Catalog

Investigations on chemical reactivity at low-temperatures (down to 4 K) trigger by narrowband UV-Vis-IR radiation and using steady-state FTIR spectroscopy

i) fluorescência em estado estacionário ii) fluorescência resolvida no tempo

Singlet oxygen detection and quantification.

i) viabilidade celular; ii) fototoxicidade; iii) "uptake"; e iv) mecanismo de morte celular

Infrared and Raman spectroscopic analysis applied to materials and food science, astrochemistry, arts and cultural heritage, and fundamental science

High precision thermochemistry studies of transient species. Quantum yields of fast photoinduced processes. Detection of fast structural volume changes in molecules and macromolecules.

Based on acoustic detection of optical absorption from endogenous chromophores (e.g. hemoglobin) or exogenous contrast agents (organic dyes or nanoparticles), it is an imaging modality with great potential for preclinical research and clinical practice.

Ultrafast transient absorption spectroscopy

Molecular tumour profiling can predict an individual’s prognosis by interpreting the expression pattern of a panel of tumour-related genes.

This procedure allows to study DNA and RNA from cancer cells from a tumor that are circulating in the blood. May be used to help find cancer at an early stage and be used to help plan treatment.

Investigate the microbiota composition of complex environments. This application is based on the amplification of a specific region of the 16S rRNA gene for bacteria or the ITS (Internal Transcribed Spacer) region for fungi.

This application is commonly used to identify exon-level copy number variants (CNVs) not detected by conventional sequencing.

NGS panels are collections of genes that have been selected to identify a genetic cause of disease or to study regions of interest. It allows simultaneous sequencing of all the genes, in a faster and more cost-efffective way than conventional sequencing.

RNA-seq allows gene expression analysis across the whole transcriptome or specifically, reveal the presence and quantity of RNA of selected genes.

SNVs/SNPs identification. This application is also used to identify exon-level copy number variants (CNVs).

SNVs/SNPs identification.

Electrofisiologia

Aplicação Clinica: POC, Dor, Depressão

Aplicação Clinica: Tumores Neuroendocrinos

Aplicação Clinica: D. Parkinson

Aplicação Clinica: Epilepsia

Aplicação Clinica: Tumores Cerebrais

Aplicação Clinica: Infecção/Inflamação cerebral

Aplicação Clinica: Síndromes Parkinsónicos

Aplicação Clinica: Cardiologia

Diagnóstico em Carcinoma da Próstata

Aplicação Clinica: Oncologia

Aplicação Clinica: D. Parkinson

Estudo de corpo inteiro ou cardíaco

Aplicação Clinica: Metastização óssea

Aplicação Clinica: Carcinoma da Próstata

Aplicação Clinica: D. Alzheimer

Aplicação Clinica: D. Alzheimer

Exames de Diagnóstico e Investigação

Access to cluster Navigator for computing, storage, visualization and data backup. Support is available to all users through a ticketing system.

Scanning of slides for digital support

Multiphoton microscopy on live or fixed samples, from different origins. Specialized technical training.

Confocal microscopy on live or fixed biological samples, from different origins. Specialized technical training.

Widefield Microscope with LED-based system (UV 385/30 nm, B 469/38 nm, G 555/30 nm, Y 590/27 nm, and R 631/33 nm) Scanning Confocal Microscope with 4 laser units (Diode 405 nm; Argon/2: 458, 488, 514 nm; DPSS: 561 nm and HeNe: 633 nm)