As real-life applications loom, graphene and graphene-based materials are approaching the industrial production stage . Upscaled graphene and 2D materials growth processes can be bottom-up and top-down, such as chemical vapor deposition (CVD) and liquid phase exfoliation (LFE). While CVD is particularly suitable for high-mobility single-layer graphene for micro and nanoelectronic devices, LFE methods allow for directly depositing multi-layered films at low cost over large-area substrates, like those used in macroelectronics . In this presentation, we report biosensing chips based on CVD graphene field-effect transistor (GFET) microelectronic arrays capable of detecting dopamine in attomolar concentrations in mice brain samples  or discriminating between different Port wine grapevine varieties based on the number of SNPs that are present in the studied portion of their genome, again with an attomolar limit of detection .
In a different approach, graphene is used as a sensing platform for super-resolution microscopy and bio-sensing by resonance energy transfer between DNA origami labeled with a fluorophore, immobilized on the graphene surface. A Fluorescence Imaging (FLIM) optical microscopy setup is used for imaging .
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Organized by: Paulo Brás, Paulo Silva, Jaime Silva