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IIIUC

Instituto de Investigação Interdisciplinar

Neuroscience & Behavior

Title : Adenosine A(2A) receptors modulate glutamate uptake in cultured astrocytes and gliosomes
Author(s): Matos, M; Augusto, E; Dos Santos-Rodrigues, A; Schwarzschild, MA; Chen, JF; Cunha, RA; Agostinho, P
Source : GLIA Document Type : Article Volume : 60 Issue: 5 Pages: 702-716 DOI: 10.1002/glia.22290 Published: 2012 MAY
Times Cited: 51
 
Title : Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures
Author(s): Schitine, C; Xapelli, S; Agasse, F; Sarda-Arroyo, L; Silva, AP; Reis, RAD; de Mello, FG; Malva, JO
Source : EUROPEAN JOURNAL OF NEUROSCIENCE Document Type : Article Volume : 35 Issue: 11 Pages: 1672-1683 DOI: 10.1111/j.1460-9568.2012.08072.x Published: 2012 JUN
Times Cited: 3
 
Title : Amyloid beta-induced ER stress is enhanced under mitochondrial dysfunction conditions
Author(s): Costa, RO; Ferreiro, E; Martins, I; Santana, I; Cardoso, SM; Oliveira, CR; Pereira, CMF
Source : NEUROBIOLOGY OF AGING Document Type : Article Volume : 33 Issue: 4 Pages: - DOI: 10.1016/j.neurobiolaging.2011.04.011 Published: 2012 APR
Times Cited: 3
 
Title : Basal ganglia, thalamus and neocortical atrophy predicting slowed cognitive processing in multiple sclerosis
Author(s): Batista, S; Zivadinov, R; Hoogs, M; Bergsland, N; Heininen-Brown, M; Dwyer, MG; Weinstock-Guttman, B; Benedict, RHB
Source : JOURNAL OF NEUROLOGY Document Type : Article Volume : 259 Issue: 1 Pages: 139-146 DOI: 10.1007/s00415-011-6147-1 Published: 2012 JAN
Times Cited: 111
 
Title : Blockade of adenosine A(2A) receptors prevents interleukin-1 beta-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway
Author(s): Simoes, AP; Duarte, JA; Agasse, F; Canas, PM; Tome, AR; Agostinho, P; Cunha, RA
Source : JOURNAL OF NEUROINFLAMMATION Document Type : Article Volume : 9 Issue: Pages: - DOI: 10.1186/1742-2094-9-204 Published: 2012 AUG 20
Times Cited: 14
 
Title : Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease
Author(s): Simoes, AT; Goncalves, N; Koeppen, A; Deglon, N; Kugler, S; Duarte, CB; de Almeida, LP
Source : BRAIN Document Type : Article Volume : 135 Issue: Pages: 2428-2439 DOI: 10.1093/brain/aws177 Published: 2012 AUG
Times Cited: 37
 
Title : CB1 receptor activation inhibits neuronal and astrocytic intermediary metabolism in the rat hippocampus
Author(s): Duarte, JMN; Ferreira, SG; Carvalho, RA; Cunha, RA; Kofalvi, A
Source : NEUROCHEMISTRY INTERNATIONAL Document Type : Article Volume : 60 Issue: 1 Pages: 1-8 DOI: 10.1016/j.neuint.2011.10.019 Published: 2012 JAN
Times Cited: 8
 
Title : Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose
Author(s): Costa, GN; Vindeirinho, J; Cavadas, C; Ambrosio, AF; Santos, PF
Source : MOLECULAR AND CELLULAR NEUROSCIENCE Document Type : Article Volume : 50 Issue: 1 Pages: 113-123 DOI: 10.1016/j.mcn.2012.04.003 Published: 2012 MAY
Times Cited: 16
 
Title : Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1 alpha
Author(s): Correia, SC; Santos, RX; Cardoso, SM; Santos, MS; Oliveira, CR; Moreira, PI
Source : NEUROBIOLOGY OF DISEASE Document Type : Article Volume : 45 Issue: 1 Pages: 206-218 DOI: 10.1016/j.nbd.2011.08.005 Published: 2012 JAN
Times Cited: 19
 
Title : Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice
Author(s): Pereira, FC; Cunha-Oliveira, T; Viana, SD; Travassos, AS; Nunes, S; Silva, C; Prediger, RD; Rego, AC; Ali, SF; Ribeiro, CAF
Source : NEUROTOXICOLOGY AND TERATOLOGY Document Type : Article Volume : 34 Issue: 5 Pages: 522-529 DOI: 10.1016/j.ntt.2012.07.005 Published: 2012 SEP-OCT
Times Cited: 10
 
Title : Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series
Author(s): McNaughton, D; Knight, W; Guerreiro, R; Ryan, N; Lowe, J; Poulter, M; Nicholl, DJ; Hardy, J; Revesz, T; Lowe, J; Rossor, M; Collinge, J; Mead, S
Source : NEUROBIOLOGY OF AGING Document Type : Article Volume : 33 Issue: 2 Pages: - DOI: 10.1016/j.neurobiolaging.2010.10.010 Published: 2012 FEB
Times Cited: 8
 
Title : Dynamic Causal Modelling of epileptic seizure propagation pathways: A combined EEG-fMRI study
Author(s): Murta, T; Leal, A; Garrido, MI; Figueiredo, P
Source : NEUROIMAGE Document Type : Article Volume : 62 Issue: 3 Pages: 1634-1642 DOI: 10.1016/j.neuroimage.2012.05.053 Published: 2012 SEP
Times Cited: 30
 
Title : ELEVATED GLUCOSE CONCENTRATION CHANGES THE CONTENT AND CELLULAR LOCALIZATION OF AMPA RECEPTORS ON THE RETINA BUT NOT IN THE HIPPOCAMPUS
Author(s): Castilho, AF; Liberal, JT; Baptista, FI; Gaspar, JM; Carvalho, AL; Ambrosio, AF
Source : NEUROSCIENCE Document Type : Article Volume : 219 Issue: Pages: 23-32 DOI: 10.1016/j.neuroscience.2012.05.056 Published: 2012 SEP 6
Times Cited: 10
 
Title : EPIGENETIC REGULATION OF BACE1 IN ALZHEIMER'S DISEASE PATIENTS AND IN TRANSGENIC MICE
Author(s): Marques, SCF; Lemos, R; Ferreiro, E; Martins, M; de Mendonca, A; Santana, I; Outeiro, TF; Pereira, CMF
Source : NEUROSCIENCE Document Type : Article Volume : 220 Issue: Pages: 256-266 DOI: 10.1016/j.neuroscience.2012.06.029 Published: 2012 SEP 18
Times Cited: 26
 
Title : Evaluation of the permeability and P-glycoprotein efflux of carbamazepine and several derivatives across mouse small intestine by the Ussing chamber technique
Author(s): Fortuna, A; Alves, G; Falcao, A; Soares-da-Silva, P
Source : EPILEPSIA Document Type : Article Volume : 53 Issue: 3 Pages: 529-538 DOI: 10.1111/j.1528-1167.2012.03409.x Published: 2012 MAR
Times Cited: 15
 
Title : Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons
Author(s): Gomes, JR; Costa, JT; Melo, CV; Felizzi, F; Monteiro, P; Pinto, MJ; Inacio, AR; Wieloch, T; Almeida, RD; Graos, M; Duarte, CB
Source : JOURNAL OF NEUROSCIENCE Document Type : Article Volume : 32 Issue: 13 Pages: 4610-4622 DOI: 10.1523/JNEUROSCI.0374-12.2012 Published: 2012 MAR 28
Times Cited: 36
 
Title : Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease
Author(s): Guerreiro, RJ; Lohmann, E; Kinsella, E; Bras, JM; Luu, N; Gurunlian, N; Dursun, B; Bilgic, B; Santana, I; Hanagasi, H; Gurvit, H; Gibbs, JR; Oliveira, C; Emre, M; Singleton, A
Source : NEUROBIOLOGY OF AGING Document Type : Article Volume : 33 Issue: 5 Pages: - DOI: 10.1016/j.neurobiolaging.2011.10.009 Published: 2012 MAY
Times Cited: 6
 
Title : Glutathione S-Transferase pi Mediates MPTP-Induced c-Jun N-Terminal Kinase Activation in the Nigrostriatal Pathway
Author(s): Castro-Caldas, M; Carvalho, AN; Rodrigues, E; Henderson, C; Wolf, CR; Gama, MJ
Source : MOLECULAR NEUROBIOLOGY Document Type : Article Volume : 45 Issue: 3 Pages: 466-477 DOI: 10.1007/s12035-012-8266-9 Published: 2012 JUN
Times Cited: 20
 
Title : Histamine modulates microglia function
Author(s): Ferreira, R; Santos, T; Goncalves, J; Baltazar, G; Ferreira, L; Agasse, F; Bernardino, L
Source : JOURNAL OF NEUROINFLAMMATION Document Type : Article Volume : 9 Issue: Pages: - DOI: 10.1186/1742-2094-9-90 Published: 2012 MAY 8
Times Cited: 27
 
Title : Identification of PSEN1 and PSEN2 gene mutations and variants in Turkish dementia patients
Author(s): Lohmann, E; Guerreiro, RJ; Erginel-Unaltuna, N; Gurunlian, N; Bilgic, B; Gurvit, H; Hanagasi, HA; Luu, N; Emre, M; Singleton, A
Source : NEUROBIOLOGY OF AGING Document Type : Article Volume : 33 Issue: 8 Pages: - DOI: 10.1016/j.neurobiolaging.2012.02.020 Published: 2012 AUG
Times Cited: 7
 
Title : Impaired hippocampal glucoregulation in the cannabinoid CB1 receptor knockout mice as revealed by an optimized in vitro experimental approach
Author(s): Lemos, C; Valerio-Fernandes, A; Ghisleni, GC; Ferreira, SG; Ledent, C; de Ceballos, ML; Kofalvi, A
Source : JOURNAL OF NEUROSCIENCE METHODS Document Type : Article Volume : 204 Issue: 2 Pages: 366-373 DOI: 10.1016/j.jneumeth.2011.11.028 Published: 2012 MAR 15
Times Cited: 4
 
Title : Intracellular mechanisms coupled to NPY Y-2 and Y-5 receptor activation and lipid accumulation in murine adipocytes
Author(s): Rosmaninho-Salgado, J; Cortez, V; Estrada, M; Santana, MM; Goncalves, A; Marques, AP; Cavadas, C
Source : NEUROPEPTIDES Document Type : Article Volume : 46 Issue: 6 Pages: 359-366 DOI: 10.1016/j.npep.2012.08.006 Published: 2012 DEC
Times Cited: 13
 
Title : Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment
Author(s): Goncalves, J; Baptista, S; Olesen, MV; Fontes-Ribeiro, C; Malva, JO; Woldbye, DP; Silva, AP
Source : JOURNAL OF NEUROCHEMISTRY Document Type : Article Volume : 123 Issue: 6 Pages: 1041-1053 DOI: 10.1111/jnc.12052 Published: 2012 DEC
Times Cited: 15
 
Title : Mitochondrial Abnormalities in Alzheimer's Disease: Possible Targets for Therapeutic Intervention
Author(s): Silva, DF; Selfridge, JE; Lu, J; Lezi, E; Cardoso, SM; Swerdlow, RH
Source : CURRENT STATE OF ALZHEIMER'S DISEASE RESEARCH AND THERAPEUTICS Document Type : Article; Book Chapter Volume : 64 Issue: Pages: 83-126 DOI: 10.1016/B978-0-12-394816-8.00003-9 Published: 2012
Times Cited: 26
 
Title : Mitochondrial and metabolic-based protective strategies in Huntington's disease: the case of creatine and coenzyme Q
Author(s): Naia, L; Ribeiro, MJ; Rego, AC
Source : REVIEWS IN THE NEUROSCIENCES Document Type : Article Volume : 23 Issue: 1 Pages: 13-28 DOI: 10.1515/RNS.2011.060 Published: 2012 FEB
Times Cited: 6
 
Title : Mitochondrial DNA 8993T > G Mutation in a Child With Ornithine Transcarbamylase Deficiency and Leigh Syndrome: An Unexpected Association
Author(s): Henriques, M; Diogo, L; Garcia, P; Pratas, J; Simoes, M; Grazina, M
Source : JOURNAL OF CHILD NEUROLOGY Document Type : Article Volume : 27 Issue: 8 Pages: 1059-1061 DOI: 10.1177/0883073811431015 Published: 2012 AUG
Times Cited: 4
 
Title : MITOCHONDRIAL IMPORTANCE IN ALZHEIMER'S, HUNTINGTON'S AND PARKINSON'S DISEASES
Author(s): Correia, SC; Santos, RX; Perry, G; Zhu, XW; Moreira, PI; Smith, MA
Source : NEURODEGENERATIVE DISEASES Document Type : Article; Book Chapter Volume : 724 Issue: Pages: 205-221 DOI: Published: 2012
Times Cited: 26
 
Title : Mitochondrial Metabolic Control of Microtubule Dynamics Impairs the Autophagic Pathway in Parkinson's Disease
Author(s): Cardoso, SM; Esteves, AR; Arduino, DM
Source : NEURODEGENERATIVE DISEASES Document Type : Article; Proceedings Paper Volume : 10 Issue: 1-4 Pages: 38-40 DOI: 10.1159/000332601 Published: 2012
Times Cited: 6
 
Title : Modeling epileptic brain states using EEG spectral analysis and topographic mapping
Author(s): Direito, B; Teixeira, C; Ribeiro, B; Castelo-Branco, M; Sales, F; Dourado, A
Source : JOURNAL OF NEUROSCIENCE METHODS Document Type : Article Volume : 210 Issue: 2 Pages: 220-229 DOI: 10.1016/j.jneumeth.2012.07.006 Published: 2012 SEP 30
Times Cited: 9
 
Title : NADPH Oxidase 1 Mediates alpha-Synucleinopathy in Parkinson's Disease
Author(s): Cristovao, AC; Guhathakurta, S; Bok, E; Je, G; Yoo, SD; Choi, DH; Kim, YS
Source : JOURNAL OF NEUROSCIENCE Document Type : Article Volume : 32 Issue: 42 Pages: 14465-14477 DOI: 10.1523/JNEUROSCI.2246-12.2012 Published: 2012 OCT 17
Times Cited: 28
 
Title : Neuropeptide Y inhibits interleukin-1 beta-induced microglia motility
Author(s): Ferreira, R; Santos, T; Cortes, L; Cochaud, S; Agasse, F; Silva, AP; Xapelli, S; Malva, JO
Source : JOURNAL OF NEUROCHEMISTRY Document Type : Article Volume : 120 Issue: 1 Pages: 93-105 DOI: 10.1111/j.1471-4159.2011.07541.x Published: 2012 JAN
Times Cited: 21
 
Title : Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures
Author(s): Baptista, S; Bento, AR; Goncalves, J; Bernardino, L; Summavielle, T; Lobo, A; Fontes-Ribeiro, C; Malva, JO; Agasse, F; Silva, AR
Source : NEUROPHARMACOLOGY Document Type : Article Volume : 62 Issue: 7 Pages: 2413-2423 DOI: 10.1016/j.neuropharm.2012.02.015 Published: 2012 JUN
Times Cited: 19
 
Title : Pharmacokinetics, Drug Interactions and Exposure-Response Relationship of Eslicarbazepine Acetate in Adult Patients with Partial-Onset Seizures Population Pharmacokinetic and PharmacokineticiPharmacodynamic Analyses
Author(s): Falcao, A; Fuseau, E; Nunes, T; Almeida, L; Soares-da-Silva, P
Source : CNS DRUGS Document Type : Article Volume : 26 Issue: 1 Pages: 79-91 DOI: Published: 2012
Times Cited: 13
 
Title : Preferential Effect of Premorbid Statins on Atherothrombotic Strokes through Collateral Circulation Enhancement
Author(s): Sargento-Freitas, J; Pagola, J; Rubiera, M; Flores, A; Silva, F; Rodriguez-Luna, D; Pineiro, S; Alvarez-Sabin, J; Molina, CA; Ribo, M
Source : EUROPEAN NEUROLOGY Document Type : Article Volume : 68 Issue: 3 Pages: 171-176 DOI: 10.1159/000337862 Published: 2012
Times Cited: 6
 
Title : Presynaptic alpha(2)-adrenoceptors control the inhibitory action of presynaptic CB1 cannabinoid receptors on prefrontocortical norepinephrine release in the rat
Author(s): Richter, H; Teixeira, FM; Ferreira, SG; Kittel, A; Kofalvi, A; Sperlagh, B
Source : NEUROPHARMACOLOGY Document Type : Article Volume : 63 Issue: 5 Pages: 784-797 DOI: 10.1016/j.neuropharm.2012.06.003 Published: 2012 OCT
Times Cited: 6
 
Title : Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences
Author(s): Ferreira, SG; Teixeira, FM; Garcao, P; Agostinho, P; Ledent, C; Cortes, L; Mackie, K; Kofalvi, A
Source : NEUROCHEMISTRY INTERNATIONAL Document Type : Article Volume : 61 Issue: 2 Pages: 219-226 DOI: 10.1016/j.neuint.2012.05.009 Published: 2012 JUL
Times Cited: 17
 
Title : Prevention of methamphetamine-induced microglial cell death by TNF-alpha and IL-6 through activation of the JAK-STAT pathway
Author(s): Coelho-Santos, V; Goncalves, J; Fontes-Ribeiro, C; Silva, AP
Source : JOURNAL OF NEUROINFLAMMATION Document Type : Article Volume : 9 Issue: Pages: - DOI: 10.1186/1742-2094-9-103 Published: 2012 MAY 29
Times Cited: 14
 
Title : Protective role of neuropeptide Y Y-2 receptors in cell death and microglial response following methamphetamine injury
Author(s): Goncalves, J; Ribeiro, CF; Malva, JO; Silva, AP
Source : EUROPEAN JOURNAL OF NEUROSCIENCE Document Type : Article Volume : 36 Issue: 9 Pages: 3173-3183 DOI: 10.1111/j.1460-9568.2012.08232.x Published: 2012 NOV
Times Cited: 20
 
Title : Regulation of catecholamine release in human adrenal chromaffin cells by beta-adrenoceptors
Author(s): Cortez, V; Santana, M; Marques, AP; Mota, A; Rosmaninho-Salgado, J; Cavadas, C
Source : NEUROCHEMISTRY INTERNATIONAL Document Type : Article Volume : 60 Issue: 4 Pages: 387-393 DOI: 10.1016/j.neuint.2011.12.018 Published: 2012 MAR
Times Cited: 12
 
Title : Stab wound injury of the zebrafish telencephalon: A model for comparative analysis of reactive gliosis
Author(s): Baumgart, EV; Barbosa, JS; Bally-Cuif, L; Gotz, M; Ninkovic, J
Source : GLIA Document Type : Article Volume : 60 Issue: 3 Pages: 343-357 DOI: 10.1002/glia.22269 Published: 2012 MAR
Times Cited: 43
 
Title : The EPILEPSIAE database: An extensive electroencephalography database of epilepsy patients
Author(s): Klatt, J; Feldwisch-Drentrup, H; Ihle, M; Navarro, V; Neufang, M; Teixeira, C; Adam, C; Valderrama, M; Alvarado-Rojas, C; Witon, A; Le Van Quyen, M; Sales, F; Dourado, A; Timmer, J; Schulze-Bonhage, A
Source : EPILEPSIA Document Type : Article Volume : 53 Issue: 9 Pages: 1669-1676 DOI: 10.1111/j.1528-1167.2012.03564.x Published: 2012 SEP
Times Cited: 31
 
Title : The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
Author(s): Guerreiro, RJ; Gustafson, DR; Hardy, J
Source : NEUROBIOLOGY OF AGING Document Type : Article Volume : 33 Issue: 3 Pages: 437-456 DOI: 10.1016/j.neurobiolaging.2010.03.025 Published: 2012 MAR
Times Cited: 68
 
Title : Ubiquitin proteasome system in Parkinson's disease: A keeper or a witness?
Author(s): Martins-Branco, D; Esteves, AR; Santos, D; Arduino, DM; Swerdlow, RH; Oliveira, CR; Januario, C; Cardoso, SM
Source : EXPERIMENTAL NEUROLOGY Document Type : Article Volume : 238 Issue: 2 Pages: 89-99 DOI: 10.1016/j.expneurol.2012.08.008 Published: 2012 DEC
Times Cited: 19