Programme

AHA Mini-Symposium: Stem cells in ageing and metabolism

9:00 Opening Session

Thomas von Zglinicki - Professor of Cell Gerontology, Newcastle University

Cláudia Cavadas - Vice-Rector of University of Coimbra

Session 1

Chairperson: Satomi Miwa - Newcastle University

9:30-10:10 Moustapha Kassem (University of Southern Denmark) ‘Accelerated Aging of skeletal stem cells in metabolic bone diseases: contribution to bone fragility’

10:10-10:50 Lino Ferreira (University of Coimbra) ‘Cardiovascular ageing and stem cells’

10:50-11:20 Coffee break

11:20-12:00 Eugene Berezikov (Eriba, University of Groningen) ‘Stem cells, regeneration and aging in the flatworm Macrostomum lignano’

12:00-12:40 Laura Greaves (Newcastle University) ‘MtDNA mutation and stem cell function’

12:40-14:30 Lunch Break

Session 2

Chairperson: Marco Demaria - University of Groningen

14:30-15:10 Paul Robbins (University of Minnesota) ‘Stem cell extracellular vesicles as senotherapeutics’

15:10-15:50 A. Cristina Rego (University of Coimbra) ‘Mitochondrial deregulation in stem cell models of Huntington's disease’

15:50-16:20 Coffee break

16:20-17:00 Luis Almeida (University of Coimbra) ‘Gene and stem cell therapies’

17:00-17:40 João Ramalho Santos (University of Coimbra) ‘Pluripotency, Metabolism and aging’

17:40-19:00 Poster session

Session 1

9:00-9:30 - Registration

9:30-11:30 Tour at University of Coimbra

12:30-14:00 Lunch at the Hotel

Session 2

Chairperson: Cláudia Cavadas - University of Coimbra

14:00-14:45 Tips for Succefull Science communication with peers. Nuno Raimundo - MIA Portugal Principal Investigator

15:00-17:25 Science communication for general public and Media Training.

17:30-21:00 City tour + dinner at the hotel.

21:00-22:30 Poster session | meet & greet

Session 1

Basic mechanisms of aging

Chairperson: Thomas von Zglinicki - Newcastle University

9:00-9:45 Lene Rasmussen (University of Copenhagen), Genomic instability

9:45-10:30 Marco Demaria (University of Groningen), Cell senescence

10:30-11:00 Break

11:00-11:45 Satomi Miwa (Newcastle University), 'Mitochondria and metabolism'

11:45-12:30 Short talks selected from submitted abstracts

• T Blake Monroe;
• Sebastian Mackedenski;
• Chen Ge.

12:30-14:00 Lunch

Session 2

The aging brain

Chairperson: Ira Milosevic - MIA Portugal | UC

14:00-14:45 Claudia Almeida (NOVA Medical School - NMS), 'Neuronal trafficking defects during normal ageing'

14:45-15:30 Bart Eggen (University of Groningen)

15:30-16:00 Break

16:00-16:45 Ira Milosevic (MIA-Portugal - Multidisciplinary Institute of Ageing), 'Improving synaptic transmission in the ageing brain'

16:45-17:30 Short talks selected from submitted abstracts:

• Isaura Vanessa Antunes Martins

• Sara Matias Carmo Silva

• João Pedro Ferreira da Costa Novo

17:30-19:00 Poster session

Session 1

Aging interventions

Chairperson: Marco Demaria - University of Groningen

9:00-9:45 Laura Niedernhofer (University of Minnesota) 'The Hallmarks of Aging as a guide for Geroscience-targeted therapies'

9:45-10:30 Thomas von Zglinicki (Newcastle University) 'Chronic inflammation and cell senescence – an intimate relationship'

10:30-11:00 Coffee-break

11:00-11:45 Cláudia Cavadas (University of Coimbra) 'Neuroendocrinology and ageing: from mechanisms to translational approaches'

11:45-12:30 Short talks selected from submitted abstracts

• Marisa Ferreira-Marques

• Allancer Divino de Carvalho Nunes

• Anna Francis Carey

12:30-14:00 Lunch

Session 2

Treating aging in humans

Chairperson: Nuno Raimundo - MIA-Portugal | UC

14:00-14:45 Eline Slagboom (Leiden University), 'Lifestyle interventions in elderly and how to monitor the response | human ageing and interventions'

14:45-15:15 James Kirkland (Mayo Clinic) - Online, 'Senolytics: the Path to Translation for Multiple Diseases and Age-Related Dysfunction'

15:15-15:45 Tamar Tchkonia (Mayo Clinic) - Online, 'Biomarkers for Geroscience- guided Clinical Trials'

Break

16:00-16:45 Ioakim Spyridopoulos (Translational and Clinical Research Institute, Newcastle University), 'Targeting immune ageing in cardiovascular disease'

16:45-17:30 Short talks selected from submitted abstracts:

• José Pedro Quinta Araújo Castro;
• Rebekah-Louise Anne Scanlan;
• Karla Valdivieso.

17:30-19:00 Panel discussion

Session 1

Translation and Impact

Chairperson: Satomi Miwa - Newcastle University

9:00-9:45 Lino Ferreira, 'Colab4Ageing'

9:45-10:30 David Weinkove (Magnitude Biosciences Ltd. U.K.), 'Establishing a spinout company in the field of ageing'

10:30-11:00 Break

11:00-11:45 Andy Filby - online (Newcastle University), 'Being a technology scientist and running a core facility for research; how to most effectively work with core facilities; making an impact'

11:45-12:30 Overall conclusions, feedback, group photos

12:30-13:00 Closing Session

Manuel Santos - MIA Portugal Scientific Director
Cláudia Cavadas - Vice-Rector of the University of Coimbra

Lunch

Departure