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Artigos publicados pela FMUC em Revistas com Factor de Impacto e indexadas na Web of Science

A beta and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

Ferreira, IL; Ferreiro, E; Schmidt, J; Cardoso, JM; Pereira, CMF; Carvalho, AL; Oliveira, CR; Rego, AC

NEUROBIOLOGY OF AGING, 36 (2):680-692;FEB 2015

A New Approach to Assess Early Progressive Loss Across Multiple Visual Channels In the Natural History of Glaucoma.

Mateus C, Raimundo M, Oliveiros B, Faria P, Reis A, Castelo-Branco M.

J Glaucoma. 2015 Jan 30

A technique to remove a stable all-polyethylene cemented acetabular liner in revision hip arthroplasty: A case report.

Judas FM, Lucas FM, Fonseca RL.

Int J Surg Case Rep. 2015 Feb 18;9C:54-56.

Abnormal relationship between GABA, neurophysiology and impulsive behavior in neurofibromatosis type 1

Ribeiro, MJ; Violante, IR; Bernardino, I; Edden, RAB; Castelo-Branco, M

CORTEX, 64 194-208; 10.1016/j.cortex.2014.10.019 MAR 2015

Adenosine A(2b) receptors control A(1) receptor-mediated inhibition of synaptic transmission in the mouse hippocampus

Goncalves, FQ; Pires, J; Pliassova, A; Beleza, R; Lemos, C; Marques, JM; Rodrigues, RJ; Canas, PM; Kofalvi, A; Cunha, RA; Rial, D

European Journal of Neuroscience, 41 (7):876-886; 10.1111/ejn.12851 APR 2015

Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure.

Madeira MH, Elvas F, Boia R, Gonçalves FQ, Cunha RA, Ambrósio AF, Santiago AR.

J Neuroinflammation. 2015 Jun 10;12:115

Adenosine A3 receptor activation is neuroprotective against retinal neurodegeneration.

Galvao J, Elvas F, Martins T, Cordeiro MF, Ambrósio AF, Santiago AR.

Exp Eye Res. 2015 Nov;140:65-74

Age-Dependent Biochemical Dysfunction in Skeletal Muscle of Triple-Transgenic Mouse Model of Alzheimer's Disease

Monteiro-Cardoso, VF; Castro, M; Oliveira, MM; Moreira, PI; Peixoto, F; Videira, RA

Current Alzheimer Research, 12 (2):100-115; 2015

Age-Related Macular Degeneration prevalence in Portugal: the Coimbra Eye Study - Report 2

Silva, R; Lains, I; Lobo, CF; Figueira, J; Ribeiro, L; Nunes, S; Veiga, P; Rodrigues, V; Cachulo, ML; Cunha-Vaz, JG

Investigative Ophthalmology & Visual Science, 56 (7): Jun 2015

Alterations on peripheral blood B cell subsets induced by allergic rhinitis

Henriques, A; Nunes, R; Loureiro, G; Martinho, A; Pais, M; Segorbe-Luis, A; Trindade, H; Pereira, C; Paiva, A

INFLAMMATION RESEARCH, 64 (3-4):145-149; APR 2015

Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers.

Carvalho C, Santos MS, Oliveira CR, Moreira PI.

Biochim Biophys Acta. 2015 May 7;1852(8):1665-1675

Alzheimer's Disease-Related Misfolded Proteins and Dysfunctional Organelles on Autophagy Menu

Correia, SC; Resende, R; Moreira, PI; Pereira, CM

DNA and Cell Biology, 34 (4):261-273; 10.1089/dna..2757 APR 1 2015

Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells

Fonseca, ACRG; Moreira, PI; Oliveira, CR; Cardoso, SM; Pinton, P; Pereira, CF

Molecular Neurobiology, 51 (2):610-622; 10.1007/s12035-014-8740-7 APR 2015

Analysis of organophosphorus pesticides in whole blood by GC-MS-mu ECD with forensic purposes

Valente, NIP; Tarelho, S; Castro, AL; Silvestre, A; Teixeira, HM

JOURNAL OF FORENSIC AND LEGAL MEDICINE, 33 28-34; 10.1016/j.jflm.2015.03.006 JUL 2015

Assessment of IrisPlex-based multiplex for eye and skin color prediction with application to a Portuguese population.

Dario P, Mouriño H, Oliveira AR, Lucas I, Ribeiro T, Porto MJ, Costa Santos J, Dias D, Corte Real F.

Int J Legal Med. 2015 Nov;129(6):1191-200.

Asthma control and exacerbations in patients with severe asthma treated with omalizumab in Portugal.

Sousa AS, Pereira AM, Fonseca JA, Azevedo LF, Abreu C, Arrobas A, Calvo T, Silvestre MJ, Cunha L, Falcão H, Drummond M, Geraldes L, Loureiro C; Severe Asthma Specialist Network (Rede de Especialistas de Asma Grave REAG).

Rev Port Pneumol (2006). 2015 Apr 16.

ATP as a multi-target danger signal in the brain

Rodrigues, RJ; Tome, A; Cunha, RA

FRONTIERS IN NEUROSCIENCE, 9 10.3389/fnins.2015.00148 APR 28 2015

Autophagy and Ubiquitination in Cardiovascular Diseases.

Martins-Marques T, Ribeiro-Rodrigues T, Pereira P, Codogno P, Girao H.

DNA Cell Biol. 2015 Jan 20

Bacterial Cellulose As a Support for the Growth of Retinal Pigment Epithelium

Goncalves, S; Padrao, J; Rodrigues, IP; Silva, JP; Sencadas, V; Lanceros-Mendez, S; Girao, H; Dourado, F; Rodrigues, LR

BIOMACROMOLECULES, 16 (4):1341-1351; 10.1021/acs.biomac.5b00129 APR 2015

Balancing the benefits and risks of low-dose glucocorticoid in rheumatoid arthritis

Santiago, T; Jacobs, JW; Saag, KG; Buttgereit, F; da Silva, JAP


Basic Scale on Insomnia complaints and Quality of Sleep (BaSIQS): Reliability, initial validity and normative scores in higher education students

Gomes, AA; Marques, DR; Meia-Via, AM; Meia-Via, M; Tavares, J; da Silva, CF; de Azevedo, MHP

Chronobiology International, 32 (3):428-440 10.3109/07420528.2014.986681 - APR 2015

Beyond Maastricht IV: are standard empiric triple therapies for Helicobacter pylori still useful in a South-European country?

Almeida N, Donato MM, Romãozinho JM, Luxo C, Cardoso O, Cipriano MA, Marinho C, Fernandes A, Calhau C, Sofia C.

BMC Gastroenterol. 2015 Feb 15;15(1):23

Bisphosphonate-related osteonecrosis of the jaw: specificities.

Paulo S, Abrantes AM, Laranjo M, Carvalho L, Serra A, Botelho MF, Ferreira MM.

Oncol Rev. 2014 Sep 23;8(2):254

Brain Activity during Lower-Limb Movement with Manual Facilitation: An fMRI Study.

de Almeida PM, Vieira AI, Canário NI, Castelo-Branco M, de Castro Caldas AL.

Neurol Res Int. 2015;2015:701452.

Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons

Curcio, M; Salazar, IL; Inacio, AR; Duarte, EP; Canzoniero, LMT; Duarte, CB

CELL DEATH & DISEASE, 6 10.1038/cddis.2014.578 FEB 2015

Bronchial-pulmonary adenocarcinoma subtyping relates with different molecular pathways.

Sousa V, Bastos B, Silva M, Alarcão AM, Carvalho L.

Rev Port Pneumol (2006). 2015 Mar 6.

Caffeine consumption and exacerbations of chronic obstructive pulmonary disease: Retrospective study.

Lopes PO, Alfaro TM, Lopes P, Cunha RA, Robalo Cordeiro C.

Rev Port Pneumol (2006). 2015 Jun 9.

Can Potassium Perchlorate and Sodium Iodine influence Iodine-131 uptake in Cholangiocarcinoma?

Brito, AF; Puga, T; Teixo, R; Fernandes, A; Brito, AF; Abrantes, AM;

Metello, LF; Tralhao, JG; Botelho, MF

European Journal of Nuclear Medicine and Molecular Imaging, 42 S295-S296; 1 Oct 2015

Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration?

Nunes AR, Alves MG, Moreira PI, Oliveira PF, Silva BM.

Curr Neuropharmacol. 2014 Dec;12(6):475-89.

Case Control Study of Rotavirus Vaccine Effectiveness in Portugal During 6 Years of Private Market Use

Marlow, R; Ferreira, M; Cordeiro, E; Trotter, C; Januario, L; Finn, A; Rodrigues, F


Cerebrospinal fluid Aβ40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease.

Baldeiras I, Santana I, Leitão MJ, Ribeiro MH, Pascoal R, Duro D, Lemos R, Santiago B, Almeida MR, Oliveira CR.

J Neurol Sci. 2015 Nov 15;358(1-2):308-16.

Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid oral delivery

Madureira, AR; Campos, DA; Fonte, P; Nunes, S; Reis, F; Gomes, AM; Sarmento, B; Pintado, MM

RSC ADVANCES, 5 (29):22665-22673; 10.1039/c4ra15802d 2015

Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers.

Leitão MJ, Baldeiras I, Herukka SK, Pikkarainen M, Leinonen V, Simonsen AH, Perret-Liaudet A, Fourier A, Quadrio I, Veiga PM, de Oliveira CR.

Front Neurol. 2015 Jul 8;6:153

Cholangiocarcinoma: from molecular biology to treatment.

Brito AF, Abrantes AM, Encarnação JC, Tralhão JG, Botelho MF.

Med Oncol. 2015 Nov;32(11):245.

Cholinergic stimulation with pyridostigmine protects myocardial infarcted rats against ischemic-induced arrhythmias and preserves connexin43 protein

Santos-Almeida, FM; Girao, H; da Silva, CAA; Salgado, HC; Fazan, R

American Journal of Physiology-Heart and Circulatory Physiology, 308 (2):H101-H107; 10.1152/ajpheart.00591.2014 JAN 15 2015

Circumferential vascular strain rate to estimate vascular load in aortic stenosis: a speckle tracking echocardiography study

Teixeira, R; Monteiro, R; Baptista, R; Barbosa, A; Leite, L; Ribeiro, M; Martins, R; Cardim, N; Goncalves, L


Clinical relevance of il-6 and tnf-alfa in the characterization of leukemic stem cells in MDS patients

Cortesao, E; Goncalves, AC; Geraldes, C; Pereira, A; Ribeiro, L; Costa, JMN; Ribeiro, ABS

Haematologica, 100 480-481; 1 JUN 2015

Comparative Effectiveness of Tocilizumab and TNF Inhibitors in Rheumatoid Arthritis Patients: Data from the Rheumatic Diseases Portuguese Register,

C Romão V, Santos MJ, Polido-Pereira J, Duarte C, Nero P, Miguel C, Costa JA, Bernardes M, Pimentel-Santos FM, Barcelos F, Costa L, Melo Gomes JA, Pereira da Silva JA, Branco JC, Canas da Silva J, Pereira da Silva JA, Fonseca JE, Canhão H.

Biomed Res Int. 2015;2015:279890.

Computer-aided diagnosis of Parkinson's disease based on [<sup>123</sup>I]FP-CIT SPECT binding potential images, using the voxels-as-features approach and support vector machines.

Oliveira FP, Castelo-Branco M.

J Neural Eng. 2015 Feb 24;12(2):026008

Conjugated linoleic acid improves oocyte cryosurvival through modulation of the cryoprotectants influx rate.

Matos JE, Marques CC, Moura TF, Baptista MC, Horta AE, Soveral G, Pereira RM.

Reprod Biol Endocrinol. 2015 Jun 12;13(1):60.

Connexin 43 ubiquitination determines the fate of gap junctions: restrict to survive.

Ribeiro-Rodrigues TM, Catarino S, Pinho MJ, Pereira P, Girao H.

Biochem Soc Trans. 2015 Jun 1;43(3):471-5.

Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases.

Madeira MH, Boia R, Santos PF, Ambrósio AF, Santiago AR.

Mediators Inflamm. 2015;2015:673090.

Convergence of finite difference schemes for nonlinear complex Reaction-diffusion processes

Araujo, A; Barbeiro, S; Serranho, P


Copper(I) complexes of methyl 4-aryl-6-methyl-3,4-dihydropyrimidine-2(1H)-thione-5-carboxylates. Synthesis, characterization and activity in human breast cancer cells

Gonzalez-Ballesteros, N; Perez-Alvarez, D; Henriques, MSC; Nascimento, BFO; Laranjo, M; Santos, K; Casalta-Lopes, J; Abrantes, AM; Botelho, MF; Pineiro, M; Paixao, JA; Rodriguez-Arguelles, MC

Inorganica Chimica Acta, 438 160-167; 10.1016/j.ica.2015.09.012 Nov 1

Cryopreservation of in vitro-produced sheep embryos: Effects of different protocols of lipid reduction.

Romão R, Marques CC, Baptista MC, Barbas JP, Horta AE, Carolino N, Bettencourt E, Pereira RM.

Theriogenology. 2015 Feb 28.

c-Src Function is Necessary and Sufficient for Triggering Microglial Cell Activation

Socodato, R; Portugal, CC; Domith, I; Oliveira, NA; Coreixas, VSM; Loiola, EC; Martins, T; Santiago, AR; Paes-de-Carvalho, R; Ambrosio, AF; Relvas, JB


63 (3):497-511; 10.1002/glia.22767 MAR 2015

Cutis Aplasia as a clinical hallmark for the syndrome associated with 19q13.11 deletion: the possible role for UBA2 gene.

Melo JB, Estevinho A, Saraiva J, Ramos L, Carreira IM.

Mol Cytogenet. 2015 Mar 26;8:21

Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat.

Sereno J, Vala H, Nunes S, Rocha-Pereira P, Carvalho E, Alves R, Teixeira F, Reis F.

J Physiol Pharmacol. 2015 Apr;66(2):285-99.

Daily consumption of white tea (Camellia sinensis (L.)) improves the cerebral cortex metabolic and oxidative profile in prediabetic Wistar rats

Nunes, AR; Alves, MG; Tomas, GD; Conde, VR; Cristovao, AC; Moreira, PI;

Oliveira, PF; Silva, BM

British Journal of Nutrition, 113 (5):832-842; 10.1017/S0007114514004395

MAR 14 2015

DAS28, CDAI and SDAI cut-offs do not translate the same information: results from the Rheumatic Diseases Portuguese Register

Martins FM, da Silva JA, Santos MJ, Vieira-Sousa E, Duarte C, Santos H, Costa JA, Pimentel-Santos FM, Cunha I, Cunha Miranda L, Nóvoa T, Cruz M, Bernardes M, Araujo D, Pereira Silva JA, Silva JC, Branco JC, Gomes JA, Faustino A, Fonseca JE, Canhão H.

Rheumatology (Oxford). 2015 Feb;54(2):286-91.

Dehydroepiandrosterone and 7-oxo-dehydroepiandrosterone in male reproductive health: implications of differential regulation of human Sertoli cells metabolic profile.

Dias TR, Alves MG, Almeida SP, Silva J, Barros A, Sousa M, Silva BM, Silvestre SM, Oliveira PF.

J Steroid Biochem Mol Biol. 2015 Jun 29

Denture impaction in the thoracic esophagus: surgical treatment - a case report

Alexandrino H, Fernandes M, Ferreira L, Tralhão JG, Castro E Sousa F.

Rev Port Cir Cardiotorac Vasc. 2012 Jan-Mar;19(1):27-9.

Design, synthesis and bioevaluation of tacrine hybrids with cinnamate and cinnamylidene acetate derivatives as potential anti-Alzheimer drugs

Quintanova, C; Keri, RS; Marques, SM; G-Fernandes, M; Cardoso, SM; Serralheiro, ML; Santos, MA

MedChemComm, 6 (11):1969-1977; 10.1039/c5md00236b 2015

Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity.

Bento D, Staats HF, Gonçalves T, Borges O.

Eur J Pharm Biopharm. 2015 Mar 26.

Diabetic hyperglycemia reduces Ca2+ permeability of extrasynaptic AMPA receptors in AII amacrine cells.

Castilho Á, Madsen E, Ambrósio AF, Veruki ML, Hartveit E.

J Neurophysiol. 2015 Sep;114(3):1545-53.

Differences and similarities in rheumatology specialty training programmes across European countries.

Sivera F, Ramiro S, Cikes N, Dougados M, Gossec L, Kvien TK, Lundberg IE, Mandl P, Moorthy A, Panchal S, da Silva JA, Bijlsma JW; on behalf of the Working Group on Training in Rheumatology across Europe.

Ann Rheum Dis. 2015 Mar 6.

Differential Role of the Proteasome in the Early and Late Phases of BDNF-Induced Facilitation of LTP.

Santos AR, Mele M, Vaz SH, Kellermayer B, Grimaldi M, Colino-Oliveira M, Rombo DM, Comprido D, Sebastião AM, Duarte CB.

J Neurosci. 2015 Feb 25;35(8):3319-29.

Direct production of 99mTc-Technetium using low energy cyclotrons and radionuclidic purity: our results so far using natMo-Molybdenum

Metello, L; Costa, P; Cunha, L; Jonhson, R; Matei, L; Gelbart, W; Obermair, J; Artner, C; Lass, P; Currie, G; Craciun, L; Niculae, D; Carmo, S; Alves, F; Botello, M

European Journal of Nuclear Medicine and Molecular Imaging, 42 S197-S198; 1 OCT 2015

Disruption of a neural microcircuit in the rod pathway of the mammalian retina by diabetes mellitus.

Castilho Á, Ambrósio AF, Hartveit E, Veruki ML.

J Neurosci. 2015 Apr 1;35(13):5422-33.

Dissecting the role of microRNAs and their therapeutic potential in Alzheimer's disease

Viegas, AT; Carmona, V; de Almeida, LP; de Magalhaes, JP; Cardoso, AL

Viegas, A. T.; Carmona, V.; Pereira de Almeida, L.; de Magalhaes, J. P.; Cardoso, A. L.

FEBS JOURNAL, 282 217-217; 1 SI JUL 2015

Distinct parameters of the basophil activation test reflect the severity and threshold of allergic reactions to peanut.

Santos AF, Du Toit G, Douiri A, Radulovic S, Stephens A, Turcanu V, Lack G.

J Allergy Clin Immunol. 2015 Jan;135(1):179-86.

Does the percutaneous left atrium appendage closure influence left atrial performance?

Madeira, M; Teixeira, R; Faustino, C; Paiva, L; Reis, L; Almeida, I; Quaresma, A; Botelho, A; Costa, M; Lino, G

European Heart Journal, 36 20-21; 1 AUG 1 2015

Double-balloon enteroscopy in the management of patients with Peutz-Jeghers syndrome: A retrospective cohort multicenter study

Serrano, M; Mao-de-Ferro, S; Pinho, R; Marcos-Pinto, R; Figueiredo, P; Ferreira, S; Claro, I; Mascarenhas-Saraiva, M; Dias-Pereira, A


Drug transporters play a key role in the complex process of Imatinib resistance in vitro.

Alves R, Fonseca AR, Gonçalves AC, Ferreira-Teixeira M, Lima J, Abrantes AM, Alves V, Rodrigues-Santos P, Jorge L, Matoso E, Carreira IM, Botelho MF, Sarmento-Ribeiro AB.

Leuk Res. 2015 Mar;39(3):355-60.

Dual functionality of phosphonic-acid-appended phthalocyanines: inhibitors of urokinase plasminogen activator and anticancer photodynamic agents.

Venkatramaiah N, Pereira PM, Almeida Paz FA, Ribeiro CA, Fernandes R, Tomé JP.

Chem Commun (Camb). 2015 Nov 4;51(85):15550-3

DVL1 frameshift mutations clustering in the penultimate exon cause autosomal-dominant Robinow syndrome.

Saraiva JM, Hove H, Skovby F, Kayserili H, Estrella E, Vulto-van Silfhout AT, Steehouwer M, Muzny DM, Sutton VR, Gibbs RA; Carvalho CM; et al.

Am J Hum Genet. 2015 Apr 2;96(4):612-22.

Dynamic expansion and functional tuning of natural killer cells in chronic Myeloid Leukemia

Santos, PR; Couceiro, P; Almeida, J; Queiros, D; Gomes-Silva, D; Alves, V; Ruzickova, L; Freitas-Tavares, P; Santos-Rosa, M

Haematologica, 100 60-60; 1 JUN 2015

Early disrupted neurovascular coupling and changed event level hemodynamic response function in type 2 diabetes: an fMRI study.

Duarte JV, Pereira JM, Quendera B, Raimundo M, Moreno C, Gomes L, Carrilho F, Castelo-Branco M.

J Cereb Blood Flow Metab. 2015 Jun 10

Effect of intentional abutment disconnection on the micro-movements of the implant-abutment assembly: a 3D digital image correlation analysis.

Messias A, Rocha S, Calha N, Neto MA, Nicolau P, Guerra F.

Clin Oral Implants Res. 2015 May 6

Effects of drugs of abuse on the central neuropeptide Y system

Gonçalves J, Martins J, Baptista S, Ambrósio F, Silva AP

Addiction Biology, 2015 (in press)

Effects of emotional valence and three-dimensionality of visual stimuli on brain activation: an fMRI study.

Dores AR, Almeida I, Barbosa F, Castelo-Branco M, Monteiro L, Reis M, de Sousa L, Caldas AC.

NeuroRehabilitation. 2013;33(4):505-12.

Embriões Excedentários: entre a Técnica, a Lei e a Ética

Silvestre, Margarida

Colecção do Centro de Direito Biomédico, nº 23.

Coimbra, Coimbra Editora, 2015.

Emergent biomarkers of residual cardiovascular risk in patients with low HDL-c and/or high triglycerides and average LDL-c concentrations: focus on HDL subpopulations, Oxidized LDL, adiponectin, and uric acid.

Mascarenhas-Melo F, Palavra F, Marado D, Sereno J, Teixeira-Lemos E, Freitas I, Isabel-Mendonça M, Pinto R, Teixeira F, Reis F.

ScientificWorldJournal. 2013 Nov 4;2013:387849

Endothelial progenitor cells in diabetic patients with myocardial infarction - can statins improve their function?

António N, Soares A, Fernandes R, Soares F, Lopes A, Carvalheiro T, Paiva A, Providência LA, Gonçalves L, Fontes Ribeiro C.

Eur J Pharmacol. 2014 Oct 15;741:25-36.

Enhanced Amyloidogenic Processing of Amyloid Precursor Protein and Cell Death Under Prolonged Endoplasmic Reticulum Stress in Brain Endothelial Cells

Placido, AI; Oliveira, CR; Moreira, PI; Pereira, CMF

Molecular Neurobiology, 51 (2):571-590; 10.1007/s12035-014-8819-1 APR 2015

Evaluation of Radioiodine Therapy with an Adapted Dosimetric Approach in Patients with Hyperthyroidism

Fernandes, A; Faria, T; Coelho, P; Casalta-Lopes, J; Oliveira, A; Alves, V; Pinto, A; Perez, M; Vieira, T; Pereira, J

European Journal of Nuclear Medicine and Molecular Imaging, 42 S768-S769; 1 OCT 2015

Evaluation of snps on the toll-like receptors, nod-like receptors and cd14 gene in the recognition and in autophagic modulation in response to infection by mycobacterium leprae

Mazini, PS; Rodrigues-Santos, P; Santos-Rosa, M; Vicentin, HA; Shinzato, AH; Shinzato, MH; Sell, AM; Visentainer, JEL

Human Immunology, 76 83-83; 1 2015

Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis

Rufino, AT; Ribeiro, M; Sousa, C; Judas, F; Salgueiro, L; Cavaleiro, C; Mendes, AF

European Journal of Pharmacology, 750 141-150; 10.1016/j.ejphar.2015.01.018 MAR 5 2015

Exercise alters liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitis.

Gonçalves IO, Maciel E, Passos E, Torrella JR, Rizo D, Viscor G, Rocha-Rodrigues S, Santos-Alves E, Domingues MR, Oliveira PJ, Ascensão A, Magalhães J.

Int J Biochem Cell Biol. 2014 Sep;54:163-73.

Exposure to ros induces dna damage and influences dna methylation in normal and malignant hematological cell lines

Goncalves, AC; Alves, R; Pires, A; Jorge, J; Mota-Vieira, L; Nascimento-Costa, JM; Sarmento-Ribeiro, AB

Haematologica, 100 366-366; 1 JUN 2015

Fiability Study of Diabetes Empowerment Scale: Short Version

Aveiro M, Santiago LM, Lopes Ferreira P, Simões JA.

Acta Med Port. 2015 Mar-Apr;28(2):177-81.

Five-year review of an international clinical research-training program.

Suemoto CK, Ismail S, Corrêa PC, Khawaja F, Jerves T, Pesantez L, Germani AC, Zaina F, Dos Santos AC Junior, de Oliveira Ferreira RJ, Singh P, Paulo JV, Matsubayashi SR, Vidor LP, Andretta G, Tomás R, Illigens BM, Fregni F.

Adv Med Educ Pract. 2015 Apr 1;6:249-257

Functional hepatocellular regeneration in elderly patients undergoing hepatectomy

Fernandes, AI; Tralhao, JG; Abrantes, A; Hoti, E; Alexandrino, H; Oliveiros, B; Ferreira, M; Botelho, MF; Sousa, FC

LIVER INTERNATIONAL, 35 (4):1116-1123; 10.1111/liv.12433 APR 2015

Gamma-hydroxybutyric acid endogenous production and post-mortem behaviour - the importance of different biological matrices, cut-off reference values, sample collection and storage conditions.

Castro AL, Dias M, Reis F, Teixeira HM.

J Forensic Leg Med. 2014 Oct;27:17-24

Gastroprotective effect of Cymbopogon citratus infusion on acute ethanol-induced gastric lesions in rats.

Sagradas J, Costa G, Figueirinha A, Castel-Branco MM, Silvério Cabrita AM, Figueiredo IV, Batista MT.

J Ethnopharmacol. 2015 Sep 15; 173:134-8.

Gender mismatch between donor and recipient is a factor of morbidity but does not condition survival after cardiac transplantation.

Correia P, Prieto D, Batista M, Antunes MJ.

Transpl Int. 2014 Dec;27(12):1303-10.

Genetic polymorphisms of phase I and phase II metabolic enzymes as modulators of lung cancer susceptibility

Mota, P; Silva, HC; Soares, MJ; Pego, A; Loureiro, M; Cordeiro, CR; Regateiro, FJ

Mota, P.; Silva, H. C.; Soares, M. J.; Pego, A.; Loureiro, M.; Robalo Cordeiro, C.; Regateiro, F. J.


Genetic polymorphisms of phase I and phase II metabolic enzymes as modulators of lung cancer susceptibility.

Mota P, Silva HC, Soares MJ, Pego A, Loureiro M, Cordeiro CR, Regateiro FJ.

J Cancer Res Clin Oncol. 2015 May;141(5):851-60.

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study.

Cuyvers E, van der Zee J, Bettens K, Engelborghs S, Vandenbulcke M, Robberecht C, Dillen L, Merlin C, Geerts N, Graff C, Thonberg H, Chiang HH, Pastor P, Ortega-Cubero S, Pastor MA, Nacmias B, Sorbi S, Sanchez-Valle R, Lladó A, Gelpi E, Almeida MR, Santana I, et al.

Neurobiol Aging. 2015 Feb 19 - 00114-1.

Genetic Variation of MT-ND Genes in Frontotemporal Lobar Degeneration: Biochemical Phenotype-Genotype Correlation

Gaspar, R; Santana, I; Mendes, C; Fernandes, AS; Duro, D; Simoes, M; Luis, D; Santos, MJ; Grazina, M

NEURODEGENERATIVE DISEASES, 15 (2):70-80; 10.1159/000380766 2015

Genetically induced impairment of retinal ganglion cells at the axonal level is linked to extrastriate cortical plasticity.

Mateus C, d'Almeida OC, Reis A, Silva E, Castelo-Branco M.

Brain Struct Funct. 2015 Feb 14.

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.

Léveillé N, Melo CA, Rooijers K, Díaz-Lagares A, Melo SA, Korkmaz G, Lopes R, Akbari Moqadam F, Maia AR, Wijchers PJ, Geeven G, den Boer ML, Kalluri R, de Laat W, Esteller M, Agami R.

Nat Commun. 2015 Mar 27;6:6520.

Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide.

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Hematogenic Dissemination of Triple-negative Versus Hormonal Receptor-positive Breast Cancer Cells.

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PHARMACOGENOMICS JOURNAL, 15 (3):288-292; 10.1038/tpj.2014.67 JUN 2015

High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia.

Othman MA, Melo JB, Carreira IM, Rincic M, Glaser A, Grygalewicz B, Gruhn B, Wilhelm K, Rittscher K, Meyer B, Silva ML, de Jesus Marques Salles T, Liehr T.

Mol Cytogenet. 2015 Jun 30;8:45.

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International Journal of Dental Hygiene, 13 (2):138-144;

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Horizontal Resorption of Fresh-Frozen Corticocancellous Bone Blocks in the Reconstruction of the Atrophic Maxilla at 5 Months.

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Identification of endogenous metabolites in human sperm cells using <sup>1</sup> H-NMR and GC-MS.

Paiva C, Amaral A, Rodriguez M, Canyellas N, Correig X, Ballescà JL, Ramalho-Santos J, Oliva R.

Andrology. 2015 Apr 8.

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Ruzickova, L; Tavares, PF; Santos, PR; Couceiro, P; Ribeiro, L

Haematologica, 100 444-444; 1 JUN 2015

Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder.

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Haematologica, 100 688-689; 1 JUN 2015

Impact of nf-kb expression in the prognosis of multiple myeloma patients treated with bortezomib in frontline regimens

Geraldes, C; Goncalves, AC; Alves, R; Cortesao, E; Ribeiro, L; Costa, JMN; Sarmento-Ribeiro, AB

Haematologica, 100 514-515; 1 JUN 2015

Impact of prior chronic statin therapy and high-intensity statin therapy at discharge on circulating endothelial progenitor cell levels in patients with acute myocardial infarction: a prospective observational study.

António N, Fernandes R, Soares A, Soares F, Lopes A, Carvalheiro T, Paiva A, Pêgo GM, Providência LA, Gonçalves L, Ribeiro CF.

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Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress.

Santana MM, Rosmaninho-Salgado J, Cortez V, Pereira FC, Kaster MP, Aveleira CA, Ferreira M, Álvaro AR, Cavadas C.

Eur Neuropsychopharmacol. 2015 Oct;25(10):1753-66.

Implementation of evidence-based dentistry into practice: analysis of awareness, perceptions and attitudes of dentists in the World Dental Federation–European Regional Organization zone through a multicentre questionnaire

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International Dental Journal, 2015 (in press)

Inactivation of adenosine A<sub>2A</sub> receptors reverses working memory deficits at early stages of Huntington's disease models.

Li W, Silva HB, Real J, Wang YM, Rial D, Li P, Payen MP, Zhou Y, Muller CE, Tomé AR, Cunha RA, Chen JF.

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Inferior frontal gyrus white matter abnormalities in obsessive-compulsive disorder.

Gonçalves ÓF, Sousa S, Maia L, Carvalho S, Leite J, Ganho A, Fernandes-Gonçalves A, Frank B, Pocinho F, Carracedo A, Sampaio A.

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Influence of ABC transporters' genetic profiles in the development of monoclonal gammopathies

Fernandes, SI; Gonalves, AC; Jorge, J; Geraldes, C; Alves, R; Pires, A; Veiga, S; Cortesao, E; Ribeiro, L; Ribeiro, ABS

Haematologica, 100 498-498; 1 JUN 2015

Insulin Resistance, Dyslipidemia and Cardiovascular Changes in a Group of Obese Children.

Pires A, Martins P, Pereira AM, Silva PV, Marinho J, Marques M, Castela E, Sena C, Seiça R.

Arq Bras Cardiol. 2015 Jan 23

Intensive Monitoring of Adverse Drug Reactions-State of the Art

Joaquim, JJ; Harmark, L; Ribeiro, CF; Mateos-Campos, R

DRUG SAFETY, 38 (10):992-992; OCT 2015

Irisin and Myonectin Regulation in the Insulin Resistant Muscle: Implications to Adipose Tissue: Muscle Crosstalk

Gamas, L; Matafome, P; Seicaa, R

JOURNAL OF DIABETES RESEARCH, 10.1155/2015/359159 2015

Irisin and Myonectin Regulation in the Insulin Resistant Muscle: Implications to Adipose Tissue: Muscle Crosstalk.

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Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.

Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F.

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Iron-Hepcidin Dysmetabolism, Anemia and Renal Hypoxia, Inflammation and Fibrosis in the Remnant Kidney Rat Model

Garrido, P; Ribeiro, S; Fernandes, J; Vala, H; Bronze-Da-Rocha, E; Rocha-Pereira, P; Belo, L; Costa, E; Santos-Silva, A; Reis, F

PLOS ONE, 10 (4):10.1371/journal.pone.0124048 APR 13 2015

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

Martins-Marques, T; Catarino, S; Zuzarte, M; Marques, C; Matafome, P; Pereira, P; Girao, H

Biochemical Journal, 467 231-245; 10.1042/BJ20141370 2 APR 15 2015

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes.

Martins-Marques T, Catarino S, Zuzarte M, Marques C, Matafome P, Pereira P, Girão H.

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K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy

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SCIENTIFIC REPORTS, 5 10.1038/srep10210 MAY 11 2015

Left atrial dysfunction in type 2 diabetes mellitus: insights from cardiac MRI.

Graça B, Ferreira MJ, Donato P, Gomes L, Castelo-Branco M, Caseiro-Alves F.

Eur Radiol. 2014 Nov;24(11):2669-76

Leptin and resistin in overweight patients with and without asthma.

Muc M, Todo-Bom A, Mota-Pinto A, Vale-Pereira S, Loureiro C.

Allergol Immunopathol (Madr). 2014 Sep-Oct;42(5):415-21

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease.

Esteves S, Duarte-Silva S, Naia L, Neves-Carvalho A, Teixeira-Castro A, Rego AC, Silva-Fernandes A, Maciel P.

PLoS One. 2015 Oct 27;10(10):e0141610

Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells.

Perfeito R, Lázaro DF, Outeiro TF, Rego AC.

Mol Cell Neurosci. 2014 Sep;62:51-9

Liver iron regulates hepcidin expression. Studies in a rat model of chronic renal failure under recombinant human erythropoietin therapy

Ribeiro, S; Garrido, P; Fernandes, J; Rocha, S; Nunes, S; Rocha-Pereira, P; Costa, E; Belo, L; Reis, F; Santos-Silva, A

FEBS JOURNAL, 282 98-98; 1 SI JUL 2015

Localization and Trafficking of Amyloid-beta Protein Precursor and Secretases: Impact on Alzheimer's Disease

Agostinho, P; Pliassova, A; Oliveira, CR; Cunha, RA

JOURNAL OF ALZHEIMERS DISEASE, 45 (2):329-347; 10.3233/JAD-142730 2015

Long-term exposure to high glucose increases the content of several exocytotic proteins and of vesicular GABA transporter in cultured retinal neural cells.

Baptista FI, Castilho ÁF, Gaspar JM, Liberal JT, Aveleira CA, Ambrósio AF.

Neurosci Lett. 2015 Jun 30. pii: S0304-3940(15)30001-X

Long-term globular adiponectin administration improves adipose tissue dysmetabolism in high-fat diet-fed Wistar rats.

Matafome P, Rodrigues T, Pereira A, Letra L, Azevedo H, Paixão A, Silvério M, Almeida A, Sena C, Seiça R.

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Lowering pulmonary wedge pressure after heart transplant: pulmonary compliance and resistance effect.

Moreira N, Baptista R, Costa S, Franco F, Pêgo M, Antunes M.

Arq Bras Cardiol. 2015 Sep;105(3):292-300

Low-level laser therapy on skeletal muscle inflammation: evaluation of irradiation parameters.

Mantineo M, Pinheiro JP, Morgado AM.

J Biomed Opt. 2014 Sep;19(9):98002.

Lung adenocarcinoma: Sustained subtyping with immunohistochemistry and EGFR, HER2 and KRAS mutational status.

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Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.

Kostic I, Fidalgo-Carvalho I, Aday S, Vazão H, Carvalheiro T, Grãos M, Duarte A, Cardoso C, Gonçalves L, Carvalho L, Paiva A, Ferreira L.

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Macrophage Mitochondrial and Stress Response to Ingestion of Cryptococcus neoformans

Coelho, C; Souza, ACO; Derengowski, LD; de Leon-Rodriguez, C; Wang, B;

Leon-Rivera, R; Bocca, AL; Goncalves, T; Casadevall, A

JOURNAL OF IMMUNOLOGY, 194 (5):2345-2357; MAR 1 2015

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation.

Bousquet J, Schunemann HJ, Fonseca J, Postma D, Potter P, Price D, Rabe KF, Raciborski F, Radier Pontal F, Repka-Ramirez S, Robalo-Cordeiro C, et al.

Allergy. 2015 Nov;70(11):1372-92.

Medico-legal litigation in Obstetrics: a characterization analysis of a decade in Portugal.

Domingues AP, Belo A, Moura P, Vieira DN.

Rev Bras Ginecol Obstet. 2015 May;37(5):241-6

Membrane progesterone receptors in human regulatory T cells: a reality in pregnancy.

Areia A, Vale-Pereira S, Alves V, Rodrigues-Santos P, Moura P, Mota-Pinto A.

BJOG. 2015 Feb 2.

Metabolic control and therapeutic profile of patients with diabetes in Portuguese primary care (TEDDI CP)

Cardoso, SM; Rodrigues, E; Valadas, C; Fonseca, C

PRIMARY CARE DIABETES, 9 (3):172-178; 10.1016/j.pcd.2014.06.004 JUN 2015

Metabolic fingerprints in testicular biopsies from type 1 diabetic patients.

Alves MG, Martins AD, Moreira PI, Carvalho RA, Sousa M, Barros A, Silva J, Pinto S, Simões T, Oliveira PF.

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Methamphetamine decreases dentate gyrus stem cell self-renewal and shifts the differentiation towards neuronal fate.

Baptista S, Lasgi C, Benstaali C, Milhazes N, Borges F, Fontes-Ribeiro C, Agasse F, Silva AP.

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Microfluidic assisted one-step fabrication of porous silicon@acetalated dextran nanocomposites for precisely controlled combination chemotherapy.

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MicroRNAs in Glioblastoma: Role in Pathogenesis and Opportunities for Targeted Therapies

Costa, PM; Cardoso, AL; Mano, M; de Lima, MCP

Cns & Neurological Disorders-Drug Targets, 14 (2):222-238; 2015

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined

With sunitinib: A new multimodal gene therapy approach for glioblastoma

Costa, PM; Cardoso, AL; Custodia, C; Cunha, P; de Almeida, LP; de

Lima, MCP


Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells.

Vega-Naredo I, Loureiro R, Mesquita KA, Barbosa IA, Tavares LC, Branco AF, Erickson JR, Holy J, Perkins EL, Carvalho RA, Oliveira PJ.

Cell Death Differ. 2014 Oct;21(10):1560-74.

Mitral valve surgery after percutaneous mitral commissurotomy: is repair still feasible?

Coutinho GF, Branco CF, Jorge E, Correia PM, Antunes MJ.

Eur J Cardiothorac Surg. 2015 Jan;47(1):e1-6

MLLT10 and IL3 rearrangement together with a complex four-way translocation and trisomy 4 in a patient with early T-cell precursor acute lymphoblastic leukemia: A case report.

Othman MA, Melo JB, Carreira IM, Rincic M, Alhourani E, Wilhelm K, Gruhn B, Glaser A, Liehr T.

Oncol Rep. 2015 Feb;33(2):625-30

Modeling chronic brain exposure to amphetamines using primary rat neuronal cortical cultures.

Nogueira TB, da Costa Araújo S, Carvalho F, Pereira FC, Fernandes E, Bastos ML, Costa VM, Capela JP.

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Modulation of endoplasmic reticulum stress: an opportunity to prevent neurodegeneration?

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Molecular identification and genotyping of Pseudomonas aeruginosa isolated from cystic fibrosis and non-cystic fibrosis patients with bronchiectasis.

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Pathog Dis. 2015 Mar;73(2):1-7

Morphologic and Molecular Features of Hepatocellular Adenoma with Gadoxetic Acid-enhanced MR Imaging.

Ba-Ssalamah A, Antunes C, Feier D, Bastati N, Hodge JC, Stift J, Cipriano MA, Wrba F, Trauner M, Herold CJ, Caseiro-Alves F.

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Multidrug and Extensive Drug Resistance in Pseudomonas aeruginosa Clinical

Isolates from a Portuguese Central Hospital: 10-Year Survey

Pereira, SG; Marques, M; Pereira, J; Cardoso, O

MICROBIAL DRUG RESISTANCE, 21 (2):194-200; 10.1089/mdr.2014.0137 APR 1 2015

Necromechanics: Death-induced changes in the mechanical properties of human tissues.

Martins PA, Ferreira F, Natal Jorge R, Parente M, Santos A.

Proc Inst Mech Eng H. 2015 May;229(5):343-9.

Negative impact of atrial fibrillation and pulmonary hypertension after mitral valve surgery in asymptomatic patients with severe mitral regurgitation: a 20-year follow-up.

Coutinho GF, Garcia AL, Correia PM, Branco C, Antunes MJ.

Eur J Cardiothorac Surg. 2015 Oct;48(4):548-55; discussion 555-6

Neighbourhood socioeconomic disadvantage and fruit and vegetable consumption: a seven countries comparison.

Ball K, Lamb KE, Costa C, Cutumisu N, Ellaway A, Kamphuis CB, Mentz G, Pearce J, Santana P, Santos R, Schulz AJ, Spence JC, Thornton LE, van Lenthe FJ, Zenk SN.

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Neural signals evoked by stimuli of increasing social scene complexity are detectable at the single-trial level and right lateralized.

Amaral CP, Simões MA, Castelo-Branco MS.

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Neuro-Ophthalmic Syndromes and Processing Speed in Multiple Sclerosis.

Costa SL, Gonçalves ÓF, Chiaravalloti ND, DeLuca J, Almeida J.

J Neuroophthalmol. 2015 Jun 30

Neuropeptide Y system in the retina: From localization to function.

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Neurotrophic keratopathy: a new therapeutic approach using a novel matrix regenerating agent

Gil, JMBCQ; Guerra, MG; Costa, E; Rosa, A; Quadrado, MJ; Murta, JN

Investigative Ophthalmology & Visual Science, 56 (7):JUN 2015

New estradiol based In-111 complex towards the estrogen receptor

Vultos, F; Cunha, S; Fernandes, C; Oliveira, MC; Marques, F; Botelho, MF; Santos, I; Gano, L

Radiochimica Acta, 103 (11):765-776; 10.1515/ract-2014-2355 Nov 2015

NMR metabolomics of human lung tumours reveals distinct metabolic signatures for adenocarcinoma and squamous cell carcinoma.

Rocha CM, Barros AS, Goodfellow BJ, Carreira IM, Gomes A, Sousa V, Bernardo J, Carvalho L, Gil AM, Duarte IF.

Carcinogenesis. 2015 Jan;36(1):68-75.

Normalized uptake fraction: a new approach for image quantification

Alves, P; Silva, AF; Botelho, MF

European Journal of Nuclear Medicine and Molecular Imaging, 42 S393-S394; 1 OCT 2015

Nosewitness identification: effects of negative emotion.

Alho L, Soares SC, Ferreira J, Rocha M, Silva CF, Olsson MJ.

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Nosewitness identification: lineup test performance following emotion (crime) and neutral videos

Alho, L; Soares, SC; Ferreira, J; Rocha, M; Valente, D; Silva, CF; Olsson, MJ

Chemical Senses, 40 (3):264-264; MAR 2015

Novel 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine fused chlorins as very active photodynamic agents for melanoma cells.

Pereira NA, Laranjo M, Pineiro M, Serra AC, Santos K, Teixo R, Abrantes AM, Gonçalves AC, Sarmento Ribeiro AB, Casalta-Lopes J, Botelho MF, Pinho e Melo TM.

Eur J Med Chem. 2015 Oct 20;103:374-80

Novel Cryptic Rearrangements in Adult B-Cell Precursor Acute Lymphoblastic Leukemia Involving the MLL Gene.

Othman MA, Grygalewicz B, Pienkowska-Grela B, Rincic M, Rittscher K, Melo JB, Carreira IM, Meyer B, Marzena W, Liehr T.

J Histochem Cytochem. 2015 May;63(5):384-90

Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination.

Fonseca NA, Rodrigues AS, Rodrigues-Santos P, Alves V, Gregório AC, Valério-Fernandes Â, Gomes-da-Silva LC, Rosa MS, Moura V, Ramalho-Santos J, Simões S, Moreira JN.

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Nutritional and lifestyle risk factors in AMD. The Coimbra Eye Study

Farinha, CL; Mira, F; Santos, L; Nunes, S; Pedroso, A; Lains, I; Cachulo, ML; Silva, R

Investigative Ophthalmology & visual science, 56 (7): Jun 2015

Obesity: Paradigm of Endothelial Dysfunction in Paediatric Age Groups

Pires A, Castela E, Sena C, Seiça R.

Acta Med Port. 2015 Mar-Apr;28(2):233-239

Ocular Manifestations and Therapeutic Options in Patients with Familial Amyloid Polyneuropathy: A Systematic Review.

Martins AC, Rosa AM, Costa E, Tavares C, Quadrado MJ, Murta JN.

Biomed Res Int. 2015;2015:282405

Operational Definition of Active and Healthy Ageing (AHA): A Conceptual Framework.

Bousquet J, Robalo-Cordeiro C, Romano V, Roubille F, Schulz H, Scott A, Senesse P, Slagter S, Smit HA, Somekh D, Stafford M, Suanzes J, Todo-Bom A, et al.

J Nutr Health Aging. 2015 Nov;19(9):955-60.

Operational definition of active and healthy ageing (AHA): The European Innovation Partnership (EIP) on AHA Reference Site questionnaire

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J Am Med Dir Assoc. 2015 Dec 1;16(12):1020-1026

Optogenetic activation of intracellular adenosine A<sub>2A</sub> receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory.

Li P, Rial D, Canas PM, Yoo JH, Li W, Zhou X, Wang Y, van Westen GJ, Payen MP, Augusto E, Gonçalves N, Tomé AR, Li Z, Wu Z, Hou X, Zhou Y, PIJzerman A, Boyden ES, Cunha RA, Qu J, Chen JF.

Mol Psychiatry. 2015 Feb 17

Oropharyngeal Carriage of Meningococcus in Portugal by Group and Clonal Complex 6 Years After Adolescent Vaccine Campaign.

Rodrigues F, Morales-Aza B, Christensen H, Giles J, Ferreira M, Sikora P, Madanelo I, Lucidarme J, Januário L, Finn A.

Pediatr Infect Dis J. 2015 Nov;34(11):1267-9

Oscillations or Synchrony? Disruption of Neural Synchrony despite Enhanced Gamma Oscillations in a Model of Disrupted Perceptual Coherence

Castelhano, J; Bernardino, I; Rebola, J; Rodriguez, E; Castelo-Branco, M

Journal of Cognitive Neuroscience, 27 (12):2416-2426; Dec 2015

Outcome after heart transplantation from older donor age: expanding the donor pool

Prieto, D; Correia, P; Baptista, M; Antunes, MJ

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 47 (4):672-678; 10.1093/ejcts/ezu257 APR 2015

Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease.

Silva A, Naia L, Dominguez A, Ribeiro M, Rodrigues J, Vieira OV, Lessmann V, Rego AC.

Neurodegener Dis. 2015 Apr 21.

Oxaliplatin toxicity presenting as a liver nodule - case report

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BMC CANCER, 15 10.1186/s12885-015-1247-4 APR 10 2015

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.

Mota SI, Costa RO, Ferreira IL, Santana I, Caldeira GL, Padovano C, Fonseca AC, Baldeiras I, Cunha C, Letra L, Oliveira CR, Pereira CM, Rego AC.

Biochim Biophys Acta. 2015 Apr 6;1852(7):1428-1441

Oxidative stress levels are correlated with P15 and P16 gene promoter methylation in myelodysplastic syndrome patients.

Gonçalves AC, Cortesão E, Oliveiros B, Alves V, Espadana AI, Rito L, Magalhães E, Pereira S, Pereira A, Costa JM, Mota-Vieira L, Sarmento-Ribeiro AB.

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OXPHOS dysfunction regulates integrin-beta 1 modifications and enhances cell motility and migration

Nunes, JB; Peixoto, J; Soares, P; Maximo, V; Carvalho, S; Pinho, SS; Vieira, AF; Paredes, J; Rego, AC; Ferreira, IL; Gomez-Lazaro, M; Sobrinho-Simoes, M; Singh, KK; Lima, J HUMAN MOLECULAR GENETICS, 24 (7):1977-1990; 10.1093/hmg/ddu612 APR 2015

Patients' views on the embryo storage time limits.

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Percutaneous aortic and mitral valve implantation. Is it ready to match the results of contemporary surgical valve replacement?

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Perfectionism and disordered eating in overweight woman.

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Performance indicators evaluation of the population-based breast cancer screening programme in Northern Portugal using the European Guidelines.

Bento MJ, Gonçalves G, Aguiar A, Castro C, Veloso V, Rodrigues V.

Cancer Epidemiol. 2015 Oct;39(5):783-9.

Periodic alternating nystagmus. A case report.

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Acta Otorrinolaringol Esp. 2015 Apr 9

Perioperative morbidity and mortality in the first year of life: a systematic review (1997-2012).

Catré D, Lopes MF, Viana JS, Cabrita AS.

Braz J Anesthesiol. 2015 Sep-Oct;65(5):384-94.

Pharmacovigilance in Portugal: Activity of the Central Pharmacovigilance Unit

Batel-Marques F, Mendes D, Alves C, Penedones A, Dias P, Martins A, Santiago LM, Fontes-Ribeiro C, Caramona M, Macedo T.

Acta Med Port. 2015 Mar-Apr;28(2):222-32.

Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers.

Marques-Aleixo I, Santos-Alves E, Balça MM, Rizo-Roca D, Moreira PI, Oliveira PJ, Magalhães J, Ascensão A.

Neuroscience. 2015 Jun 24;301:480-495.

Pilot study on the European Portuguese version of the Confusion Assessment Method.

Martins S, Moldes P, Pinto-de-Sousa J, Conceição F, Paiva JA, Simões MR, Fernandes L.

Acta Neuropsychiatr. 2014 Oct;26(5):321-4.

Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis, not for hepatocellular carcinoma screening.

Simão A, Madaleno J, Silva N, Rodrigues F, Caseiro P, Costa JN, Carvalho A.

BMC Gastroenterol. 2015 Jun 30;15(1):73.

Police shootings against civilians in Portugal: Contextual, forensic medical and judicial characterization.

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Polymorphisms of dnmts and folate/methionine metabolism genes influence DNA methylation, genetic susceptibility and prognosis of myeloid neoplasia patients

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Haematologica, 100 236-236; 1 JUN 2015

Porto-pulmonary hypertension: A comprehensive review

Liberal, R; Grant, CR; Baptista, R; Macedo, G


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Positron emission tomography diagnostic imaging in multidrug-resistant hepatocellular carcinoma: focus on 2-deoxy-2-(18F)Fluoro-D-Glucose.

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Mol Diagn Ther. 2014 Oct;18(5):495-504

Potential cardiovascular risk protection of bilirubin in end-stage renal disease patients under hemodialysis.

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Practices in prescribing protein substitutes for PKU in Europe: No uniformity of approach.

Aguiar A, Ahring K, Almeida MF, Assoun M, Belanger Quintana A, Bigot S, Diels M, Dokupil K, Dubois S, Eftring K, Ekengren J, Ellerton C, Evans S, Faria A, et al.

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Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.

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Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

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Preventive stenting in acute myocardial infarction.

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Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation.

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Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a human keratinocyte cell line.

Almeida IF, Pinto AS, Monteiro C, Monteiro H, Belo L, Fernandes J, Bento AR, Duarte TL, Garrido J, Bahia MF, Sousa Lobo JM, Costa PC.

J Photochem Photobiol B. 2015 Jan 29;144C:28-34

Psychomotor retardation and vulnerability to interferon alpha induced major depressive disorder: Prospective study of a chronic hepatitis C cohort.

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J Psychosom Res. 2015 Jun 18.

Quality indicators in rheumatoid arthritis: results from the METEOR database.

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Rheumatology (Oxford). 2015 Apr 14

Quercetin in Cancer Treatment, Alone or in Combination with Conventional Therapeutics?

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Current Medicinal Chemistry, 22 (26):3025-3039; 2015

Radiographic evaluation of conical tapered platform-switched implants in the posterior mandible: 1-year results of a two-center prospective study.

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Clin Oral Implants Res. 2015 Jun 21.

Radiotherapy metabolic with 131I, a new promise for cholangiocarcinoma treatment?

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European Journal of Nuclear Medicine and Molecular Imaging, 42 S500-S500; 1 OCT 2015

Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron status in the rat.

Ribeiro S, Garrido P, Fernandes J, Rocha S, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.

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Reflection impulsivity in binge drinking: behavioural and volumetric correlates.

Banca P, Lange I, Worbe Y, Howell NA, Irvine M, Harrison NA, Moutoussis M, Voon V.

Addict Biol. 2015 Feb 11

Renal replacement therapy in Europe: a summary of the 2012 ERA-EDTA Registry Annual Report.

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Investigative Ophthalmology & Visual Science, 56 (7): jun 2015

RETINAL ANGIOMATOUS PROLIFERATION: A Quantitative Analysis of the Fundoscopic Features of the Fellow Eye.

Marques JP, Laíns I, Costa MÂ, Pires I, da Luz Cachulo M, Figueira J, Silva R.

Retina. 2015 Oct;35(10):1985-91.

Retinoblastoma: might photodynamic therapy be an option?

Teixo R, Laranjo M, Abrantes AM, Brites G, Serra A, Proença R, Botelho MF.

Cancer Metastasis Rev. 2015 Jan 13

RNA/DNA co-analysis from human skin and contact traces - results of a sixth collaborative EDNAP exercise.

Haas C, Hanson E, Banemann R, Bento AM, Berti A, Carracedo Á, et al.

Forensic Sci Int Genet. 2015 Jan 7;16C:139-147.

Safety of Glucocorticoids in Rheumatoid Arthritis: Evidence from Recent Clinical Trials

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Neuroimmunomodulation. 2015;22(1-2):57-65

Safety profiles of adalimumab, etanercept and infliximab: a pharmacovigilance study using a measure of disproportionality in a database of spontaneously reported adverse events.

Mendes D, Alves C, Batel-Marques F.

J Clin Pharm Ther. 2014 Jun;39(3):307-13.

Screening for Diabetic Retinopathy in the Central Region of Portugal. Added Value of Automated 'Disease/No Disease' Grading

Ribeiro, L; Oliveira, CM; Neves, C; Ramos, JD; Ferreira, H; Cunha-Vaz, J

OPHTHALMOLOGICA, 233 (2):96-103; 10.1159/000368426 2015

Second primary cancers in uveal melanoma survivors and the role of radiotherapy: a long-term population-based study

Lains, I; Bartosch, C; Mondim, V; Husain, D; Miller, JW

Investigative Ophthalmology & Visual Science, 56 (7):JUN 2015

Secondary tricuspid valve regurgitation: a forgotten entity.

Tornos Mas P, Rodríguez-Palomares JF, Antunes MJ.

Heart. 2015 Nov;101(22):1840-8.

Self-assembling systems based on quaternized derivatives of 1,4-diazabicyclo[2.2.2]octane in nutrient broth as antimicrobial agents and carriers for hydrophobic drugs.

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Colloids Surf B Biointerfaces. 2015 Feb 3;127C:266-273

Senescent bronchial fibroblasts induced to senescence by Cr(VI) promote

epithelial-mesenchymal transition when co-cultured with bronchial epithelial cells in the presence of Cr(VI)

Val, MM; Mendes, LA; Alarcao, A; Carvalho, L; Carreira, I; Rodrigues, CFD; Alpoim, MC

MUTAGENESIS, 30 (2):277-286; 10.1093/mutage/geu070 MAR 2015

Sensitization to palladium and nickel in Europe and the relationship with oral disease and dental alloys

Muris, J; Goossens, A; Goncalo, M; Bircher, AJ; Gimenez-Arnau, A; Foti, C; Rustemeyer, T; Feilzer, AJ; Kleverlaan, CJ

CONTACT DERMATITIS, 72 (5):286-296; 10.1111/cod.12327 MAY 2015

Sensitization to palladium in Europe

Muris, J; Goossens, A; Goncalo, M; Bircher, AJ; Gimenez-Arnau, A; Foti, C; Bruze, M; Andersen, KE; Rustemeyer, T; Feilzer, AJ; Kleverlaan, CJ

Contact Dermatitis, 72 (1):11-19; 10.1111/cod.12295 JAN 2015

Sensitizing osteosarcoma stem cells to doxorubicin-induced apoptosis through retention of doxorubicin and modulation of apoptotic-related proteins.

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Life Sci. 2015 Mar 25. pii: S0024-3205(15)00162-9

Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets

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Pedreiro, S; Martinho, A; Trindade, H; Young, HA; da Silva, JAP; Paiva, A

JOURNAL OF INFLAMMATION-LONDON, 12 10.1186/s12950-015-0083-2 MAY 23 2015

Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets.

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J Inflamm (Lond). 2015 May 23;12:38.

Sex estimation from the tarsal bones in a Portuguese sample: a machine learning approach

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Sildenafil acutely decreases visual responses in ON and OFF retinal ganglion cells.

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Invest Ophthalmol Vis Sci. 2015 Mar 26.

Sirtuins: double players in Huntington's disease.

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Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2183-94

Sitagliptin inhibits neuroinflammatory processes in retinal microglia

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Investigative Ophthalmology & Visual Science, 56 (7): Jun 2015

Solvent Accessible Surface Area-Based Hot-Spot Detection Methods for Protein-Protein and Protein-Nucleic Acid Interfaces

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Sonication-Assisted Layer-by-Layer Assembly for Low Solubility Drug Nanoformulation.

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ACS Appl Mater Interfaces. 2015 May 27

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Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts.

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Toxicology. 2015 May 18;334:1-11

Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype.

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Supramitral membrane mimicking posterior mitral valve prolapse.

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Eur J Cardiothorac Surg. 2015 Sep;48(3):e60-1.

Synthesis, characterization and biomolecule-binding properties of novel tetra-platinum(II)-thiopyridylporphyrins

Lourenco, LMO; Iglesias, BA; Pereira, PMR; Girao, H; Fernandes, R; Neves, MGPMS; Cavaleiro, JAS; Tome, JPC

Dalton Transactions, 44 (2):530-538; 10.1039/c4dt02697g 2015

The accuracy of osteoporotic fracture risk prediction tools: a systematic review and meta-analysis.

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Ann Rheum Dis. 2015 Nov;74(11):1958-67

The burden of osteoporotic hip fractures in Portugal: costs, health related quality of life and mortality

Marques, A; Lourenco, O; da Silva, JAP

Osteoporos Int. 2015 Nov;26(11):2623-30.

The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases.

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The Distinct Role of the Amygdala, Superior Colliculus and Pulvinar in Processing of Central and Peripheral Snakes.

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PLoS One. 2015 Jun 15;10(6):e0129949

The dual facet of gamma oscillations: separate visual and decision making circuits as revealed by simultaneous EEG/fMRI.

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The effectiveness of a resorbable bone substitute with a resorbable membrane in the treatment of periodontal infrabony defect - A multicenter randomised controlled trial.

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The Effects of Different Concentrations of the alpha(2)-Adrenoceptor Agonist Medetomidine on Basal Excitatory Synaptic Transmission and Synaptic Plasticity in Hippocampal Slices of Adult Mice

Ribeiro, PO; Antunes, LM; Nunes, CS; Silva, HB; Cunha, RA; Tome, AR

ANESTHESIA AND ANALGESIA, 120 (5):1130-1137; MAY 2015

The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs

Santana I, Farinha F, Freitas S, Rodrigues V, Carvalho Ã.

Acta Med Port. 2015 Mar-Apr;28(2):182-188.

The free and cued selective reminding test distinguishes frontotemporal dementia from Alzheimer's disease.

Lemos R, Duro D, Simões MR, Santana I.

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The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study.

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The germline CDH1 c.48 G&gt;C substitution contributes to cancer predisposition through generation of a pro-invasive mutation.

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The need for patient-focused therapy for children and teenagers with allergic rhinitis: a case-based review of current European practice.

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Clin Transl Allergy. 2015 Jan 24;5(1):2

The other side of recovery: validation of the Portuguese version of the subjective experiences of psychosis scale.

Martins F, Soares SC, Bem-Haja P, Roque C, Madeira N.

BMC Psychiatry. 2015 Oct 14;15:246

The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class?

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The Range of Fovea! Avascular Zone (FAZ) Size and Vessel Density Around the FAZ in Healthy Eyes as Measured from OCT Angiography En-Face Images

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The role of hybrid chitosan membranes on scarring process following lumbar surgery: post-laminectomy experimental model

Carvalho, M; Costa, LM; Pereira, JE; Shirosaki, Y; Hayakawa, S; Santos, JD; Geuna, S; Fregnan, F; Cabrita, AM; Mauricio, AC; Varejao, AS

Neurological Research, 37 (1):23-29; 10.1179/1743132814y. jan2015

The role of percutaneous renal fenestration in the management of acute aortic dissection. Case report.

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The TNF-α/NF-κB signaling pathway has a key role in methamphetamine-induced blood-brain barrier dysfunction.

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J Cereb Blood Flow Metab. 2015 Apr 22

The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm

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Mol Neurobiol. 2015, Dec;52(3):1804-20.

The Use of Natural Polysaccharides as Biomaterials.

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Biomed Res Int. 2015;2015:242378

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Therapeutic and Nutraceutical Potential of Rosmarinic Acid - Cytoprotective Properties and Pharmacokinetic Profile.

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Crit Rev Food Sci Nutr. 2015 Jun 26:0.

Three-dimensional segmentation and reconstruction of the retinal vasculature from spectral-domain optical coherence tomography.

Guimarães P, Rodrigues P, Celorico D, Serranho P, Bernardes R.

J Biomed Opt. 2015 Jan 1;20(1):16006

Ticks on passerines from the Archipelago of the Azores as hosts of borreliae and rickettsiae.

Literak I, Norte AC, Núncio MS, de Carvalho IL, Ogrzewalska M, Nováková M, Martins TF, Sychra O, Resendes R, Rodrígues P.

Ticks Tick Borne Dis. 2015 May 11

To beat or not to beat: degradation of Cx43 imposes the heart rhythm.

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Biochem Soc Trans. 2015 Jun 1;43(3):476-81

Tobacco influence in the clinical progression of multiple sclerosis

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TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy.

Canhão H, Rodrigues AM, Santos MJ, Carmona-Fernandes D, Bettencourt BF, Cui J, Rocha FL, Canas Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araujo D, Silva C, Santos H, Duarte C, et al.

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Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats

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Investigative Ophthalmology & Visual Science, 56 (8):4309-4323; 10.1167/iovs.15-16963 JUL 2015

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice

Mendonca, LS; Nobrega, C; Hirai, H; Kaspar, BK; de Almeida, LP

BRAIN, 138 320-335; 10.1093/brain/awu352 2 FEB 1 2015

Triosephosphate isomerase gene promoter variation: -5G/A and -8G/A polymorphisms in clinical malaria groups in two African populations.

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Infect Genet Evol. 2015 Mar 20.

Tumor necrosis factor-related apoptosis-inducing ligand and death receptors: relevance in the pathogenesis of monoclonal gammopathies

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Haematologica, 100 499-500; 1 JUN 2015

Type 2 Diabetes Aggravates Alzheimer's Disease-Associated Vascular Alterations of the Aorta in Mice

Sena, CM; Pereira, AM; Carvalho, C; Fernandes, R; Seica, RM; Oliveira, CR; Moreira, PI

JOURNAL OF ALZHEIMERS DISEASE, 45 (1):127-138; 10.3233/JAD-141008 2015

Tyrosine kinase inhibitor therapy induces alterations of cd137 and cd137l expression in chronic myeloid leukemia patients

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Haematologica, 100 431-432; 1 JUN 2015

Universal Definition of Myocardial Infarction: Clinical Insights

Paiva, L; Providencia, R; Barra, S; Dinis, P; Faustino, AC; Goncalves, L

CARDIOLOGY, 131 (1):13-21; 10.1159/000371739 2015

Use of implantable cardioverter-defibrillators in athletes: A systematic review.

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Validation studies of the Clock Drawing Test in mild cognitive impairment

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European Journal of Neurology, 22 496-496; 1 si jun 2015

Visual areas PPA and pSTS diverge from other processing modules during perceptual closure: Functional dichotomies within category selective networks (vol 61, pg 135, 2014)

Rebola, Jose; Castelo-Branco, Miguel

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Who are the patients with extrapulmonary tuberculosis?

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