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ANTÓNIO JOAQUIM MATOS MORENO |
Categoria profissional | Professor Associado com Agregação |
Morada institucional | Departamento de Ciências da Vida Faculdade de Ciências e Tecnologia Universidade de Coimbra Calçada Martim de Freitas 3000-456 Coimbra |
Gabinete | Piso 0 do Colégio de Jesus |
Telefone | (+351) 239 240 761 |
Extensão interna | 262 261 |
Fax: | (+351) 239 240 701 |
Email | moreno@ci.uc.pt |
Áreas de interesse | Bioenergética |
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Categoria profissionalProfessor Associado com AgregaçãoMorada institucionalDepartamento de Ciências da Vida Faculdade de Ciências e Tecnologia Universidade de Coimbra Calçada Martim de Freitas 3000-456 CoimbraGabinetePiso 0 do Colégio de Jesus Telefone(+351) 239 240 761Extensão interna262 261Fax:(+351) 239 240 701Emailmoreno@ci.uc.ptÁreas de interesseBioenergética
Publicações mais relevantes/recentes:
Moreno
A.J., Serafim T.L.M., Oliveira P.J., and Madeira V.M.C., Toxicity of
carbaryl on hepatic mitochondrial bioenergetics – selective inhibition
of the mitochondrial respiratory chain, Chemosphere, 66: 404-411 (2007).
Moreno
A.J.M., Oliveira P.J., Nova C.D., Alvaro A.R., Moreira R.A., Santos
S.M.D, Macedo T., Unaltered Hepatic Oxidative Phosphorylation and
Mitochondrial Permeability Transition in Nimesulide-treated Rats -
Relevance for Early Cell Markers of Nimesulide Toxicity, J. Biochem.
Mol. Toxicol. 21(2): 53-61 (2007).
Moreira P.I., Custódio
J.B.A., Nunes E., Moreno A.J.M., Seiça R., Oliveira C.R., Santos M.S.,
Estradiol affects liver mitochondrial function in ovariectomized and
tamoxifen-treated ovariectomized female rats, Toxicol. Appl. Pharmacol.
221(1):102-110 (2007).
Pereira G.C., Branco A.F., Matos J.A.C.,
Pereira S.L., Parke D., Perkins E.L., Serafim T.L., Sardão V.A., Santos
M.S., Moreno A.J.M., Holy J., and Oliveira P.J.,
Mitochondrially-targetted Effects of Berberine on K1735-M2 Mouse
Melanoma Cells - Comparison with Direct Effects on Isolated
Mitochondrial Fractions, J. Pharmacol. Exp. Therap. 323(2): 636-649
(2007).
Fernandes M.A.S., Marques R.J.F., Vicente J.A.F., Santos
M.S., Monteiro P., Moreno A.J.M., and Custódio J.B.A., Sildenafil
citrate concemtrations not affecting oxidative ohosphorylation depress
H2O2 generation by rat heart mitochondria, Mol. Cell Biochem., 309:
77-85 (2008).
Fernandes M.A.S., Pereira S.P.S., Jurado A.S.,
Custódio J.B.A., Santos M.S., Moreno A.J.M., Duburs G., and Vicente
J.A.F., Comparative effects of three 1,4-dihydropyridine derivatives
[OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver
mitochondrial bioenergetics and on the physical properties of membrane
lipid bilayers: relevance to the length of thealkoxyl chain in positions
3 and 5 of the DHP ring, Chem. Biol. Interact., 173 (3): 195-204
(2008).
Pupure, J., Fernandes, M.A.S., Santos M.S., Moreno,
A.J.M., Kalvinsh, I., Klusa, V., Oliveira, C.R., Mitochondria as a
target for mildronate’s protective effects in azidothymidine
(AZT)-induced toxicity of isolated rat liver mitochondria, Cell Biochem.
Function, 26 (5): 620-531 (2008).
Monteiro, J.P., Oliveira,
P.J., Moreno A.J.M., Jurado A.S., Disruption of hepatic mitochondrial is
not a primary mechanism for the toxicity of methoprene — relevance for
toxicological assessment, Chemosphere, 72 (9): 1347-1354 (2008).
Serafim
T.L., Matos J.A., Sardão V.A., Pereira G.C., Branco A.F., Pereira S.L.,
Parke D., Perkins E.L., Moreno A.J., Holy J., Oliveira P.J.,
Sanguinarine Cytotoxicity on Mouse Melanoma K1735-M2 Cells - Nuclear
versus Mitochondrial Effects, Biochemical Pharmacol., 76 (11): 1459-1475
(2008).
Diana Pinto-Basto, Silva J.P., Queiroz M.J.R.P., Moreno A.J.M., and Coutinho O.P., Antioxidant activity of synthetic diarylamines: a mitochondrial and cellular approach, Mitochondrion, 9(1): 17-26 (2009).
Pereira, S.P., Fernandes, M.A., Martins, J.D.,
Santos, M.S., Moreno, A.J.M., Vicente, J.A., Videira, R.A., and Jurado,
A.S., Toxicity assessment of the herbicide metolachlor. comparative
effects on bacterial and mitochondrial model systems, Toxicology in
Vitro, 23: 1585-1590 (2009).
Pereira, S.P., Pereira, G.C.,
Moreno, A.J.M. Oliveira, P.J. Can We Predict Drug Safety and Decrease
Animal Experiments Testing by Using Isolated Mitochondria? ATLA, 37:
355-365 (2009).
Fernandes, M.A.S, Santos M.S., Moreno, A.J.M.,
Chernova, L., Krauze, A., Duburs, G., Vicente, J.A.F. Effects of
5-acetyl(carbamoyl)-6-methylsulfanyl-1,4-dihydropyridine-5-carbonitriles
on rat liver mitochondrial function. Toxicol. in Vitro, 23: 1333-1341
(2009).
Rodrigues, A.S., Lacerda, B., Moreno, A.J.M., and
Ramalho-Santos, J., Proton leak modulation in testicular mitochondria
affects reactive oxygen species production and lipid peroxidation. Cell
Biochem. Funct., 28 (3): 224-231 (2010).
Custódio J.B.A., Santos M.S., Gonçalves D.I.R., Moremo A.J.M., Fernandes E, Bastos M.L., Carvalho F., Vicente J.A.F., and Fernandes M.A.S. Comparative effects of 3,4-methylenedioxymethamphetamine and 4-methylthioamphetamine on rat liver mitochondrial function. Toxicology, 270: 99-105 (2010).
Moreira
P.I., Custódio J.B.A., Nunes E., Oliveira P.J., Moreno A., Seiça R.,
Oliveira C.R., and Santos M.S., Mitochondria from distinct tissues are
differently affected by 17b-estradiol and tamoxifen. J. Steroid Biochem.
Mol. Biol., 123:8-16 (2011).
Mota P.C., Cordeiro M., Pereira
S.P., Oliveira P.J., Moreno A.J., and Ramalho-Santos J., Differential
effects of p,p´-DDE on testis and liver mitochondria: Implications for
reproductive toxicology. Reprod. Toxicol., 31: 80-85 (2011).
Capítulos de Livros
Oliveira
P.J., and Moreno A.J.M, Carvedilol, and hypertensive drug, protects
heart mitochondria from oxidative damage (In Mitochondrial Pharmacology
and Toxicology, Moreno A.J.M., editor, Transworld Research Network,
India), 2006.
Moreno A.J.M., and Vicente J.A., Use of a
calcium-sensitive electrode for studies on mitochondrial calcium
transport. (In MITOCHONDRIAL BIOENERGETICS: Methods and Protocols,
Carlos M. Palmeira and António J. Moreno (eds), Methods in Molecular
Biology, Volume 810, 207-217, Springer Protocols, Humana Press, 2012.