalves AM, Laranjo M, Abrantes AM, Gonçalves AC, Sarmento-Ribeiro AB, Botelho MF. Eur J Med Chem. 2012 Jul;53:398-402. doi: 10.1016/j.ejmech.2012.04.003. Epub 2012 Apr 13. PMID: 22560315 [PubMed - indexed for MEDLINE]


Thermolabile liposomes: a controlled release delivery tool in diagnosis/therapy in experimental pulmonary ɶdema.
Santos AC, Matos CM, Oliveiros B, Almeida T, Gano L, Neves M, Ferreira N. Curr Radiopharm. 2012 Apr;5(2):166-74. Review. PMID: 22280109 [PubMed - indexed for MEDLINE]
Th17 Cells in systemic lupus erythematosus share functional features with Th17 cells from normal bone marrow and peripheral tissues.
Henriques A, Inês L, Pais ML, da Silva JAP, Paiva AA. Clinical Rheumatology 2012; 31:483-91. (Epub2011 Oct 26)
Th17 cells induce a distinct graft rejection response that does not require IL-17A.
Agorogiannis EI, Regateiro FS, Howie D, Waldmann H, Cobbold SP.
Am J Transplant. 2012 Apr;12(4):835-45. doi: 10.1111/j.1600-6143.2011.03971.x. Epub 2012 Mar 5
The five most important questions on TAVI: the surgeons view. An interdisciplinary debate initiated by.
Antunes MJ, Kappetein P, Lange R, Wendler O.
EuroIntervention 2012;7:0-0.
The latest news about the escel platform.
Jean Fajadet , Gonçalves L, Martine Gilard.
EuroIntervention 2012 ;25;8(4):427-8
The need for transparency and good practices in the qPCR literature
Bustin, SA, Benes, V, Garson, J, Hellemans, J, Huggett, J, Kubista, M,
Mueller, R, Nolan, T et al.
NATURE METHODS, 10 (11):1063-1067, 10.1038/nmeth.2697 NOV 2013
The role of perfectionism in postpartum depression and symptomatology.
Maia BR, Pereira AT, Marques M, Bos S, Soares MJ, Valente J, Gomes AA, Azevedo MH, Macedo A.
Archives of Women's Mental Health;  2012, DOI: 10.1007/s00737-012-0310-2 . [Epub ahead of print]
Tolerogenic versus inflammatory activity of peripheral blood monocytes and dendritic cells subpopulations in systemic lupus erythematosus.
Tiago Carvalheiro, Ana Rodrigues, Ana Lopes, Luís Inês, Isabel Velada,Andreia Ribeiro, António Martinho, José A. P. Silva, Maria L. Pais, and Artur Paiva.
Clinical and Developmental Immunology 2012;2012:934161. doi: 10.1155/2012/934161. Epub 2012 Aug 30.
Tromboembolia pulmonar de risco elevado com trombos da cavidade auricular direita.
Saraiva F, Fonseca I, Martins R, Gonçalves L, Providência LA.
Rev Port Cardiol. 2012;31(5):399-400.
Two-dimensional segmentation of the retinal vascular network from optical coherence tomography
Rodrigues, P, Guimaraes, P, Santos, T, Simao, S, Miranda, T, Serranho,
P, Bernardes, R
Journal of Biomedical Optics, 18 (12):10.1117/1.jbo.18.12.126011 dec 2013
Tumour hypoxia and technetium tracers: in vivo studies.
Abrantes AM, Serra E, Goncalves C, Oliveiros B, Laranjo M, Sarmento-Ribeiro AB, Rocha-Gonsalves A, Botelho MF. Curr Radiopharm. 2012 Apr;5(2):99-105. PMID: 22280110 [PubMed - indexed for MEDLINE]


Ubiquitin-Proteasome System Impairment and MPTP-Induced Oxidative Stress in the Brain of C57BL/6 Wild-type and GSTP Knockout Mice.
Carvalho AN, Marques C, Rodrigues E, Henderson CJ, Wolf CR, Pereira P, Gama MJ. Mol Neurobiol. 2013 Apr;47(2):662-72.
UPLC-MS/MS determination in blood of a mixed-drug fatal intoxication: A case report.
Proença P, Franco JM, Murta C, Monteiro C, Costa J, Corte-Real F, Vieira DN.
Forensic Sci Int. 2012 Nov 15. doi:pii: S0379-0738(12)00492-6.
UPLC-MS metabolic profiling of second trimester amniotic fluid and maternal urine and comparison with NMR spectral profiling for the identification of pregnancy disorder biomarkers.
Graça G, Goodfellow BJ, Barros AS, Diaz S, Duarte IF, Spagou K, Veselkov K, Want EJ, Lindon JC, Carreira IM, Galhano E, Pita C, Gil AM.
Mol Biosyst. 2012 Apr;8(4):1243-54.


Validation of a dental image-analyzer tool to measure the radiographic defect angle of the intrabony defect in periodontitis patients.
Moutinho RP, Coelho L, Silva A, Lobo Pereira JA, Pinto M, Baptista IP.
J Periodontal Res. 2012 Dec;47(6):695-700. doi: 10.1111/j.1600-0765.2012.01483.x. Epub 2012 Apr 27.
PMID:22537145 [PubMed - in process]
Vascular access versus the effect of statins on inflammation and fibrinolysis in renal dialysis patients
Faria, MD, Ribeiro, S, Rocha-Pereira, P, Miranda, V, Quintanilha, A,
Reis, F, Costa, E, Belo, L, Santos-Silva, A
Journal of Vascular Access, 14 (4):335-341, 10.5301/jva.5000132 Oct-Dec 2013