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IIIUC

Instituto de Investigação Interdisciplinar

Pharmacology & Toxicology (48)

Title : Adenosine A(2A) receptors are necessary and sufficient to trigger memory impairment in adult mice
Author(s): Pagnussat, N; Almeida, AS; Marques, DM; Nunes, F; Chenet, GC; Botton, PHS; Mioranzza, S; Loss, CM; Cunha, RA; Porciuncula, LO
Source : BRITISH JOURNAL OF PHARMACOLOGY Document Type : Article Volume : 172 Issue: 15 Pages: 3831-3845 DOI: 10.1111/bph.13180 Published: 2015 AUG
Times Cited: 7
 
Title : Antifungal activity of the essential oil of Angelica major against Candida, Cryptococcus, Aspergillus and dermatophyte species
Author(s): Cavaleiro, C; Salgueiro, L; Goncalves, MJ; Hrimpeng, K; Pinto, J; Pinto, E
Source : JOURNAL OF NATURAL MEDICINES Document Type : Article Volume : 69 Issue: 2 Pages: 241-248 DOI: 10.1007/s11418-014-0884-2 Published: 2015 APR
Times Cited: 6
 
Title : Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory doses
Author(s): Abu-Darwish, MS; Cabral, C; Goncalves, MJ; Cavaleiro, C; Cruz, MT; Efferth, T; Salgueiro, L
Source : JOURNAL OF ETHNOPHARMACOLOGY Document Type : Article Volume : 174 Issue: Pages: 153-160 DOI: 10.1016/j.jep.2015.08.005 Published: 2015 NOV 4
Times Cited: 4
 
Title : Assessing the Effects on Clinical Outcomes of an Outsourced Pharmaceutical Care Service in Portuguese Community Pharmacies
Author(s): Condinho, M; Fernandez-Llimos, F; Figueiredo, IV; Sinogas, C
Source : LATIN AMERICAN JOURNAL OF PHARMACY Document Type : Article Volume : 34 Issue: 4 Pages: 782-789 DOI: Published: 2015
Times Cited: 0
 
Title : Biopharmaceutical profile of pranoprofen-loaded PLGA nanoparticles containing hydrogels for ocular administration
Author(s): Abrego, G; Alvarado, H; Souto, EB; Guevara, B; Bellowa, LH; Parra, A; Calpena, A; Garcia, ML
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 95 Issue: Pages: 261-270 DOI: 10.1016/j.ejpb.2015.01.026 Published: 2015 SEP
Times Cited: 11
 
Title : Bone critical defect repair with poloxamine-cyclodextrin supramolecular gels
Author(s): del Rosario, C; Rodriguez-Evora, M; Reyes, R; Simoes, S; Concheiro, A; Evora, C; Alvarez-Lorenzo, C; Delgado, A
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 495 Issue: 1 Pages: 463-473 DOI: 10.1016/j.ijpharm.2015.09.003 Published: 2015 NOV 10
Times Cited: 2
 
Title : Current nanotechnology approaches for the treatment and management of diabetic retinopathy
Author(s): Fangueiro, JF; Silva, AM; Garcia, ML; Souto, EB
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 95 Issue: Pages: 307-322 DOI: 10.1016/j.ejpb.2014.12.023 Published: 2015 SEP
Times Cited: 3
 
Title : Development and characterization of a cationic lipid nanocarrier as non-viral vector for gene therapy
Author(s): Severino, P; Szymanski, M; Favaro, M; Azzoni, AR; Chaud, MV; Santana, MHA; Silva, AM; Souto, EB
Source : EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES Document Type : Article Volume : 66 Issue: Pages: 78-82 DOI: 10.1016/j.ejps.2014.09.021 Published: 2015 JAN 23
Times Cited: 9
 
Title : Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity
Author(s): Bento, D; Staats, HF; Goncalves, T; Borges, O
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 93 Issue: Pages: 149-164 DOI: 10.1016/j.ejpb.2015.03.024 Published: 2015 JUN
Times Cited: 12
 
Title : Didanosine-loaded chitosan microspheres optimized by surface-response methodology: A modified Maximum Likelihood Classification'' approach formulation for reverse transcriptase inhibitors
Author(s): da Silva, CF; Severino, P; Martins, F; Santana, MHA; Souto, EB
Source : BIOMEDICINE & PHARMACOTHERAPY Document Type : Article Volume : 70 Issue: Pages: 46-52 DOI: 10.1016/j.biopha.2014.12.047 Published: 2015 MAR
Times Cited: 0
 
Title : Direct nose-to-brain delivery of lamotrigine following intranasal administration to mice
Author(s): Serralheiro, A; Alves, G; Fortuna, A; Falcao, A
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 490 Issue: 1-2 Pages: 39-46 DOI: 10.1016/j.ijpharm.2015.05.021 Published: 2015 JUL 25
Times Cited: 6
 
Title : Drug-related problems in institutionalized, polymedicated elderly patients: opportunities for pharmacist intervention
Author(s): Silva, C; Ramalho, C; Luz, I; Monteiro, J; Fresco, P
Source : INTERNATIONAL JOURNAL OF CLINICAL PHARMACY Document Type : Article Volume : 37 Issue: 2 Pages: 327-334 DOI: 10.1007/s11096-014-0063-2 Published: 2015 APR
Times Cited: 7
 
Title : Effect of mucoadhesive polymers on the in vitro performance of insulin-loaded silica nanoparticles: Interactions with mucin and biomembrane models
Author(s): Andreani, T; Miziara, L; Lorenzon, EN; de Souza, ALR; Kiill, CP; Fangueiro, JF; Garcia, ML; Gremiao, PD; Silva, AM; Souto, EB
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 93 Issue: Pages: 118-126 DOI: 10.1016/j.ejpb.2015.03.027 Published: 2015 JUN
Times Cited: 9
 
Title : Effects of the extract and glycoalkaloids of Solanum lycocarpum St. Hill on Giardia lamblia trophozoites
Author(s): Martins, GZ; Moreira, RRD; Planeta, CS; Almeida, AE; Bastos, JK; Salgueiro, L; Cavaleiro, C; Sousa, MD
Source : PHARMACOGNOSY MAGAZINE Document Type : Article Volume : 11 Issue: 42 Pages: S161-S165 DOI: 10.4103/0973-1296.157721 Published: 2015 MAY
Times Cited: 2
 
Title : ERK1/2 acts as a switch between necrotic and apoptotic cell death in ether phospholipid edelfosine-treated glioblastoma cells
Author(s): Melo-Lima, S; Lopes, MC; Mollinedo, F
Source : PHARMACOLOGICAL RESEARCH Document Type : Article Volume : 95-96 Issue: Pages: 2-11 DOI: 10.1016/j.phrs.2015.02.007 Published: 2015 MAY-JUN
Times Cited: 5
 
Title : Essential Oils as Active Ingredients of Lipid Nanocarriers for Chemotherapeutic Use
Author(s): Severino, P; Andreani, T; Chaud, MV; Benites, CI; Pinho, SC; Souto, EB
Source : CURRENT PHARMACEUTICAL BIOTECHNOLOGY Document Type : Article Volume : 16 Issue: 4 Pages: 365-370 DOI: Published: 2015
Times Cited: 3
 
Title : Evaluation of Opicapone on Cardiac Repolarization in a Thorough QT/QTc Study
Author(s): Pinto, R; l'Hostis, P; Patat, A; Homery, MC; Falcao, A; Nunes, T; Rocha, JF; Soares-da-Silva, P
Source : CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT Document Type : Article Volume : 4 Issue: 6 Pages: 454-462 DOI: 10.1002/cpdd.188 Published: 2015 NOV-DEC
Times Cited: 4
 
Title : Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis
Author(s): Rufino, AT; Ribeiro, M; Sousa, C; Judas, F; Salgueiro, L; Cavaleiro, C; Mendes, AF
Source : EUROPEAN JOURNAL OF PHARMACOLOGY Document Type : Article Volume : 750 Issue: Pages: 141-150 DOI: 10.1016/j.ejphar.2015.01.018 Published: 2015 MAR 5
Times Cited: 11
 
Title : FeCl3/Ultrasound Mediated Reaction of 2-aminothiophenol with Aldehydes in Water: Synthesis of 2-substituted Benzothiazoles of Pharmacological Interest
Author(s): Srinivas, PTVA; Bhavani, S; Rambabu, D; Rao, MVB; Kapavarapu, R; Pal, M
Source : LETTERS IN DRUG DESIGN & DISCOVERY Document Type : Article Volume : 12 Issue: 6 Pages: 457-465 DOI: Published: 2015
Times Cited: 0
 
Title : Gastroprotective effect of Cymbopogon citratus infusion on acute ethanol-induced gastric lesions in rats
Author(s): Sagradas, J; Costa, G; Figueirinha, A; Castel-Branco, MM; Cabrita, AMS; Figueiredo, IV; Batista, MT
Source : JOURNAL OF ETHNOPHARMACOLOGY Document Type : Article Volume : 173 Issue: Pages: 134-138 DOI: 10.1016/j.jep.2015.07.001 Published: 2015 SEP 15
Times Cited: 1
 
Title : Gemini Surfactants Mediate Efficient Mitochondrial Gene Delivery and Expression
Author(s): Cardoso, AM; Morais, CM; Cruz, AR; Cardoso, AL; Silva, SG; do Vale, ML; Marques, EF; de Lima, MCP; Jurado, AS
Source : MOLECULAR PHARMACEUTICS Document Type : Article Volume : 12 Issue: 3 Pages: 716-730 DOI: 10.1021/mp5005349 Published: 2015 MAR
Times Cited: 7
 
Title : Generation of hydrate forms of paroxetine HCl from the amorphous state: An evaluation of thermodynamic and experimental predictive approaches
Author(s): Pina, MF; Pinto, JF; Sousa, JJ; Craig, DQM; Zhao, M
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 481 Issue: 1-2 Pages: 114-124 DOI: 10.1016/j.ijpharm.2014.12.033 Published: 2015 MAR 15
Times Cited: 2
 
Title : Glycation and Hypoxia: Two Key Factors for Adipose Tissue Dysfunction
Author(s): Matafome, P; Rodrigues, T; Seica, R
Source : CURRENT MEDICINAL CHEMISTRY Document Type : Article Volume : 22 Issue: 20 Pages: 2417-2437 DOI: Published: 2015
Times Cited: 2
 
Title : High frequency and founder effect of the CYP3A4*20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme
Author(s): Apellaniz-Ruiz, M; Inglada-Perez, L; Naranjo, MEG; Sanchez, L; Mancikova, V; Curras-Freixes, M; de Cubas, AA; Comino-Mendez, I; Triki, S; Rebai, A; Rasool, M; Moya, G; Grazina, M; Opocher, G; Cascon,
Source : PHARMACOGENOMICS JOURNAL Document Type : Article Volume : 15 Issue: 3 Pages: 288-292 DOI: 10.1038/tpj.2014.67 Published: 2015 JUN
Times Cited: 2
 
Title : MicroRNAs in Glioblastoma: Role in Pathogenesis and Opportunities for Targeted Therapies
Author(s): Costa, PM; Cardoso, AL; Mano, M; de Lima, MCP
Source : CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS Document Type : Article Volume : 14 Issue: 2 Pages: 222-238 DOI: Published: 2015
Times Cited: 9
 
Title : MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma
Author(s): Costa, PM; Cardoso, AL; Custodia, C; Cunha, P; de Almeida, LP; de Lima, MCP
Source : JOURNAL OF CONTROLLED RELEASE Document Type : Article Volume : 207 Issue: Pages: 31-39 DOI: 10.1016/j.jconrel.2015.04.002 Published: 2015 JUN 10
Times Cited: 29
 
Title : Mitochondrial Dysfunction on the Toxic Effects of Anticancer Agents- From Lab Bench to Bedside
Author(s): Ribeiro, MPC; Santos, AECE; Custodio, JBA
Source : TOXICOLOGY STUDIES - CELLS, DRUGS AND ENVIRONMENT Document Type : Article; Book Chapter Volume : Issue: Pages: 23-59 DOI: 10.5772/59488 Published: 2015
Times Cited: 0
 
Title : Mitochondrial Mechanisms of Metabolic Reprogramming in Proliferating Cells
Author(s): Sousa, MI; Rodrigues, AS; Pereira, S; Perestrelo, T; Correia, M; Ramalho-Santos, J
Source : CURRENT MEDICINAL CHEMISTRY Document Type : Article Volume : 22 Issue: 20 Pages: 2493-2504 DOI: Published: 2015
Times Cited: 2
 
Title : Modulation of Endoplasmic Reticulum Stress: An Opportunity to Prevent Neurodegeneration?
Author(s): Placido, AI; Pereira, CMF; Duarte, AI; Candeias, E; Correia, SC; Carvalho, C; Cardoso, S; Oliveira, CR; Moreira, PI
Source : CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS Document Type : Article; Proceedings Paper Volume : 14 Issue: 4 Pages: 518-533 DOI: Published: 2015
Times Cited: 7
 
Title : Nasal Vaccines Against Hepatitis B: An Update
Author(s): Almeida, MS; Borges, O
Source : CURRENT PHARMACEUTICAL BIOTECHNOLOGY Document Type : Article Volume : 16 Issue: 10 Pages: 882-890 DOI: 10.2174/1389201016666150505122422 Published: 2015
Times Cited: 2
 
Title : New serine-derived gemini surfactants as gene delivery systems
Author(s): Cardoso, AM; Morals, CM; Cruz, AR; Silva, SG; do Vale, ML; Marques, EF; de Lima, MCP; Jurado, AS
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 89 Issue: Pages: 347-356 DOI: 10.1016/j.ejpb.2014.12.013 Published: 2015 JAN
Times Cited: 4
 
Title : Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review
Author(s): Simo, R; Ballarini, S; Cunha-Vaz, J; Ji, LN; Haller, H; Zimmet, P; Wong, TY
Source : CURRENT MEDICINAL CHEMISTRY Document Type : Article Volume : 22 Issue: 21 Pages: 2580-2589 DOI: Published: 2015
Times Cited: 2
 
Title : Novel serine-based gemini surfactants as chemical permeation enhancers of local anesthetics: A comprehensive study on structure-activity relationships, molecular dynamics and dermal delivery
Author(s): Teixeira, RS; Cova, TFGG; Silva, SMC; Oliveira, R; do Vale, MLC; Marques, EF; Pais, AACC; Veiga, FJB
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 93 Issue: Pages: 205-213 DOI: 10.1016/j.ejpb.2015.02.024 Published: 2015 JUN
Times Cited: 0
 
Title : Optimization of levofloxacin-loaded crosslinked chitosan microspheres for inhaled aerosol therapy
Author(s): Gaspar, MC; Sousa, JJS; Pais, AACC; Cardoso, O; Murtinho, D; Serra, MES; Tewes, F; Olivier, JC
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 96 Issue: Pages: 65-75 DOI: 10.1016/j.ejpb.2015.07.010 Published: 2015 OCT
Times Cited: 7
 
Title : Osteogenic poly(epsilon-caprolactone)/poloxamine homogeneous blends prepared by supercritical foaming
Author(s): de Matos, MBC; Puga, AM; Alvarez-Lorenzo, C; Concheiro, A; Braga, MEM; de Sousa, HC
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 479 Issue: Pages: 11-22 DOI: 10.1016/j.ijpharm.2014.12.041 Published: 2015 FEB 1
Times Cited: 2
 
Title : Overcoming the Skin Permeation Barrier: Challenges and Opportunities
Author(s): Vitorino, C; Sousa, J; Pais, A
Source : CURRENT PHARMACEUTICAL DESIGN Document Type : Article Volume : 21 Issue: 20 Pages: 2698-2712 DOI: Published: 2015
Times Cited: 2
 
Title : Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment
Author(s): Silva, CO; Rijo, P; Molpeceres, J; Figueiredo, IV; Ascensao, L; Fernandes, AS; Roberto, A; Reis, CP
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 493 Issue: 1-2 Pages: 271-284 DOI: 10.1016/j.ijpharm.2015.07.044 Published: 2015 SEP 30
Times Cited: 9
 
Title : Preparation of robust polyamide microcapsules by interfacial polycondensation of p-phenylenediamine and sebacoyl chloride and plasticization with oleic acid
Author(s): Rosa, N; Martins, GV; Bastos, MMSM; Gois, JR; Coelho, JFJ; Marques, J; Tavares, CJ; Magalhaes, FD
Source : JOURNAL OF MICROENCAPSULATION Document Type : Article Volume : 32 Issue: 4 Pages: 349-357 DOI: 10.3109/02652048.2015.1028494 Published: 2015
Times Cited: 1
 
Title : Presynaptic adenosine A(2A) receptors dampen cannabinoid CB1 receptor-mediated inhibition of corticostriatal glutamatergic transmission
Author(s): Ferreira, SG; Goncalves, FQ; Marques, JM; Tome, AR; Rodrigues, RJ; Nunes-Correia, I; Ledent, C; Harkany, T; Venance, L; Cunha, RA; Kofalvi, A
Source : BRITISH JOURNAL OF PHARMACOLOGY Document Type : Article Volume : 172 Issue: 4 Pages: 1074-1086 DOI: 10.1111/bph.12970 Published: 2015 FEB
Times Cited: 10
 
Title : Quality of life in pediatric asthma patients and their parents: a meta-analysis on 20 years of research
Author(s): Silva, N; Carona, C; Crespo, C; Canavarro, MC
Source : EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH Document Type : Article Volume : 15 Issue: 3 Pages: 499-519 DOI: 10.1586/14737167.2015.1008459 Published: 2015 JUN
Times Cited: 2
 
Title : Quercetin in Cancer Treatment, Alone or in Combination with Conventional Therapeutics?
Author(s): Brito, AF; Ribeiro, M; Abrantes, AM; Pires, AS; Teixo, RJ; Tralhao, JG; Botelho, MF
Source : CURRENT MEDICINAL CHEMISTRY Document Type : Article Volume : 22 Issue: 26 Pages: 3025-3039 DOI: 10.2174/0929867322666150812145435 Published: 2015
Times Cited: 12
 
Title : Regulation of Mitochondrial Function and its Impact in Metabolic Stress
Author(s): Duarte, FV; Amorim, JA; Palmeira, CM; Rolo, AP
Source : CURRENT MEDICINAL CHEMISTRY Document Type : Article Volume : 22 Issue: 20 Pages: 2468-2479 DOI: Published: 2015
Times Cited: 4
 
Title : Shutting Down the Furnace: Preferential Killing of Cancer Cells with Mitochondrial-Targeting Molecules
Author(s): Deus, CM; Santos, GL; Loureiro, R; Vega-Naredo, I; Faneca, H; Oliveira, PJ
Source : CURRENT MEDICINAL CHEMISTRY Document Type : Article Volume : 22 Issue: 20 Pages: 2438-2457 DOI: Published: 2015
Times Cited: 2
 
Title : Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts
Author(s): Deus, CM; Zehowski, C; Nordgren, K; Wallace, KB; Skildum, A; Oliveira, PJ
Source : TOXICOLOGY Document Type : Article Volume : 334 Issue: Pages: 1-11 DOI: 10.1016/j.tox.2015.05.001 Published: 2015 AUG 6
Times Cited: 1
 
Title : Sulfathiazole: Analytical methods for quantification in seawater and macroalgae
Author(s): Leston, S; Nebot, C; Nunes, M; Cepeda, A; Pardal, MA; Ramos, F
Source : ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY Document Type : Article Volume : 39 Issue: 1 Pages: 77-84 DOI: 10.1016/j.etap.2014.11.007 Published: 2015 JAN
Times Cited: 3
 
Title : Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells
Author(s): Goncalo, M; Martins, J; Silva, A; Neves, B; Figueiredo, A; Cruz, T; Lopes, C
Source : JOURNAL OF APPLIED TOXICOLOGY Document Type : Article Volume : 35 Issue: 4 Pages: 398-406 DOI: 10.1002/jat.3033 Published: 2015 APR
Times Cited: 2
 
Title : Transport properties in aqueous ethambutol dihydrochloride
Author(s): Verissimo, LMP; Cabral, AMTDPV; Veiga, FJB; Almeida, SFG; Ramos, ML; Burrows, HD; Esteso, MA; Ribeiro, ACF
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 479 Issue: 2 Pages: 306-311 DOI: 10.1016/j.ijpharm.2014.12.053 Published: 2015 FEB 20
Times Cited: 4
 
Title : Validation of an UV spectrophotometric assay for the quantification of polymyxin B in solid lipid nanoparticles
Author(s): Severino, P; Silveira, EF; Vazzana, M; Chaud, MV; Santana, MHA; Souto, EB
Source : PHARMAZIE Document Type : Article Volume : 70 Issue: 11 Pages: 693-697 DOI: 10.1691/ph.2015.5073 Published: 2015 NOV
Times Cited: 0