Integrated Member
Biografia
Background
- PharmD Pharmaceutical Sciences
- PhD in Pharmaceutical Sciences (Pharmacology)
Scientific interests | skills
- Development, validation and employment of in vitro techniques to:
• estimate drugs permeability through intestinal mucosa and blood-brain barrier,
• estimate drugs plasma protein binding,
• identify substrates of efflux transporters (e.g. P-glycoprotein, breast cancer receptor protein);
• characterize the metabolism of new chemical entities.
- Investigation of intranasal administration potential to delivery drugs into the brain or bloodstream in comparison to the most common routes (oral, IV, IP).
- Development and full validation of bioanalytical methodologies to quantify drugs and metabolites in biological samples by HPLC.
- Pharmacokinetic monitoring of antiepileptic drugs and personalized pharmacotherapy.