NetworktDCS

Transcranial direct current stimulation (tDCS) is routinely used in basic and translational research, but its efficacy has been challenged. The issues against tDCS may derive from insufficient understanding of how tDCS works at the systems level. Because of the widespread use of tDCS, as well as the fact that the technique has the potential to be a central tool in the neurosciences, it is of the utmost importance to increase our understanding of the mechanisms of tDCS at the systems level. In our project will use functional magnetic resonance imaging to unravel three systems level properties of tDCS that may be central for understanding the full potential of this technique: 1) Are there distal effects of tDCS? 2) Are these effects functionally flexible? 3) Are these effects additive? This project will have a broad and durable impact on our understanding of tDCS, and will boost the spectrum of possible applications of technique in basic and translational research.