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IIIUC

Instituto de Investigação Interdisciplinar

Pharmacology & Toxicology

Title : A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondansetron HCl and diltiazem HCl
Author(s): Silva, SMC; Hu, LS; Sousa, JJS; Pais, AACC; Michniak-Kohn, BB
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 80 Issue: 3 Pages: 663-673 DOI: 10.1016/j.ejpb.2011.11.010 Published: 2012 APR
Times Cited: 11
 
Title : Antifouling foldable acrylic IOLs loaded with norfloxacin by aqueous soaking and by supercritical carbon dioxide technology
Author(s): Gonzalez-Chomon, C; Braga, MEM; de Sousa, HC; Concheiro, A; Alvarez-Lorenzo, C
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 82 Issue: 2 Pages: 383-391 DOI: 10.1016/j.ejpb.2012.07.007 Published: 2012 OCT
Times Cited: 12
 
Title : Comparison of deposited surface area of airborne ultrafine particles generated from two welding processes
Author(s): Gomes, JF; Albuquerque, PC; Miranda, RM; Santos, TG; Vieira, MT
Source : INHALATION TOXICOLOGY Document Type : Article Volume : 24 Issue: 11 Pages: 774-781 DOI: 10.3109/08958378.2012.717648 Published: 2012 SEP
Times Cited: 11
 
Title : Differentiation-Dependent Doxorubicin Toxicity on H9c2 Cardiomyoblasts
Author(s): Branco, AF; Sampaio, SF; Moreira, AC; Holy, J; Wallace, KB; Baldeiras, I; Oliveira, PJ; Sardao, VA
Source : CARDIOVASCULAR TOXICOLOGY Document Type : Article Volume : 12 Issue: 4 Pages: 326-340 DOI: 10.1007/s12012-012-9177-8 Published: 2012 DEC
Times Cited: 15
 
Title : Effects of an oral insulin nanoparticle administration on hepatic glucose metabolism assessed by C-13 and H-2 isotopomer analysis
Author(s): Reis, CP; Neufeld, R; Veiga, F; Figueiredo, IV; Jones, J; Soares, AF; Nunes, P; Damge, C; Carvalho, RA
Source : JOURNAL OF MICROENCAPSULATION Document Type : Article Volume : 29 Issue: 2 Pages: 167-176 DOI: 10.3109/02652048.2011.638992 Published: 2012
Times Cited: 0
 
Title : Essential Oil of Juniperus communis subsp alpina (Suter) Celak Needles: Chemical Composition, Antifungal Activity and Cytotoxicity
Author(s): Cabral, C; Francisco, V; Cavaleiro, C; Goncalves, MJ; Cruz, MT; Sales, F; Batista, MT; Salgueiro, L
Source : PHYTOTHERAPY RESEARCH Document Type : Article Volume : 26 Issue: 9 Pages: 1352-1357 DOI: 10.1002/ptr.3730 Published: 2012 SEP
Times Cited: 8
 
Title : Evaluation of hepatic glucose metabolism via gluconeogenesis and glycogenolysis after oral administration of insulin nanoparticles
Author(s): Woitiski, CB; Neufeld, RJ; Soares, AF; Figueiredo, IV; Veiga, FJ; Carvalho, RA
Source : DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY Document Type : Article Volume : 38 Issue: 12 Pages: 1441-1450 DOI: 10.3109/03639045.2011.653789 Published: 2012 DEC
Times Cited: 4
 
Title : Exposure to dibenzofuran triggers autophagy in lung cells
Author(s): Duarte, FV; Teodoro, JS; Rolo, AP; Palmeira, CM
Source : TOXICOLOGY LETTERS Document Type : Article Volume : 209 Issue: 1 Pages: 35-42 DOI: 10.1016/j.toxlet.2011.11.029 Published: 2012 FEB 25
Times Cited: 12
 
Title : Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo
Author(s): Duarte, S; Faneca, H; de Lima, MCP
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 423 Issue: 2 Pages: 365-377 DOI: 10.1016/j.ijpharm.2011.12.035 Published: 2012 FEB 28
Times Cited: 14
 
Title : Hepatocellular Carcinoma and Chemotherapy: The Role of p53
Author(s): Brito, AF; Abrantes, AM; Pinto-Costa, C; Gomes, AR; Mamede, AC; Casalta-Lopes, J; Goncalves, AC; Sarmento-Ribeiro, AB; Tralhao, JG; Botelho, MF
Source : CHEMOTHERAPY Document Type : Article Volume : 58 Issue: 5 Pages: 381-386 DOI: 10.1159/000343656 Published: 2012
Times Cited: 15
 
Title : Identification and Characterization of Stoichiometric and Nonstoichiometric Hydrate Forms of Paroxetine HCl: Reversible Changes in Crystal Dimensions as a Function of Water Absorption
Author(s): Pina, MF; Pinto, JF; Sousa, JJ; Fabian, L; Zhao, M; Craig, DQM
Source : MOLECULAR PHARMACEUTICS Document Type : Article Volume : 9 Issue: 12 Pages: 3515-3525 DOI: 10.1021/mp3003573 Published: 2012 DEC
Times Cited: 18
 
Title : In vitro salicylate does not further impair aging-induced brain mitochondrial dysfunction
Author(s): Marques-Aleixo, I; Rocha-Rodrigues, S; Santos-Alves, E; Coxito, PM; Passos, E; Oliveira, PJ; Magalhaes, J; Ascensao, A
Source : TOXICOLOGY Document Type : Article Volume : 302 Issue: 1 Pages: 51-59 DOI: 10.1016/j.tox.2012.07.018 Published: 2012 DEC 8
Times Cited: 4
 
Title : Inhibition of Bladder Tumor Growth by Chitooligosaccharides in an Experimental Carcinogenesis Model
Author(s): Fernandes, JC; Sereno, J; Garrido, P; Parada, B; Cunha, MFX; Reis, F; Pintado, ME; Santos-Silva, A
Source : MARINE DRUGS Document Type : Article Volume : 10 Issue: 12 Pages: 2661-2675 DOI: 10.3390/md10122661 Published: 2012 DEC
Times Cited: 10
 
Title : Malvidin-3-glucoside protects endothelial cells up-regulating endothelial NO synthase and inhibiting peroxynitrite-induced NF-kB activation
Author(s): Paixao, J; Dinis, TCP; Almeida, LM
Source : CHEMICO-BIOLOGICAL INTERACTIONS Document Type : Article Volume : 199 Issue: 3 Pages: 192-200 DOI: 10.1016/j.cbi.2012.08.013 Published: 2012 SEP 30
Times Cited: 19
 
Title : Methylglyoxal promotes oxidative stress and endothelial dysfunction
Author(s): Sena, CM; Matafome, P; Crisostomo, J; Rodrigues, L; Fernandes, R; Pereira, P; Seica, RM
Source : PHARMACOLOGICAL RESEARCH Document Type : Article Volume : 65 Issue: 5 Pages: 497-506 DOI: 10.1016/j.phrs.2012.03.004 Published: 2012 MAY
Times Cited: 72
 
Title : Minocycline exerts uncoupling and inhibiting effects on mitochondrial respiration through adenine nucleotide translocase inhibition
Author(s): Cuenca-Lopez, MD; Karachitos, A; Massarotto, L; Oliveira, PJ; Aguirre, N; Galindo, MF; Kmita, H; Jordan, J
Source : PHARMACOLOGICAL RESEARCH Document Type : Article Volume : 65 Issue: 1 Pages: 120-128 DOI: 10.1016/j.phrs.2011.08.007 Published: 2012 JAN
Times Cited: 10
 
Title : Mitochondrial Abnormalities and Oxidative Stress in Alzheimer's Disease Can Mitochondrial Reactive Oxygen Species Signaling Promote Neuronal Survival?
Author(s): Moreira, PI; Oliveira, CR
Source : MITOCHONDRIAL SIGNALING IN HEALTH AND DISEASE Document Type : Article; Book Chapter Volume : Issue: Pages: 391-414 DOI: Published: 2012
Times Cited: 0
 
Title : Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms
Author(s): Pereira, CV; Oliveira, PJ; Will, Y; Nadanaciva, S
Source : TOXICOLOGY AND APPLIED PHARMACOLOGY Document Type : Article Volume : 264 Issue: 2 Pages: 167-181 DOI: 10.1016/j.taap.2012.07.030 Published: 2012 OCT 15
Times Cited: 4
 
Title : Mucus thickness in the gastrointestinal tract of laboratory animals
Author(s): Varum, FJO; Veiga, F; Sousa, JS; Basit, AW
Source : JOURNAL OF PHARMACY AND PHARMACOLOGY Document Type : Article Volume : 64 Issue: 2 Pages: 218-227 DOI: 10.1111/j.2042-7158.2011.01399.x Published: 2012 FEB
Times Cited: 14
 
Title : Nerolidol effects on mitochondrial and cellular energetics
Author(s): Ferreira, FM; Palmeira, CM; Oliveira, MM; Santos, D; Simoes, AM; Rocha, SM; Coimbra, MA; Peixoto, F
Source : TOXICOLOGY IN VITRO Document Type : Article Volume : 26 Issue: 2 Pages: 189-196 DOI: 10.1016/j.tiv.2011.11.009 Published: 2012 MAR
Times Cited: 10
 
Title : Optimization of a parallel artificial membrane permeability assay for the fast and simultaneous prediction of human intestinal absorption and plasma protein binding of drug candidates: Application to dibenz[b,f]azepine-5-carboxamide derivatives
Author(s): Fortuna, A; Alves, G; Soares-da-silva, P; Falcao, A
Source : JOURNAL OF PHARMACEUTICAL SCIENCES Document Type : Article Volume : 101 Issue: 2 Pages: 530-540 DOI: 10.1002/jps.22796 Published: 2012 FEB
Times Cited: 10
 
Title : Semisynthetic Ursolic Acid Fluorolactone Derivatives Inhibit Growth with Induction of p21waf1 and Induce Apoptosis with Upregulation of NOXA and Downregulation of c-FLIP in Cancer Cells
Author(s): Leal, AS; Wang, R; Salvador, JAR; Jing, YK
Source : CHEMMEDCHEM Document Type : Article Volume : 7 Issue: 9 Pages: 1635-1646 DOI: 10.1002/cmdc.201200282 Published: 2012 SEP
Times Cited: 12
 
Title : Synthesis of Ninhydrin Derivatives and their Anticancer, Antimicrobial and Cholinesterase Enzymes Inhibitory Activities
Author(s): Ghalib, RM; Hashim, R; Mehdi, SH; Sulaiman, O; Silva, PSP; Jassbi, AR; Firuzi, O; Kawamura, F; Chan, KL; Murugaiyah, V
Source : LETTERS IN DRUG DESIGN & DISCOVERY Document Type : Article Volume : 9 Issue: 8 Pages: 767-774 DOI: Published: 2012 OCT
Times Cited: 3
 
Title : Syringeable Pluronic-alpha-cyclodextrin supramolecular gels for sustained delivery of vancomycin
Author(s): Simoes, SMN; Veiga, F; Torres-Labandeira, JJ; Ribeiro, ACF; Sandez-Macho, MI; Concheiro, A; Alvarez-Lorenzo, C
Source : EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Document Type : Article Volume : 80 Issue: 1 Pages: 103-112 DOI: 10.1016/j.ejpb.2011.09.017 Published: 2012 JAN
Times Cited: 35
 
Title : Tachyphylaxis to the Sumatriptan-Induced Contractile Effect in the Human Uterine Artery but Not in Human Cerebral Blood Vessels: Pharmacological Demonstration of the 5-HT1B Receptor Functionality Loss
Author(s): Silva, SA; Ribeiro, CAF
Source : PHARMACOLOGY Document Type : Article Volume : 89 Issue: 1-2 Pages: 29-36 DOI: 10.1159/000334930 Published: 2012
Times Cited: 2
 
Title : The anti-Candida activity of Thymbra capitata essential oil: Effect upon pre-formed biofilm
Author(s): Palmeira-de-Oliveira, A; Gaspar, C; Palmeira-de-Oliveira, R; Silva-Dias, A; Salgueiro, L; Cavaleiro, C; Pina-Vaz, C; Martinez-de-Oliveira, J; Queiroz, JA; Rodrigues, AG
Source : JOURNAL OF ETHNOPHARMACOLOGY Document Type : Article Volume : 140 Issue: 2 Pages: 379-383 DOI: 10.1016/j.jep.2012.01.029 Published: 2012 MAR 27
Times Cited: 18
 
Title : Thermoresponsive hydrogels with low toxicity from mixtures of ethyl(hydroxyethyl) cellulose and arginine-based surfactants
Author(s): Calejo, MT; Kjoniksen, AL; Pinazo, A; Perez, L; Cardoso, AMS; de Lima, MCP; Jurado, AS; Sande, SA; Nystrom, B
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 436 Issue: 1-2 Pages: 454-462 DOI: 10.1016/j.ijpharm.2012.07.018 Published: 2012 OCT 15
Times Cited: 13
 
Title : Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment
Author(s): Gomes-da-Silva, LC; Santos, AO; Bimbo, LM; Moura, V; Ramalho, JS; de Lima, MCP; Simoes, S; Moreira, JN
Source : INTERNATIONAL JOURNAL OF PHARMACEUTICS Document Type : Article Volume : 434 Issue: 1-2 Pages: 9-19 DOI: 10.1016/j.ijpharm.2012.05.018 Published: 2012 SEP 15
Times Cited: 20