University of Coimbra - Protein Biophysical Chemistry Group

Patents

2-THIOXOTHIAZOLIDIN-4-ONE DERIVATIVES ACTIVE AS TRANSTHYRETIN LIGANDS AND USES THEREOF,
- International Application No.: PCT/PT2015/050010
- Publication Date: 26.05.2016
- International Filing Date: 20.11.2015
- Priority Data: 21.11.2014 US
- Inventors: PONTES MEIRELES FERREIRA DE BRITO, Rui Manuel; VIEIRA SIMÕES, Carlos Jose; DE VASCONCELOS DIAS DE PINHO MELO, Teresa Margarida; DA SILVA VICTOR, Bruno Lourenço; LOURENÇO DE ALMEIDA, Zaida Catarina; CABRAL LOPES, Ana Lucia; OLIVEIRA NASCIMENTO, Bruno Filipe.

BIS-FURAN DERIVATIVES AS TRANSTHYRETIN (TTR) STABILIZERS AND AMYLOID INHIBITORS FOR THE TREATMENT OF FAMILIAL AMYLOID POLYNEUROPATHY (FAP)
- International Application No.: PCT/IB2016/053546
- Publication Date: 22.12.2016
- International Filing Date: 15.06.2016
- Priority Data: 05.06.2015 US
- Inventors: VIEIRA SIMÕES, Carlos José; LOURENÇO DE ALMEIDA, Zaida Catarina; VASCONCELOS DIAS DE PINHO E MELO, Teresa Margarida; PONTES MEIRELES FERREIRA DE BRITO, Rui Manuel; SILVA COSTA, Dora Cristina; CABRAL CARDOSO LOPES, Ana Lúcia; (PT).